Final Exam: NU664C / NU 664C
(Latest Update ) Family
Psychiatric Mental Health I | Test
Questions & Answers | Grade A |
100% Correct (Verified Answers) -
Regis
Question:
SSRIs and other serotonergic antidepressants are effective in the treatment of
Answer:
depression, other data indicate that serotonin is involved in the
pathophysiology of depression
Question:
Depletion of serotonin may
Answer:
precipitate depression, and some patients with suicidal impulses have low
cerebrospinal fluid (CSF) concentrations of serotonin metabolites and low
concentrations of serotonin uptake sites on platelets.
,Question:
Although norepinephrine and serotonin are the biogenic amines most often
associated with the pathophysiology of depression,
Answer:
dopamine has also been theorized to play a role. The data suggest that
dopamine activity may be reduced in depression and increased in mania
Question:
Drugs that reduce dopamine concentrations—for example, reserpine
(Serpasil)—
Answer:
and diseases that reduce dopamine concentrations (e.g., Parkinson's disease)
are associated with depressive symptoms
Question:
Drugs that increase dopamine concentrations
Answer:
such as tyrosine, amphetamine, and bupropion (Wellbutrin), reduce the
symptoms of depression
,Question:
Two recent theories about dopamine and depression are that
Answer:
the mesolimbic dopamine pathway may be dysfunctional in depression and
that the dopamine D1 receptor may be hypoactive in depression
Question:
Neurotransmitter Disturbances Acetylcholine (ACh) Abnormal levels of
choline, which is a precursor to ACh, have been found at
Answer:
autopsy in the brains of some depressed patients, perhaps reflecting
abnormalities in cell phospholipid composition
Question:
Reductions of GABA have been observed in
Answer:
CSF, and brain GABA levels in depression. Animal studies have also found
that chronic stress can reduce and eventually can deplete GABA levels. By
contrast, GABA receptors are upregulated by antidepressants, and some
GABAergic medications have weak antidepressant effects
, Question:
Serotonin syndrome
Answer:
Concurrent administration of an SSRI with an MAOI, Ltryptophan, or lithium
(Eskalith) can raise plasma serotonin concentrations to toxic levels, producing
a constellation of symptoms called serotonin syndrome.
Question:
This serious and possibly fatal syndrome of serotonin overstimulation
comprises, in order of appearance as the condition worsens
Answer:
(1) diarrhea;
(2) restlessness;
(3) extreme agitation, hyperreflexia, and autonomic instability with possible
rapid fluctuations in vital signs;
(4) myoclonus, seizures, hyperthermia, uncontrollable shivering, and rigidity;
(5) delirium, coma, status epilepticus, cardiovascular collapse, and death.
(Latest Update ) Family
Psychiatric Mental Health I | Test
Questions & Answers | Grade A |
100% Correct (Verified Answers) -
Regis
Question:
SSRIs and other serotonergic antidepressants are effective in the treatment of
Answer:
depression, other data indicate that serotonin is involved in the
pathophysiology of depression
Question:
Depletion of serotonin may
Answer:
precipitate depression, and some patients with suicidal impulses have low
cerebrospinal fluid (CSF) concentrations of serotonin metabolites and low
concentrations of serotonin uptake sites on platelets.
,Question:
Although norepinephrine and serotonin are the biogenic amines most often
associated with the pathophysiology of depression,
Answer:
dopamine has also been theorized to play a role. The data suggest that
dopamine activity may be reduced in depression and increased in mania
Question:
Drugs that reduce dopamine concentrations—for example, reserpine
(Serpasil)—
Answer:
and diseases that reduce dopamine concentrations (e.g., Parkinson's disease)
are associated with depressive symptoms
Question:
Drugs that increase dopamine concentrations
Answer:
such as tyrosine, amphetamine, and bupropion (Wellbutrin), reduce the
symptoms of depression
,Question:
Two recent theories about dopamine and depression are that
Answer:
the mesolimbic dopamine pathway may be dysfunctional in depression and
that the dopamine D1 receptor may be hypoactive in depression
Question:
Neurotransmitter Disturbances Acetylcholine (ACh) Abnormal levels of
choline, which is a precursor to ACh, have been found at
Answer:
autopsy in the brains of some depressed patients, perhaps reflecting
abnormalities in cell phospholipid composition
Question:
Reductions of GABA have been observed in
Answer:
CSF, and brain GABA levels in depression. Animal studies have also found
that chronic stress can reduce and eventually can deplete GABA levels. By
contrast, GABA receptors are upregulated by antidepressants, and some
GABAergic medications have weak antidepressant effects
, Question:
Serotonin syndrome
Answer:
Concurrent administration of an SSRI with an MAOI, Ltryptophan, or lithium
(Eskalith) can raise plasma serotonin concentrations to toxic levels, producing
a constellation of symptoms called serotonin syndrome.
Question:
This serious and possibly fatal syndrome of serotonin overstimulation
comprises, in order of appearance as the condition worsens
Answer:
(1) diarrhea;
(2) restlessness;
(3) extreme agitation, hyperreflexia, and autonomic instability with possible
rapid fluctuations in vital signs;
(4) myoclonus, seizures, hyperthermia, uncontrollable shivering, and rigidity;
(5) delirium, coma, status epilepticus, cardiovascular collapse, and death.
