https://www.stuvia.com/
TEST BANK FOR MODERN BLOOD BANKING &
h h h h h h
TRANSFUSION PRACTICES 7TH EDITION BY D
h h h h h h
ENISE M HARMENING
h h
9780803668881 CHAPTER 1-
h h
29 COMPLETE GUIDE
h h
,https://www.stuvia.com/
Chapter 1 RBCs and Platelet Preservation: Historical Perspectives and Current Trends
h h h h h h h h h h
MultiplehChoice
Identifyhthehchoicehthathbesthcompleteshthehstatementhorhanswershthehquestion.
1. Whichhmetabolichpathwayhishresponsiblehforhgeneratingh90%hofhthehATPhforhthehRBC?
a. Pentosehphosphatehshunt c. Glycolysis
b. Luebering-Rapoporthshunt d.h Methemoglobinhreductase
2. Ahunithofhbloodhwashreturnedhtohthehbloodhbankhbeforehithwashspiked.hApparentlyhthehpatient’shIVhfailed.hTheh
unithofhbloodhwashoutsidehthehbloodhbankhforh35hminutes.hWhichhofhthehstatementshbelowhishmosthaccurate?
a. Thehunithofhbloodhshouldhbehdiscardedhimmediately.
b. Thehunithofhbloodhcanhbehreturnedhtohinventory.
c. Thehunithofhbloodhmusthbehtransfusedhwithinh4hhourshorhbehdiscardedhaththehendhofhthathtime.
d. Thehunithofhbloodhmusthbehtransfusedhwithh24hhours.
3. Whathishthehaveragehdiameterhofhahplatelet?
a. 5htoh10hµm c. 1htoh2hµm
b. 2htoh4hµm d.h h 4htoh6hµm
4. Inhthehnormalhhemoglobin-
oxygenhdissociationhcurve,hwhathpercentagehofhoxygenhishreleasedhtohthehtissueshwhenhPO2h averagesh40hm
mhHg?
a. 75% c. 100%
b. 25% d.h 50%
5. Whathfactorsharehknownhtohinfluencehplatelethmetabolismhandhfunction?
a. Storagehtemperature c. Platelethcount
b. InitialhpH d.h Allhofhthehabove
6. Whichhofhthehfollowinghredhbloodhcellhmorphologieshmayhbehpresenthonhthehperipheralhbloodhsmearhashahresulth
ofhlosshofhRBChmembrane?
a. Spherocytes c. Burrhcells
b. Targethcells d.h Schistocytes
7. Whathdoeshthehtermhautologoushtransfusionhreferhto?
a. Ahparenthdonatinghbloodhforhhishorhherhchild
b. Anhindividualhdonatinghbloodhforhahfriend
c. Anhindividualhdonatinghbloodhforhahrelative
d. Anhindividualhdonatinghbloodhforhhishorhherhownhtransfusion
8. Whathishthehprimaryhfunctionhofhhemoglobin?
a. Ironhmetabolism c. Oxygenhtransport
b. Porphyrinhsynthesis d.h Signalhtransduction
9. Allhofhthehfollowinghareashofhredhbloodhcellhbiologyharehcrucialhforhnormalherythrocytehsurvivalh except:
a. Cellularhmetabolism. c. SitehofhthehABOhantigenhattachment.
b. RBChmembrane. d.h Hemoglobinhstructure.
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h 10.h WhathishthehcorrecthbiochemicalhcompositionhofhthehRBChmembrane?
a. 52%hprotein,h40%hlipid,h8%hcarbohydrate
b. 40%hprotein,h8%hlipid,h52%hcarbohydrate
c. 8%hprotein,h52%hlipid,h40%hcarbohydrate
d. 8%hlipid,h40%hcarbohydrate,h52%hprotein
h 11.h Allhofhthehfollowinghbiochemicalhchangesharehassociatedhwithhlosshofhredhbloodhcellhviabilityhuponhstorage
except:
a. DecreasedhpH. c. IncreasedhATPhlevel.
b. Losshofhredhbloodhcellhfunction. d.h Decreasedhglucosehconsumption.
h 12.h Whichhredhbloodhcellhpreservativehhashahstoragehtimehofh35hdays?
a. ACD c. AS-1
b. CPDA-1 d.h h CPD
h 13.h ThehRBChmembranehishrelativelyhpermeablehtohallhofhthehfollowinghexcept:
a. Chloride. c. Bicarbonate.
b. Sodium. d.h Water.
h 14.hWhathpercentagehofhplateletshishsequesteredhinhthehspleenhashfunctionalhreservehafterhbeinghreleasedhfromhtheh
bonehmarrow?
a. 30% c. 10%
b. 50% d.h h 25%
h 15.h Whathishthehmajorhbiochemicalhconsiderationhinhplatelethstorage?
