MASSACHUSETTS PESTICIDE APPLICATOR CORE
EXAM LATEST 2024-2025 ACTUAL EXAM ALL 400
QUESTIONS AND CORRECT DETAILEANSWERS
WITH RATIONALES.
1. Chronic health effect Problems that de-
velop over a rela-
tively long period
of time, following
either one signifi-
cant exposure
that initiates a
prob- lem, or
following a series
of small ex-
posures which
ac- cumulate in
some manner
and result in a
development of a
disease or dis-
order
2. acute toxicity Poisoning from a
single dose over a
much shorter du-
ration of time
1 /
,3. How soon do health effects occur from accrue toxic- Within 24 hours of
ity? exposure
4. Chronic health risk problems (major examples) Mutagenicity,
oncogenicity,
carcinogenicity,
teratogenicity,
neurotoxicity
5. Mutagenicity Ability of a sub-
stance or agent
to cause muta-
tions to genes or
chromosomes
6. Changes from mutagenicity are... Almost always
harmful
2 /
,7. Tests to detect mutagenicity Varied. Tests on
cells to tests
on whole
animals
8. It's believed that chemicals that cause mutations are Cancers
more likely to be ones that can also cause...
9. Why is mutation testing used as a first screen for new Faster and cheap-
compounds? er than animal
life- time testing
10. Oncogenicity The ability of a
chemical to cause
abnormal growths
or tumors in tis-
sues
11. Carcinogenicity Ability of a sub-
stance or agent
to cause
malig- nant
tumors
12. How do they test chemicals for their ability to cause on
tumors oncogenicit
y from....
13. A rodent carcinogenicity study takes how long typi-
cally?
14. Pesticide companies are required to submit test data
3 /
, Administering dai- ly doses to ani- mals for their en- tire
lifetime and then dissecting them to detect presence of tu-
mors in the ani- mals tissues
2-3 years
Several animal species
4 /
EXAM LATEST 2024-2025 ACTUAL EXAM ALL 400
QUESTIONS AND CORRECT DETAILEANSWERS
WITH RATIONALES.
1. Chronic health effect Problems that de-
velop over a rela-
tively long period
of time, following
either one signifi-
cant exposure
that initiates a
prob- lem, or
following a series
of small ex-
posures which
ac- cumulate in
some manner
and result in a
development of a
disease or dis-
order
2. acute toxicity Poisoning from a
single dose over a
much shorter du-
ration of time
1 /
,3. How soon do health effects occur from accrue toxic- Within 24 hours of
ity? exposure
4. Chronic health risk problems (major examples) Mutagenicity,
oncogenicity,
carcinogenicity,
teratogenicity,
neurotoxicity
5. Mutagenicity Ability of a sub-
stance or agent
to cause muta-
tions to genes or
chromosomes
6. Changes from mutagenicity are... Almost always
harmful
2 /
,7. Tests to detect mutagenicity Varied. Tests on
cells to tests
on whole
animals
8. It's believed that chemicals that cause mutations are Cancers
more likely to be ones that can also cause...
9. Why is mutation testing used as a first screen for new Faster and cheap-
compounds? er than animal
life- time testing
10. Oncogenicity The ability of a
chemical to cause
abnormal growths
or tumors in tis-
sues
11. Carcinogenicity Ability of a sub-
stance or agent
to cause
malig- nant
tumors
12. How do they test chemicals for their ability to cause on
tumors oncogenicit
y from....
13. A rodent carcinogenicity study takes how long typi-
cally?
14. Pesticide companies are required to submit test data
3 /
, Administering dai- ly doses to ani- mals for their en- tire
lifetime and then dissecting them to detect presence of tu-
mors in the ani- mals tissues
2-3 years
Several animal species
4 /
