Pharmacology NURS 251 Module Exam 7 portage learning/ABCnursing/Geneva college Questions and Answer

Question 1 What type of gastric acid is released by the parietal cells? Answer: Hydrochloric Acid (HCl) Question 2 Select the substance below that is a major stimulator for the release of gastric juices. Acetylcholine HCl Substance P Serotonin Question 3 Describe the role of gastrin in the release of gastric acid. Answer: Gastrin binds to its target receptors stimulating the release of more histamine and HCl. The histamine then binds to the H2 receptors on the parietal cells which increases the amount of HCl or gastric acid released. Question 4 Name the type of bacteria that is the primary cause of peptic ulcers. Answer: Helicobacter Pylori or just H. Pylori Question 5 A patient has been diagnosed with a peptic ulcer not caused by bacteria. Select the drug below least likely to have played a part in causing this ulcer. Ibuprofen Aspirin Amoxicillin Naproxen Question 6 True or False. The pain associated with duodenal ulcers is often relieved with food. True False Question 7 What does GERD stand for? Answer: Gastroesophageal reflux disease Question 8 Select the TRUE statement regarding GERD. Synonymous with occasional heartburn LES loosens Symptoms cannot be impacted by diet changes H2 blockers are the most effective treatment Question 9 In reference to the treatment of Peptic ulcers caused by H. Pylori, what three classes of medications are most often used in the treatment regimens? Answer: Antibiotics, bismuth salts, and PPIs Question 10 Select the antibiotic that is not recommended for the treatment of H. Pylori. Amoxicillin Levofloxacin Clarithromycin Tetracycline Question 11 True or False: “Quadruple therapy” refers to a treatment regimen for peptic ulcers including antibiotics, bismuth, and H2 antagonists. True False False. It is a treatment regimen for peptic ulcers including antibiotics, bismuth, and PPIs Question 12 Misoprostol is specifically used for ulcers caused by Answer: NSAIDs Question 13 Name the two primary classes of antisecretory drugs used in the management of GERD. Answer: H2 receptor antagonists and Proton pump inhibitors. Question 14 Select a lifestyle modification that would likely improve the symptoms of a patient suffering from frequent heartburn. Smoking cessation Increased caffeine intake Increased Stress Weight gain Question 15 True or False. Misoprostol is contraindicated for use during pregnancy. True False Question 16 True or False. The development of PPIs has essentially made the use H2 antagonists for the treatment of GERD obsolete. True False False. In mild-moderate GERD, the H2 antagonists are a great option. They have a longer duration of action than something like an OTC antacid and provide good relief. However, in severe GERD or in cases where there is ulcerative damage then PPIs are considered first line therapy. Question 17 Which H2 receptor antagonist has been associated with the most drug interactions, limiting its use? Answer: cimetidine