a. Glucosehmetabolism c. Productionhofhcarbonhdioxide
b. Oxygenhsupply d.h RegulationhofhpH
h 16.hWhathwouldhthehhemoglobin-
oxygenhdissociationhcurvehdepicthinhahpatienthexhibitinghclinicalhsignshofhalkalosis?
a. Normal c. Shifthtohthehright
b. Shifthtohthehleft d.h Nonehofhthehabove
h 17.h Namehthehmainhlipidhcomponentshofhahredhbloodhcellhmembrane.
a. Phospholipid c. Glycolipid
b. Sphingomyelin d.h GlycophorinhA
h 18.h ThehABOhbloodhgroupshwerehdiscoveredhinh1901hbyhwhom?
a. CharleshDrew c. LoutithandhMollison
b. KarlhLandsteiner d.h EdwardhLindeman
h 19.hAhstandinghorderhofhplateletshwashshippedhtohyourhfacilityhbyhyourhsupplier.hIthwashinadvertentlyhlefthinhthehcor
nerhofhthehdepartmenthuntilhdiscoveredh36hhourshlater.hWhathwouldhthehappropriatehactionhbehforhthehbloodhban
ker?
a. Ifhthehtemperaturehinhthehboxhwash22h+/-
h2°ChandhthehplatelethswirlhseemedhOK,hithwouldhbehOKhtohaccepththehunithintohinventory.
b. Thehplateletshhavehfallenhoutsidehthehsupplier’shqualityhassurance.hThehunithshouldhbehdis
cardedhbecausehthehpHhhashprobablyhdroppedhtoohlowhandhplatelethactivationhhashbeenhco
mpromised.
c. Ifhthehtemperaturehwash1°Chtoh6°ChandhthehplatelethswirlhseemedhOK,hithwouldhbehOKhto
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accepththehunithintohinventory.
d. IfhthehplateletshappearedhOKhandhpassedhthehplatelethswirlhtesthafterhbeinghplacedhonhtheh
agitator,htheyhcouldhbehacceptedhintohthehinventory.
h 20.h Whichhmetabolichpathwayhpermitshthehaccumulationhofh2,3hdiphosphoglycerateh(2,3-DPG)?
a. Glycolysis c. Pentosehphosphatehshunt
b. Luebering-Rapoporthshunt d.h Methemoglobinhreductase
h 21.h Allhofhthehfollowingharehconsistenthwithhah"shifthtohthehright"hofhthehhemoglobin-oxygenhdissociationhcurve
except:
a. Increasedh2,3-DPG.
b. 50%hO2h saturationhtohtissues.
c. Decreasedh2,3-DPG.
d. DecreasedhhemoglobinhaffinityhforhO2.
h 22.h Whathishthehnormalhplatelethcounthrangehperhcubichmillimeter?
a. 100htoh350 c. 50,000htoh200,000
b. 150,000htoh350,000 d.h 350,000htoh500,000
h 23.h Whathcryoprotectivehagenthishaddedhtohredhbloodhcellshuponhfreezing?
a. Dextrose c. Glycerol
b. Adsol d.h Allhofhthehabove
h 24.h Ifhplateletsharehtohbehstoredhforh5hdayshonhahrotator,hwhathishthehoptimalhstoragehtemperature?
a. 1°Chtoh6°C c. 35°Chtoh37°C
b. 20°Chtoh24°C d.h 1°Chtoh10°C
h 25.h Whathrolehdohplateletshplayhinhhemostasis?
a. Maintenancehofhvascularhintegrity
b. Initialharresthofhbleedinghbyhplatelethplughformation
c. Stabilizationhofhthehhemostatichplug
d. Allhofhthehabove
h 26.h Whichhofhthehfollowinghbesthdescribesh"integral"hmembranehproteins?
a. Residehaththehcytoplasmichsurfacehofhmembrane
b. Spanhthehentirehmembranehsurface
c. Formhthehredhbloodhcellhcytoskeleton
d. Nonehofhthehabove
h 27.h Howhishstroma-freehhemoglobinhsolutionhprepared?
a. Outdatedhredhbloodhcellsharehconcentrated,handhstromahishremoved.
b. Outdatedhredhbloodhcellsharehdilutedhwithhsaline,handhstromahishremoved.
c. Outdatedhredhbloodhcellsharehlysed,handhstromahishremoved.
d. Nonehofhthehabove
h 28.h WhathishthehnormalhlifehspanhofhanhRBC?
a. 100hdays c. 120hhours
b. 120hdays d.h 2hdays
h 29.h RegardinghlosshofhRBChmembranehdeformability,hallhofhthehfollowingharehtruehexcept:
a. IncreasehinhATPhlevel.
b. DecreasehinhATPhlevel.
