NURS 5334 UTA -
antimycobacterials with 100%
correct answers 2025 already
graded A+(verified & updated)
evaluation of drug sensitivity - answer -best done with sputum
culture - but this takes up to 16 weeks
-drugs are chosen by patterns of drug resistance in the community
and immunocompetence of the patient
-a new automated TB assay can identify sensitivity to rifampin in 2
hours and confirm the presence of M tuberculosis
multi-drug resistant TB (MDR TB) - answer resistant to both
isoniazid and rifampin
Extensively drug-resistant TB (XDR-TB) - answer Resistant to:
Isoniazid (INH) and rifampin
All fluoroquinolones
At least one of the injectable second-line drugs
first line treatment of TB - answer isoniazid, rifampin, pyrazinamide,
and ethambutol
rifapentine and rifabutin are also considered to be first line
two phases of TB treatment - answer induction phase: lasts about 8
weeks, eliminate actively dividing tubercle bacilli
, continuation phase: lasts from 18 weeks to 24 months, eliminate
intracellular "persisters"
drug sensitive TB treatment - answer -8 weeks induction with
isoniazid, rifampin, pyrazinamide, ethambutol
-continuation 18 weeks with isoniazid and rifampin
isoniazid-resistant TB treatment - answer rifampin, ethambutol, adn
pyrazinamide for 6 months
rifampin-resistant TB treatment - answer isoniazid, ethambutol, adn
pyrazinamide for 18-24 months
MDR-TB and XDR-TB treatment - answer 24 months with second and
third line drugs
poor prognosis
patients with TB plus HIV infection - answer -more aggressive
therapy
-minimum 6 months of treatment
-rifampin accelerates metabolism of antiretroviral drugs and
decreases their effects
promoting drug adherence - answer -directly observed therapy
(DOT) - also allows for ongoing assessment of clinical signs
-intermittent dosing - 2 or 3 times a week
latent tuberculosis tests - answer TB skin test
Interferon Gamma Release Assays
antimycobacterials with 100%
correct answers 2025 already
graded A+(verified & updated)
evaluation of drug sensitivity - answer -best done with sputum
culture - but this takes up to 16 weeks
-drugs are chosen by patterns of drug resistance in the community
and immunocompetence of the patient
-a new automated TB assay can identify sensitivity to rifampin in 2
hours and confirm the presence of M tuberculosis
multi-drug resistant TB (MDR TB) - answer resistant to both
isoniazid and rifampin
Extensively drug-resistant TB (XDR-TB) - answer Resistant to:
Isoniazid (INH) and rifampin
All fluoroquinolones
At least one of the injectable second-line drugs
first line treatment of TB - answer isoniazid, rifampin, pyrazinamide,
and ethambutol
rifapentine and rifabutin are also considered to be first line
two phases of TB treatment - answer induction phase: lasts about 8
weeks, eliminate actively dividing tubercle bacilli
, continuation phase: lasts from 18 weeks to 24 months, eliminate
intracellular "persisters"
drug sensitive TB treatment - answer -8 weeks induction with
isoniazid, rifampin, pyrazinamide, ethambutol
-continuation 18 weeks with isoniazid and rifampin
isoniazid-resistant TB treatment - answer rifampin, ethambutol, adn
pyrazinamide for 6 months
rifampin-resistant TB treatment - answer isoniazid, ethambutol, adn
pyrazinamide for 18-24 months
MDR-TB and XDR-TB treatment - answer 24 months with second and
third line drugs
poor prognosis
patients with TB plus HIV infection - answer -more aggressive
therapy
-minimum 6 months of treatment
-rifampin accelerates metabolism of antiretroviral drugs and
decreases their effects
promoting drug adherence - answer -directly observed therapy
(DOT) - also allows for ongoing assessment of clinical signs
-intermittent dosing - 2 or 3 times a week
latent tuberculosis tests - answer TB skin test
Interferon Gamma Release Assays
