NR 507 MIDTERM EXAM 2 LATEST
VERSIONS MIDTERM ADVANCED
PATHOPHYSIOLOGY MIDTERM EXAM
LATEST CHAMBERLAINE
Hives (urticaria) are an example of a: - answer Type 1 hypersensitivity reaction.
Anaphylaxis is what type of reaction? - answer type 1 hypersensitivity
Which of the following are considered the "first responders" of the innate immune
system? – answer neutrophils
Allergic contact dermatitis is an example of what type of
hypersensitivity reaction. – answer type 4 hypersensitivity reaction
Type 2 (Cytotoxic) hypersensitivity reactions are mediated by: - answer IgG or IgM
Type 1 hypersensitivity reaction is mediated by – answer IgE
Allergic asthma is an example of – answer type 1 hypersensitivity reaction
type 2 hypersensitivity – answer tissue specific
Primary effector cells of type 2 - answer macrophages
Examples of type 2 reactions - answer drug allergies, hemolytic anemia, blood
transfusion mismatch, allergies against infectious agents
Type 2 causes - answer The cell to be destroyed by the antibody
Cell destruction through phagocytosis by macrophages
Damage to the cell by neutrophils triggering phagocytosis
Natural killer cells to release toxic substances that destroy the target cell
Malfunction of the cell without destruction
Type 3 hypersensitivity reaction - answer antigen-antibody response
,Where does the antibody bind to the antigen in type 3 response? - answer in blood or
body fluids and then circulates to tissue
Where does the antibody bind to the antigen in type 1, 2, and 4? - answer on cell
surface
Primary effector cell in type 3 - answer neutrophils
example of type 3 reaction - answer serum sickness
type 4 hypersensitivity reaction - answer cell-mediated response
primary mediators of type 4 - answer lymphocytes and macrophages
type 4 mediated by – answer T lymphocytes and do not use antibodies
example of type 4 - answer localized contact dermatitis (poison ivy)
Damage occurs with ABO incompatibility because: - answer Complement damages
RBC membrane causing cell lysis.
Which of the following is the underlying pathology for hay fever? - answer mast cell
degranulation
The diagnosis for an individual who presents to the office with sudden swollen lips and
eyes, shortness of breath and throat tightness after a bee sting is: - answer anaphylaxis
Which of the following assessment findings would be expected in a patient who
presents with urticaria? - answer Eosinophilia.
An example of a primary immunodeficiency is: - answer Chronic Granulomatous
Disease.
what is a predominant cause of secondary immune deficiencies worldwide. - answer
Malnutrition
Which of the following is an autoimmune disease? - answer Systemic Lupus
Erythematosus (SLE).
, Which is true about a primary immunodeficiency? - Answer It is the result of a single
gene defect. (genetics)
Examples of secondary immunodeficiency – answer HIV, cancer
Secondary immunodeficiency caused by - answer external to immune system
Examples of primary immunodeficiency - answer Chronic granulomatous Disease of
Childhood
DiGeorge Syndrome
Familial Mediterranean fever
Job Syndrome
Common Variable Immunodeficiency
examples of secondary immunodeficiency - answer Human Immunodeficiency Virus
Pneumocystis Carinii
Pneumonia
Sinus infection
Lung cancer
Select the best statement below that describes a primary immunodeficiency: - answer
Are less common and occur due to a defect on the development of the immune system.
Cancer is a secondary immunodeficiency. - Answer true
Sinusitis is considered a primary immunodeficiency. - answer false
A patient with human immunodeficiency virus (HIV) was admitted to the acute care
facility with difficulty breathing. He is diagnosed with Pneumocytis carinii. Pneumocystis
carinii an example of: - answer secondary immune disease
Which of the following findings can be used to diagnose Systemic Lupus Erythematosus
(SLE)? - answer Facial rash confined to the cheeks.
A renal disease most often associated with autoimmunity is - answer
Glomerulonephritis.
The major immune system change associated with Sjogren's Syndrome is: - answer
Autoantibodies and auto-reactive T-cells against apoptotic cells.