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TEST BANK FOR MODERN BLOOD BANKING &
h h h h h h
TRANSFUSION PRACTICES 7TH EDITION BY D
h h h h h h
ENISE M HARMENING
h h
9780803668881 CHAPTER 1-
h h
29 COMPLETE GUIDE
h h
,https://www.stuvia.com/
Chapter 1 RBCs and Platelet Preservation: Historical Perspectives and Current Trends
h h h h h h h h h h
MultiplehChoice
Identifyhthehchoicehthathbesthcompleteshthehstatementhorhanswershthehquestion.
1. Whichhmetabolichpathwayhishresponsiblehforhgeneratingh90%hofhthehATPhforhthehRBC?
a. Pentosehphosphatehshunt c. Glycolysis
b. Luebering-Rapoporthshunt d.h Methemoglobinhreductase
2. Ahunithofhbloodhwashreturnedhtohthehbloodhbankhbeforehithwashspiked.hApparentlyhthehpatient’shIVhfailed.hTheh
unithofhbloodhwashoutsidehthehbloodhbankhforh35hminutes.hWhichhofhthehstatementshbelowhishmosthaccurate?
a. Thehunithofhbloodhshouldhbehdiscardedhimmediately.
b. Thehunithofhbloodhcanhbehreturnedhtohinventory.
c. Thehunithofhbloodhmusthbehtransfusedhwithinh4hhourshorhbehdiscardedhaththehendhofhthathtime.
d. Thehunithofhbloodhmusthbehtransfusedhwithh24hhours.
3. Whathishthehaveragehdiameterhofhahplatelet?
a. 5htoh10hµm c. 1htoh2hµm
b. 2htoh4hµm d.h h 4htoh6hµm
4. Inhthehnormalhhemoglobin-
oxygenhdissociationhcurve,hwhathpercentagehofhoxygenhishreleasedhtohthehtissueshwhenhPO2h averagesh40hm
mhHg?
a. 75% c. 100%
b. 25% d.h 50%
5. Whathfactorsharehknownhtohinfluencehplatelethmetabolismhandhfunction?
a. Storagehtemperature c. Platelethcount
b. InitialhpH d.h Allhofhthehabove
6. Whichhofhthehfollowinghredhbloodhcellhmorphologieshmayhbehpresenthonhthehperipheralhbloodhsmearhashahresulth
ofhlosshofhRBChmembrane?
a. Spherocytes c. Burrhcells
b. Targethcells d.h Schistocytes
7. Whathdoeshthehtermhautologoushtransfusionhreferhto?
a. Ahparenthdonatinghbloodhforhhishorhherhchild
b. Anhindividualhdonatinghbloodhforhahfriend
c. Anhindividualhdonatinghbloodhforhahrelative
d. Anhindividualhdonatinghbloodhforhhishorhherhownhtransfusion
8. Whathishthehprimaryhfunctionhofhhemoglobin?
a. Ironhmetabolism c. Oxygenhtransport
b. Porphyrinhsynthesis d.h Signalhtransduction
9. Allhofhthehfollowinghareashofhredhbloodhcellhbiologyharehcrucialhforhnormalherythrocytehsurvivalh except:
a. Cellularhmetabolism. c. SitehofhthehABOhantigenhattachment.
b. RBChmembrane. d.h Hemoglobinhstructure.
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h 10.h WhathishthehcorrecthbiochemicalhcompositionhofhthehRBChmembrane?
a. 52%hprotein,h40%hlipid,h8%hcarbohydrate
b. 40%hprotein,h8%hlipid,h52%hcarbohydrate
c. 8%hprotein,h52%hlipid,h40%hcarbohydrate
d. 8%hlipid,h40%hcarbohydrate,h52%hprotein
h 11.h Allhofhthehfollowinghbiochemicalhchangesharehassociatedhwithhlosshofhredhbloodhcellhviabilityhuponhstorage
except:
a. DecreasedhpH. c. IncreasedhATPhlevel.
b. Losshofhredhbloodhcellhfunction. d.h Decreasedhglucosehconsumption.
h 12.h Whichhredhbloodhcellhpreservativehhashahstoragehtimehofh35hdays?
a. ACD c. AS-1
b. CPDA-1 d.h h CPD
h 13.h ThehRBChmembranehishrelativelyhpermeablehtohallhofhthehfollowinghexcept:
a. Chloride. c. Bicarbonate.
b. Sodium. d.h Water.
h 14.hWhathpercentagehofhplateletshishsequesteredhinhthehspleenhashfunctionalhreservehafterhbeinghreleasedhfromhtheh
bonehmarrow?
a. 30% c. 10%
b. 50% d.h h 25%
h 15.h Whathishthehmajorhbiochemicalhconsiderationhinhplatelethstorage?
