Medical Complications of Pregnancy Practice Solution Manual Fully Solved Latest Update 2025
What is the most common medical complication of pregnancy? What increases a patients risk for this
complication? - Answers Gestational Diabetes (GDM)
*5 to 9%* of all pregnancies
- Increased with obesity
How is GDM managed? What are the outcomes on infant mortality managed properly? - Answers -
*Monitoring and low fat diet*
- *Normal perinatal mortality with proper management*
How many of those with Gestational DM will turn into DM? - Answers *50%*
Diabetogenic effects of pregnancy are related to what hormone? How does it effect the fetus? - Answers
*HPL* --> Insulin resistance --> Fetal hyperglycemia and macrosomia
How does HPL affect insulin affinity in moms? - Answers HPL *reduces* insulin affinity
Low levels of what 2 factors are associated with pre-eclampsia? - Answers *Placental growth factor
(PIGF)*
*Vascular endothelial growth factor (VGF)*
What is the #1 risk factor for GDM? What risk do you carry for having GDM in your 3rd pregnancy if you
had 2 GDM pregnancy? If you had 1 GDM pregnancy and 1 NOT GDM? - Answers *Had it before*
- 1st prego + 2nd = *26x for 3rd*
- 1st prego + NOT 2nd = *6x for 3rd*
What increases your risk for GDM by 1.43x? - Answers *Smoking*
What are the ADA recommendations regarding screening for GDM? - Answers *24-28 weeks* gestation
How is one One-step (2hr) glucose tolerance testing conducted? What determines an abnormal test? -
Answers - Overnight fast for 8 hrs
*75 gm - 2 hr*
- *>140 mg* in *1* of the 3 times
How is Two-step testing preformed? How do you proceed if patients have abnormal values? - Answers
Step 1 (fasting or one hour):
, - 50 g loading
- Fasting >105 is abnormal
- One hour >140 is abnormal
Step 2 (*if abnormal*): 3-hr GTT w/100 g
*3hr:*
- Fasting >95 is abnormal
- 1hr >180
- 2 hr >155
- 3hr >140
How is the Standard Glucose Tolerance Test conducted? - Answers - Carb load (150g) for 3 days
- Fast for 8hrs
- 100 mg glucose
- Blood drawn at 1,2,3hrs
*2* abnormal values need for GDM:
- Fasting >95 is abnormal
- 1hr >180
- 2 hr >155
- 3hr >140
What is needed to confirm a diagnosis of GDM in *Standard* 3-hr GTT*? - Answers *Two abnormal
results*
What is the most common medical complication of pregnancy? What increases a patients risk for this
complication? - Answers Gestational Diabetes (GDM)
*5 to 9%* of all pregnancies
- Increased with obesity
How is GDM managed? What are the outcomes on infant mortality managed properly? - Answers -
*Monitoring and low fat diet*
- *Normal perinatal mortality with proper management*
How many of those with Gestational DM will turn into DM? - Answers *50%*
Diabetogenic effects of pregnancy are related to what hormone? How does it effect the fetus? - Answers
*HPL* --> Insulin resistance --> Fetal hyperglycemia and macrosomia
How does HPL affect insulin affinity in moms? - Answers HPL *reduces* insulin affinity
Low levels of what 2 factors are associated with pre-eclampsia? - Answers *Placental growth factor
(PIGF)*
*Vascular endothelial growth factor (VGF)*
What is the #1 risk factor for GDM? What risk do you carry for having GDM in your 3rd pregnancy if you
had 2 GDM pregnancy? If you had 1 GDM pregnancy and 1 NOT GDM? - Answers *Had it before*
- 1st prego + 2nd = *26x for 3rd*
- 1st prego + NOT 2nd = *6x for 3rd*
What increases your risk for GDM by 1.43x? - Answers *Smoking*
What are the ADA recommendations regarding screening for GDM? - Answers *24-28 weeks* gestation
How is one One-step (2hr) glucose tolerance testing conducted? What determines an abnormal test? -
Answers - Overnight fast for 8 hrs
*75 gm - 2 hr*
- *>140 mg* in *1* of the 3 times
How is Two-step testing preformed? How do you proceed if patients have abnormal values? - Answers
Step 1 (fasting or one hour):
, - 50 g loading
- Fasting >105 is abnormal
- One hour >140 is abnormal
Step 2 (*if abnormal*): 3-hr GTT w/100 g
*3hr:*
- Fasting >95 is abnormal
- 1hr >180
- 2 hr >155
- 3hr >140
How is the Standard Glucose Tolerance Test conducted? - Answers - Carb load (150g) for 3 days
- Fast for 8hrs
- 100 mg glucose
- Blood drawn at 1,2,3hrs
*2* abnormal values need for GDM:
- Fasting >95 is abnormal
- 1hr >180
- 2 hr >155
- 3hr >140
What is needed to confirm a diagnosis of GDM in *Standard* 3-hr GTT*? - Answers *Two abnormal
results*
