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h L L
Michelle J. Willihnganz, Samuel L. Gurevitz, Bruce Clayton Complete
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,Chapter 01: Drug Definitions, Standards, and Information Sources Willihnganz
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: Clayton’s Basic Pharmacology for Nurses, 19th Edition
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MULTIPLELCHOICE
1. WhichLnameLidentifiesLaLdrug listedLbyLtheLUSLFoodLan
hi
LdDrugLAdministrationL(FDA)?
hi
a. Brand
b. Nonproprietary
c. Official
d. Trademark
ANS:L C
TheLofficialLnameLisLtheLnameLunderLwhichLaLdrugLisLlistedLb
yLtheLFDA.LTheLbrandLname,LorLtrademark,LisLtheLnameLgivLe
nLtoLaLdrugLbyLitsLmanufacturer.LTheLnonproprietary,LorLgenLe
ric,LnameLisLprovidedLbyLtheLUnitedLStatesLAdoptedLNamesL
Council.
DIF: CognitiveLLevel:LKnowledge REF:L p.L 9
OBJ:L1NAT:LNCLEXLClientLNeedsLCategory:LSafe,LEffectiveLCarLeEnviron hi
mentLTOP:LLLLNursingLProcessLStep:LAssessment
CON:
PatientL Education
2. WhichLsourceLcontainsLinformationLspecificLtoLnutritionalLsupplements?
a. USPLDictionaryLofL USANL &InternationalL DrugLNames
b. NaturalLMedicinesLComprehensiveLDatabase
c. UnitedLStatesLPharmacopoeia/NationalLFormularyL(USPNF)
d. DrugLInteractionLFacts
ANS:L C
UnitedLStatesLPharmacopoeia/NationalLFormularyLcontainsLinformationLspecificLtoLnutritionalLs hi
upplements.LUSPLDictionaryLofLUSANL &LInternationalLDrugLNamesLisLaLcompilationLofLdrugLn hi
ames,LpronunciationLguide,LandLpossibleLfutureLFDALapprovedLdrugs;LitLdoesLnotLincludeLnutLri
tionalLsupplements.L NaturalLMedicinesLComprehensiveLDatabaseLcontains
evidence-
basedLinformationLonLherbalLmedicinesLandLherbalLcombinationLproducts;LitLdoesLnotincludeLinf
hi
LormationLspecificLtoLnutritionalLsupplements.LDrugLInteractionLFactsLcontainsLcomprehensiv
eLinformation onLdrugL interactionLfacts;LitL doesLnotL includeLnutritionalLsupplements.
hi
DIF:LLL CognitiveLLevel:LKnowledge REF:LLL p.L4
OBJ:L3NAT:LL NCLEXLClientL NeedsL Category:LPhysiologicalLInte
hi
grity
TOP: Nursing ProcessLStep:LAssessment CON:LLLNutritionL|LPatientL Education
hi
3. Which drug referenceLcontainsLdrugLmonographsLthatLdescribeLallLdrugsLinLaLtherapeuticLclass?
hi hi
a. DrugLFactsLandLComparisons
,TestLBankL ForL Clayton’sL BasicLPharmacologyLforL NursesL 19thL Editi 3
o
b. DrugLInteractionLFacts
c. Handbook onLInjectableLDrugs hi
d. Martindale—TheLCompleteLDrugLReference
ANS:L A
DrugLFactsLandLComparisonsLcontainsLdrugLmonographsLthatLdescribeLallLdrugsLinLatL hi
herapeuticLclass.LMonographsLareLformattedLasLtablesLtoLallowLcomparisonLofsimilarprL
oducts,LbrandLnames,Lmanufacturers,LcostLindices,LandLavailableLdosageLformsLOnlineL
versionLisLavailable.
DIF: CognitiveLLevel:LKnowledge REF:LLLp.L 4 TableL1.2 hi
OBJ: 3 NAT:LL NCLEX Client Needs Category:LPhysiologicalLIntegrity
hi hi hi
TOP: Nursing ProcessLStep:LAssessment CON:LLLSafetyL|PatientL EducationL|ClinicalLJudgment
hi
4. WhichLdrug referenceL containsL monographsLaboutL virtuallyLeverysingle-
hi
Lentitydrug availableinLtheLUnitedLStatesLandLdescribesLtherapeuticLusesLofLdrugs,LincludingLa
hi hi
LpprovedLandLunapprovedLuses?
a. Martindale:LTheLCompleteLDrug Reference hi
b. AHFSLDrugLInformation
c. DrugL Reference
d. DrugLFactsLandLComparisons
ANS:L B
AHFSLDrugLInformationLcontainsLmonographsLaboutLvirtuallyLeveryLsingle-
entityLdrugLavailableLinLtheLUnitedLStatesLandLdescribesLtherapeuticLusesLofLdrugs,L includingLapL
provedLandunapprovedLuses.
hi
DIF: CognitiveLLevel:LKnowledge REF:LLLp.L 4 TableL1.2 hi
OBJ: 3 NAT:LL NCLEX Client NeedsLCategory:LPhysiologicalLIntegrity
hi hi
TOP: NursingLProcessLStep:LPlanning CON:L SafetyL|PatientL EducationL|ClinicalLJudgment
5. WhichLonlineLdrugLreferenceLmakesLavailableLtoLhealthcareLprovidersLand theLpublicLaLsta
hi
Lndard,Lcomprehensive,Lup-to-dateLlookLupLandLdownloadableLresourceLaboutLmedicines?
a. AmericanLDrugLIndex
b. AmericanL HospitalL Formulary
c. DailyMed
d. DrugLReference
ANS:L C
DailyMedLmakesLavailableLto healthcareLprovidersLandLtheLpublicLaLstandard,Lcomprehensive,L
hi hi
up-to-
dateLlookLupLandLdownloadableLresourceLaboutLmedicines.LTheLAmericanLDrugLIndexLisnotLapLpr hi
opriateLforLpatientLuse.LTheLAmericanLHospitalLFormularyLisLnotLappropriateLforLpatientL us
e. TheLdrugLreferenceL isL notL appropriateLforLpatientL use.