VERSIONS MIDTERM ADVANCED
PATHOPHYSIOLOGY MIDTERM EXAM
LATEST CHAMBERLAINE
Hives (urticaria) are an example of a: - answer Type 1 hypersensitivity reaction.
Anaphylaxis is what type of reaction? - answer type 1 hypersensitivity
Which of the following are considered the "first responders" of the innate immune
system? – answer neutrophils
Allergic contact dermatitis is an example of what type of
hypersensitivity reaction. – answer type 4 hypersensitivity reaction
Type 2 (Cytotoxic) hypersensitivity reactions are mediated by: - answer IgG or IgM
Type 1 hypersensitivity reaction is mediated by – answer IgE
Allergic asthma is an example of – answer type 1 hypersensitivity reaction
type 2 hypersensitivity – answer tissue specific
Primary effector cells of type 2 - answer macrophages
Examples of type 2 reactions - answer drug allergies, hemolytic anemia, blood
transfusion mismatch, allergies against infectious agents
Type 2 causes - answer The cell to be destroyed by the antibody
Cell destruction through phagocytosis by macrophages
Damage to the cell by neutrophils triggering phagocytosis
Natural killer cells to release toxic substances that destroy the target cell
Malfunction of the cell without destruction
Type 3 hypersensitivity reaction - answer antigen-antibody response
,Where does the antibody bind to the antigen in type 3 response? - answer in blood or
body fluids and then circulates to tissue
Where does the antibody bind to the antigen in type 1, 2, and 4? - answer on cell
surface
Primary effector cell in type 3 - answer neutrophils
example of type 3 reaction - answer serum sickness
type 4 hypersensitivity reaction - answer cell-mediated response
primary mediators of type 4 - answer lymphocytes and macrophages
type 4 mediated by – answer T lymphocytes and do not use antibodies
example of type 4 - answer localized contact dermatitis (poison ivy)
Damage occurs with ABO incompatibility because: - answer Complement damages
RBC membrane causing cell lysis.
Which of the following is the underlying pathology for hay fever? - answer mast cell
degranulation
The diagnosis for an individual who presents to the office with sudden swollen lips and
eyes, shortness of breath and throat tightness after a bee sting is: - answer anaphylaxis
Which of the following assessment findings would be expected in a patient who
presents with urticaria? - answer Eosinophilia.
An example of a primary immunodeficiency is: - answer Chronic Granulomatous
Disease.
what is a predominant cause of secondary immune deficiencies worldwide. - answer
Malnutrition
Which of the following is an autoimmune disease? - answer Systemic Lupus
Erythematosus (SLE).
, Which is true about a primary immunodeficiency? - Answer It is the result of a single
gene defect. (genetics)
Examples of secondary immunodeficiency – answer HIV, cancer
Secondary immunodeficiency caused by - answer external to immune system
Examples of primary immunodeficiency - answer Chronic granulomatous Disease of
Childhood
DiGeorge Syndrome
Familial Mediterranean fever
Job Syndrome
Common Variable Immunodeficiency
examples of secondary immunodeficiency - answer Human Immunodeficiency Virus
Pneumocystis Carinii
Pneumonia
Sinus infection
Lung cancer
Select the best statement below that describes a primary immunodeficiency: - answer
Are less common and occur due to a defect on the development of the immune system.
Cancer is a secondary immunodeficiency. - Answer true
Sinusitis is considered a primary immunodeficiency. - answer false
A patient with human immunodeficiency virus (HIV) was admitted to the acute care
facility with difficulty breathing. He is diagnosed with Pneumocytis carinii. Pneumocystis
carinii an example of: - answer secondary immune disease
Which of the following findings can be used to diagnose Systemic Lupus Erythematosus
(SLE)? - answer Facial rash confined to the cheeks.
A renal disease most often associated with autoimmunity is - answer
Glomerulonephritis.
The major immune system change associated with Sjogren's Syndrome is: - answer
Autoantibodies and auto-reactive T-cells against apoptotic cells.