a. Glucosehmetabolism c. Productionhofhcarbonhdioxide
b. Oxygenhsupply d.h RegulationhofhpH
h 16.hWhathwouldhthehhemoglobin-
oxygenhdissociationhcurvehdepicthinhahpatienthexhibitinghclinicalhsignshofhalkalosis?
a. Normal c. Shifthtohthehright
b. Shifthtohthehleft d.h Nonehofhthehabove
h 17.h Namehthehmainhlipidhcomponentshofhahredhbloodhcellhmembrane.
a. Phospholipid c. Glycolipid
b. Sphingomyelin d.h GlycophorinhA
h 18.h ThehABOhbloodhgroupshwerehdiscoveredhinh1901hbyhwhom?
a. CharleshDrew c. LoutithandhMollison
b. KarlhLandsteiner d.h EdwardhLindeman
h 19.hAhstandinghorderhofhplateletshwashshippedhtohyourhfacilityhbyhyourhsupplier.hIthwashinadvertentlyhlefthinhthehcor
nerhofhthehdepartmenthuntilhdiscoveredh36hhourshlater.hWhathwouldhthehappropriatehactionhbehforhthehbloodhban
ker?
a. Ifhthehtemperaturehinhthehboxhwash22h+/-
h2°ChandhthehplatelethswirlhseemedhOK,hithwouldhbehOKhtohaccepththehunithintohinventory.
b. Thehplateletshhavehfallenhoutsidehthehsupplier’shqualityhassurance.hThehunithshouldhbehdis
cardedhbecausehthehpHhhashprobablyhdroppedhtoohlowhandhplatelethactivationhhashbeenhco
mpromised.
c. Ifhthehtemperaturehwash1°Chtoh6°ChandhthehplatelethswirlhseemedhOK,hithwouldhbehOKhto
Thishstudyhsourcehwashdownloadedhbyh100000826342158hfromhCourseHero.comhonh09-15-2021h17:54:15hGMTh-
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accepththehunithintohinventory.
d. IfhthehplateletshappearedhOKhandhpassedhthehplatelethswirlhtesthafterhbeinghplacedhonhtheh
agitator,htheyhcouldhbehacceptedhintohthehinventory.
h 20.h Whichhmetabolichpathwayhpermitshthehaccumulationhofh2,3hdiphosphoglycerateh(2,3-DPG)?
a. Glycolysis c. Pentosehphosphatehshunt
b. Luebering-Rapoporthshunt d.h Methemoglobinhreductase
h 21.h Allhofhthehfollowingharehconsistenthwithhah"shifthtohthehright"hofhthehhemoglobin-oxygenhdissociationhcurve
except:
a. Increasedh2,3-DPG.
b. 50%hO2h saturationhtohtissues.
c. Decreasedh2,3-DPG.
d. DecreasedhhemoglobinhaffinityhforhO2.
h 22.h Whathishthehnormalhplatelethcounthrangehperhcubichmillimeter?
a. 100htoh350 c. 50,000htoh200,000
b. 150,000htoh350,000 d.h 350,000htoh500,000
h 23.h Whathcryoprotectivehagenthishaddedhtohredhbloodhcellshuponhfreezing?
a. Dextrose c. Glycerol
b. Adsol d.h Allhofhthehabove
h 24.h Ifhplateletsharehtohbehstoredhforh5hdayshonhahrotator,hwhathishthehoptimalhstoragehtemperature?
a. 1°Chtoh6°C c. 35°Chtoh37°C
b. 20°Chtoh24°C d.h 1°Chtoh10°C
h 25.h Whathrolehdohplateletshplayhinhhemostasis?
a. Maintenancehofhvascularhintegrity
b. Initialharresthofhbleedinghbyhplatelethplughformation
c. Stabilizationhofhthehhemostatichplug
d. Allhofhthehabove
h 26.h Whichhofhthehfollowinghbesthdescribesh"integral"hmembranehproteins?
a. Residehaththehcytoplasmichsurfacehofhmembrane
b. Spanhthehentirehmembranehsurface
c. Formhthehredhbloodhcellhcytoskeleton
d. Nonehofhthehabove
h 27.h Howhishstroma-freehhemoglobinhsolutionhprepared?
a. Outdatedhredhbloodhcellsharehconcentrated,handhstromahishremoved.
b. Outdatedhredhbloodhcellsharehdilutedhwithhsaline,handhstromahishremoved.
c. Outdatedhredhbloodhcellsharehlysed,handhstromahishremoved.
d. Nonehofhthehabove
h 28.h WhathishthehnormalhlifehspanhofhanhRBC?
a. 100hdays c. 120hhours
b. 120hdays d.h 2hdays
h 29.h RegardinghlosshofhRBChmembranehdeformability,hallhofhthehfollowingharehtruehexcept:
a. IncreasehinhATPhlevel.
b. DecreasehinhATPhlevel.
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