GENETICS EXAM #2 AND ITS
ANSWERS
The preinitiation complex forms in bacteria when the
start codon is recognized through binding of 16srRNA
and what region of mRNA?
a. Shine-Delgarno sequence
b. Kozak sequence
c. 5'-UTR
d. Poly-Adenylation site
e. CATAAT
a. Shine-Delgarno sequence
During translation initiation in eukaryotes, the amino
acid on the initiator tRNA is:
a. Acetylated methionine (aMet)
b. added using ATP as the energy source
c. methionine (Met)
d. IF-1
e. N-formylmethionine (fMet)
c. methionine (Met)
In pedigree analysis, which of the following is a key
hallmark of an autosomal dominant disorder?
a. Individuals who have the disease are commonly
born to normal (unaffected) parents
b. Each individual who has the disease has at least
, one affected parent
c. Two affected parents will not have any children with
the disease
d. Two unaffected parents always produce unaffected
children
b. Each individual who has the disease has at least one
affected parent
A mutagen has introduced a frame-shift mutation by
adding one nucleotide base. Which of the following
could be a reversion mutation for this particular
mutant?
a. deleting 2 bases only
b. adding 1 base only
c. deleting 1 base or adding 1 base
d. deleting 1 base or adding 3 bases
e. deleting 1 base or adding 2 bases
e. deleting 1 base or adding 2 bases
The mutation that causes SCD causes what kind of
change in the structure of hemoglobin?
a. decreases heme-binding ability
b. fewer chains of amino acids (trimeric rather than
tetrameric structure)
c. a single amino acid substitution that alters the
structure of the tetramer
d. addition of a single amino acid that causes a longer
protein subunit
e. loss of a single amino acid that causes a frameshift
and premature stop codon
ANSWERS
The preinitiation complex forms in bacteria when the
start codon is recognized through binding of 16srRNA
and what region of mRNA?
a. Shine-Delgarno sequence
b. Kozak sequence
c. 5'-UTR
d. Poly-Adenylation site
e. CATAAT
a. Shine-Delgarno sequence
During translation initiation in eukaryotes, the amino
acid on the initiator tRNA is:
a. Acetylated methionine (aMet)
b. added using ATP as the energy source
c. methionine (Met)
d. IF-1
e. N-formylmethionine (fMet)
c. methionine (Met)
In pedigree analysis, which of the following is a key
hallmark of an autosomal dominant disorder?
a. Individuals who have the disease are commonly
born to normal (unaffected) parents
b. Each individual who has the disease has at least
, one affected parent
c. Two affected parents will not have any children with
the disease
d. Two unaffected parents always produce unaffected
children
b. Each individual who has the disease has at least one
affected parent
A mutagen has introduced a frame-shift mutation by
adding one nucleotide base. Which of the following
could be a reversion mutation for this particular
mutant?
a. deleting 2 bases only
b. adding 1 base only
c. deleting 1 base or adding 1 base
d. deleting 1 base or adding 3 bases
e. deleting 1 base or adding 2 bases
e. deleting 1 base or adding 2 bases
The mutation that causes SCD causes what kind of
change in the structure of hemoglobin?
a. decreases heme-binding ability
b. fewer chains of amino acids (trimeric rather than
tetrameric structure)
c. a single amino acid substitution that alters the
structure of the tetramer
d. addition of a single amino acid that causes a longer
protein subunit
e. loss of a single amino acid that causes a frameshift
and premature stop codon
