Tietz Fundamentals Of
d d
CLINICAL CHEMISTRY AND
d d d
MOLECULAR DIAGNOSTICS d
7th Edition By Carl A. Burtis
d d d d d
TEST BANK d
,TietzdFundamentalsdofdClinicaldChemistrydanddMoleculardDiagnosticsd7thd EditiondTestdBank
Tabledofdcontents:
I.dPrinciplesdOfdLaboratorydMedicine
Chapterd1.dClinicaldChemistry,dMoleculardDiagnostics,danddLaboratorydMedicine
Chapterd2.dSelectiondanddAnalyticaldEvaluationdofdMethodsd—dWithdStatisticaldTechniques
Chapterd3.dClinicaldEvaluationdofdMethods
Chapterd4.dEvidence-BaseddLaboratorydMedicine
Chapterd5.dEstablishmentdanddUsedofdReferencedValues
Chapterd6.dSpecimendCollection,dProcessing,danddOtherdPreanalyticaldVariables
Chapterd7.dQualitydManagement
II.dAnalyticaldTechniquesdAnddInstrumentation
Chapterd8.dPrinciplesdofdBasicdTechniquesdanddLaboratorydSafety
Chapterd9.dOpticaldTechniques
Chapterd10.dElectrochemistrydanddChemicaldSensors
Chapterd11.dElectrophoresis
Chapterd12.dChromatography
Chapterd13.dMassdSpectrometry
Chapterd14.dEnzymedanddRatedAnalyses
Chapterd15.dImmunochemicaldTechniques
Chapterd16dAutomation
Chapterd17.dPoint-of-CaredInstrumentation
III.d Analytes
Chapterd18.dAminodAcids,dPeptides,danddProteins
Chapterd19.dSerumdEnzymes
Chapterd20.dTumordMarkersdanddCancerdGenes
Chapterd21.dKidneydFunctiondTestsd—dCreatinine,dGFR,dUrea,danddUricdAcid
Chapterd22.dCarbohydrates
Chapterd23.dLipids,dLipoproteins,dApolipoproteins,danddOtherdCardiacdRiskdFactors
Chapterd24.dElectrolytesdanddBlooddGases
Chapterd25.dHormones
Chapterd26.d CatecholaminesdanddSerotonin
Chapterd27.d Vitamins,dTracedElements,dNutritionaldAssessment
Chapterd28.dHemoglobin,dIron,danddBilirubin
Chapterd29.dPorphyrinsdanddPorphyrias
Chapterd30.dTherapeuticdDrugsdanddTheirdManagement
Chapterd31.dClinicaldToxicology
Chapterd32.d ToxicdMetals
IV.d Pathophysiology
Chapterd33.dDiabetes
,Chapterd34.d CardiovasculardDisease
Chapterd35.dKidneydDisease
Chapterd36.d PhysiologydanddDisordersdofdWater,dElectrolyte,danddAcid-BasedMetabolism
Chapterd37.ddLiverdDisease
Chapterd38.d GastrointestinaldanddPancreaticdDiseases
Chapterd39.d DisordersdofdBonedanddMineraldMetabolism
Chapterd40.d DisordersdofdthedPituitarydGland
Chapterd41.d DisordersdofdthedAdrenaldCortex
Chapterd42.d ThyroiddDisorders
Chapterd43.d Reproduction-RelateddDisorders
Chapterd44.ddPregnancydanddPrenataldTesting
Chapterd45.d NewborndScreeningdandd InborndErrorsdofdMetabolism
Chapterd46.dPharmacogenetics
V.d MoleculardDiagnostics
Chapterd47.dPrinciplesdofdMoleculardBiology
Chapterd48.dNucleicdAciddTechniquesdanddApplications
Chapterd49.dGenomesdanddNucleicdAciddAlterations
, TietzdFundamentalsdofdClinicaldChemistrydanddMolecularDiagnostics,d7edBurtisdTestdBank
Chapterd01:dClinicaldChemistry,dMoleculardDiagnostics,danddLaboratorydMedicineTestd
Bank
MULTIPLEdCHOICE
1. Andindividualdworkingdindadclinicaldchemistrydlaboratorydisdmarrieddtodadsalesdrepresentativedw
hodworksdfordadcompanydthatdsellsdchemistrydlaboratorydsupplies.dWhendthedlaboratorydmanage
rdrequestsdadlistdofdneededdsupplies,dcostdofdsupplies,danddvendors,dthisdindividualdonlydrecomme
ndsdthedspouse’sdcompanydasdthedvendor.dThisdisdconsidereddtodbeda(n):
a. accountingdissue.
b. possibledconflictdofdinterest.
c. maintenancedofdconfidentialitydissue.
d. problemdwithdresourcedallocation.
ANS:d B
Concerndhasdbeendraiseddoverdthedinterrelationshipsdbetweendpractitionersdindthedmedicaldfieldda
nddcommercialdsuppliersdofddrugs,ddevices,dequipment,detc.,dtodthedmedicaldprofession.
Similarly,drelationshipsdhavedbeendscrutinizeddbetweendclinicaldlaboratoriansdanddmanufacturer
sdanddprovidersdofddiagnosticdequipmentdanddsupplies.dThesedconcernsdleddthedNationaldInstitute
sdofdHealthd(NIH)dind1995dtodrequiredofficialdinstitutionaldreviewdofdfinancialddisclosuredbydresea
rchersdanddmanagementdofdsituationsdindwhichddisclosuredindicatesdpotentialdconflictsdofdinterest.
DIF: 1 REF:dddPaged4-5 OBJ:d 6d|d7
2. Adpatientdvisitsdherdphysiciandstatingdthatdherdprescribeddpainkillerdisdnotdworkingdtodreducedt
hedpaindfollowingdherdrecentdsurgery.dAdfrienddofdthedpatientdclaimsdthatdthedsamedpainkillerd“
workeddwonders”dtodreducedherdpaindafterdthedsamedsurgery.dThedphysiciandstatesdthatdtheddiff
erencedindthedeffectdofdtheddrugdmightdbedcauseddby
,dwhichdisdstudieddindpharmacogenetics.
a. epidemiology
b. andinheritedddisease
c. adconflictdofdinterest
d. adgeneticdvariationdinddrug-metabolizingdenzymes
ANS:d D
Pharmacogeneticsdisdthedstudydofdthedgeneticdvariationdofddrugdmetabolismdbetweendi
ndividuals.
DIF: 1 REF:dddPaged3 OBJ:d 1
3. Johndworksdindadmolecularddiagnosticsdlaboratorydanddreceivesdadblooddsampledthatdhasdthedn
amedofdadclosedfrienddprinteddondthedbar-
codeddlabel.dThedgeneticdtestdthatdisdordereddondthedfriend’sdsampledwoulddprovideddiagnosticd
informationdaboutdaddisorderdthatdhasdadpoordprognosis,danddthedtestdisdusuallydperformeddbydJ
ohn.dHedasksdadfellowdemployeedtodanalyzedthedsampledfordhimdanddnotddivulgedthedresults.dTh
isdethicaldissuedconcerns:
a. confidentialitydofdpatientdgeneticdanddmedicaldinformation.
b. adconflictdofdinterest.
c. resourcedallocation.
d. diagnosticdaccuracy.