ANSWERS COMPLETE AND ACCUARATE
GUIDE RATED A.
Iron is exported to the interstitial fluid or blood _____ driving force. Iron is exported
through ________, which is tightly associated with the enzyme ______.
With, ferroprotein, iron oxidase
An increase in PCSK9 activity would _______ blood cholesterol levels by _______ the
duration of _______ activity.
Increase, decreasing, LDLr
Hepcidin
Blocks ferroportin activity
What inhibits hepcidin?
Empty transferrin, loud cell signalling
What activates hepcidin?
Fully saturated transferrin, infection
An allele of ferroportin that fails to interact with Hepcidin would lead to...
Increased blood iron levels
When blood sugar levels begin to drop alpha cells secrete ______. This signal
target cells to carry out _____ and glycogenolysis.
When blood sugar levels begin to rise ______ cells secrete _______. The receptors
for this hormone are found in many cell types, but we'll focus on liver, fat and
______ cell responses.
, Cultured fat cells will import glucose at a rate that is dependent upon ______
levels in the media.
Alpha, glucagon, gluconeogenesis, beta, insulin, muscle, insulin
As blood sugar increases above fasting ______. The hormone induced ______. An
increase in muscle cell sugar uptake can also be caused by ______.
Both insulin and cellular glucose uptake levels increase, increase in sugar uptake in
fat and muscle cells is due to, muscle contractions
The enzyme that adds a phosphate to glucose to begin glycolysis in pancreatic
beta cells is called ________ . This enzyme has a _______ affinity for glucose than do
the enzymes in most of the cells of the body. This allows the phosphorylation of
sugar in beta cells to remain _______ blood sugar levels throughout the
physiological range. In muscle cells this reaction is carried out by ______, which
operates at throughout the normal physiological range _______ of blood sugar
levels.
In pancreatic beta cells aerobic respiration rate is regulated by ________ activity.
And because that is true these cells generate more _____ when blood sugar levels
rise. This in turn leads to the _____ of ______, which leads to cell ______.
Glucokinase, lower, proportional to, hexokinase, Vmax, glucokinase, ATP, inhibition,
K+ channels, depolarization
When blood sugar levels rise the _____ of KATP channels ______ beta cell
membranes, and that change in membrane potential _______ opens ______
channels. This ion then interacts with ______-containing ______, leading to insulin
secretion. An increase in uncoupler activity in these cells would lead to ________
insulin secretion in response to post prandial blood sugar levels. Notice that this
is only true becuase PFK is not the regulatory step in beta cell respiration.
Closure, depolarizes, opens, calcium, insulin, vesicles, reduced
A given taste bud cell will have _____ type(s) of tastant receptor facing the oral
cavity. When a sweet taste receptor interacts with a tastant _______ channels