DIF: CognitiveLLevel:LKnowledge REF: p.L3L |Lp.L4
OBJ:L3NAT:LL NCLEXLClientL NeedsL Category:LPhysiologicalLInte
hi
grity
TOP:LLNursing ProcessLStep:LImplementation
hi
CON:L SafetyL|PatientLEducationL|LClinicalLJudgment
6. WhichLlegislationLauthorizesLtheLFDALtoLdetermineLtheLsafetyofLaLdrugLbeforeLitsLmarketing?
a. FederalLFood,LDrug,LandLCosmeticLActL(1938)
b. DurhamLHumphreyLAmendmentL (1952)
, TestLBankL ForL Clayton’sL BasicLPharmacologyLforL NursesL 19thL Editi 4
o
c. ControlledLSubstancesLAct (1970) hi
d. KefauverLHarrisLDrug AmendmentL(1962)
hi
ANS:L A
TheLFederalLFood,LDrug,LandLCosmeticLActLofL1938LauthorizedLtheLFDALtoLdetermineLtheLsafL
etyLofLallLdrugsLbeforeLmarketing.LLaterLamendmentsLandLactsLhelpedLtightenLFDALcontrolLanL
dLensureLdrugLsafety.LTheLDurhamLHumphreyLAmendmentLdefinesLtheLkindsLofLdrugsLthatLcanL
notLbeLusedLsafelyLwithoutLmedicalLsupervisionLandLrestrictsLtheirLsaleLtoLprescriptionLbyLaLlicL
ensedLpractitioner.LTheLControlledLSubstancesLActLaddressesLonlyLcontrolledLsubstancesLandthL hi
eirLcategorization.LTheLKefauverLHarrisLDrugLAmendmentLensuresLdrugLefficacyLandLgreaterdrL
ugLsafety.LDrugLmanufacturersLareLrequiredLtoLproveLtoLtheLFDALtheLeffectivenessLofLtheirLpro
LductsLbeforeL marketingLthem.
DIF: CognitiveLLevel:LKnowledge
REF:Lp.L5LTableLl.3LOBJ: 5
NAT:LNCLEXLClientLNeedsLCategory:LPhysiologicalLIntegri
tLyTOP:L NursingLProcessL Step:LAssessment
CON:L SafetyL|PatientL EducationL|LEvidenceL|LHealthLCareLLaw
7. WhichLclassificationLdoesLmeperidineL(Demerol)LfallLunder?
a. I
b. II
c. III
d. IV
ANS:L B
MeperidineL(Demerol)LisLa ScheduleLIILdrug;LitLhasLaLhighLpotentialLforLabuseLandLmayLleadLtoL
hi hi
severeLpsychologicalLandLphysicalLdependence.LScheduleLI drugsLhaveLhighLpotentialLforLabuseLa
hi hi
ndLnoLrecognizedLmedicalLuse.LScheduleLIIILdrugsLhaveLsomeLpotentialLforLabuse.LUseLmayLlLe
adLtoLlowLtoLmoderateLphysicalLdependenceLorLhighLpsychologicalLdependence.LScheduleLIVLd
rugsLhaveLlowLpotentialLforLabuse.LUseLmayLleadLtoLlimitedLphysicalLorLpsychologicalLdepenLd
ence.
DIF: CognitiveLLevel:LKnowledge REF: p.L10
OBJ:L2NAT:LLNCLEXLClientLNeedsLCategory:LSafe,LEffectiveLCar
hi
LeLEnvironment
TOP: NursingLProcessLStep:LAssessment CON:L PatientL EducationL|AddictionL|Pain
8. WhichLactionLwouldLtheLFDALtakeLtoLexpediteLdrugLdevelopmentL andLapprovalLforLanLoutbreakL hi
ofLsmallpox?
a. ListLsmallpoxLasLaLhealthLorphan disease. hi
b. OmitLthe preclinicalLresearchLphase.
hi
c. ExtendLtheLclinical researchLphase.
hi
d. FastLtrackLthe investigationalLdrug.
hi
ANS:L D
OnceLtheLInvestigationalLNewLDrugLApplicationLhasLbeenLapproved,LtheLdrugLcanLreceiveLhigL
hestLpriorityLwithinLtheLagency,LwhichLisLcalledLfastLtracking.LALsmallpoxLoutbreakLwouldLbec
LomeLaLpriorityLconcernLinLtheLworld.LOrphanLdiseasesLareLnotLresearched LinLaLpriorityLmanner
.LPreclinicalLresearchLisLnotLomitted.LExtendingLanyLphaseLofLtheLresearchLwouldLmeanaLlonger
hi
LtimeLtoLdevelopLaLvaccine.LTheLFDALmustLensureLthatLallLphasesLofLtheLpreclinicalLandclinicalLr
hi
eLsearchLphaseL haveL beenLcompletedLinLaLsafeLmanner.
DIF:L L CognitiveLLevel:LKnowledge REF:LLL p.L7 OBJ:L 5