INFLAMMATION PROCESS - N5315 ADVANCED
PATHOPHYSIOLOGY EXAM QUESTIONS AND ANSWERS WITH
COMPLETE SOLUTIONS GRADED A++ LATEST UPDATE
Cellular injury
What precipitates the inflammatory process?
Mast cell degranulation, activation of the coagulation cascade, activation of the
kinin cascade, release of chemotactic factors, and the activation of the
complement cascade
What are the first 5 steps of the inflammatory process?
Functions include bacterial lysis, vasodilation and increased vascular
permeability, triggers mast cell degranulation, chemotaxis, and opsonization
What is the function of complement?
Bradykinin
What is kinin turned into?
Pain, chemotaxis, and increased vascular permeability and vasodilation
What is bradykinin responsible for?
Kinin system
What system does the coagulation cascade have a role in activating?
Factor XII (Hageman factor)
What factor activates kinin?
To form fibrin mesh to stop bleeding and to trap microorganisms
, What is the function of the coagulation cascade in the inflammatory process?
Activates complement and kinin system
What does the plasmin in the coagulation cascade do?
Neutrophils, eosinophils and monocytes
What do released chemotactic factors attract?
6-8 hours
How soon do neutrophils show up at the site of injury?
1-7 days
How soon do monocytes show up at the site of the injury?
Phagocytosis
What are neutrophils and monocytes responsible for at the site of injury?
Triggers the release of the acute phase reactants
What does the rupture of neutrophils and monocytes trigger during inflammation
process?
Mast cell degranulation
What is the most important step of the inflammatory cascade?
The additional activation of the acute phase reactants
What does mast cell degranulation lead to?
Coagulation proteins, kinin, and complement
What are the acute phase reactants?
Histamine, cytokines, leukotrienes, and prostaglandins
What 4 main items are released from mast cell degranulation?
PATHOPHYSIOLOGY EXAM QUESTIONS AND ANSWERS WITH
COMPLETE SOLUTIONS GRADED A++ LATEST UPDATE
Cellular injury
What precipitates the inflammatory process?
Mast cell degranulation, activation of the coagulation cascade, activation of the
kinin cascade, release of chemotactic factors, and the activation of the
complement cascade
What are the first 5 steps of the inflammatory process?
Functions include bacterial lysis, vasodilation and increased vascular
permeability, triggers mast cell degranulation, chemotaxis, and opsonization
What is the function of complement?
Bradykinin
What is kinin turned into?
Pain, chemotaxis, and increased vascular permeability and vasodilation
What is bradykinin responsible for?
Kinin system
What system does the coagulation cascade have a role in activating?
Factor XII (Hageman factor)
What factor activates kinin?
To form fibrin mesh to stop bleeding and to trap microorganisms
, What is the function of the coagulation cascade in the inflammatory process?
Activates complement and kinin system
What does the plasmin in the coagulation cascade do?
Neutrophils, eosinophils and monocytes
What do released chemotactic factors attract?
6-8 hours
How soon do neutrophils show up at the site of injury?
1-7 days
How soon do monocytes show up at the site of the injury?
Phagocytosis
What are neutrophils and monocytes responsible for at the site of injury?
Triggers the release of the acute phase reactants
What does the rupture of neutrophils and monocytes trigger during inflammation
process?
Mast cell degranulation
What is the most important step of the inflammatory cascade?
The additional activation of the acute phase reactants
What does mast cell degranulation lead to?
Coagulation proteins, kinin, and complement
What are the acute phase reactants?
Histamine, cytokines, leukotrienes, and prostaglandins
What 4 main items are released from mast cell degranulation?
