NURS 5315 UTA EXAM 2 2025| BRAND NEW
ACTUAL EXAM WITH 100% VERIFIED
QUESTIONS AND CORRECT SOLUTIONS|
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Type 2 hypersensitivity - correct answer - E. Antibodies directed against
fixed antigens on the plasma membrane of cells
C.M. Varies depending on alloimmune or autoimmune
Alloimmunity and example of hypersensitivity - correct answer - When an
individuals immune system reacts against antigens on the tissues of other
members of the same species
Blood transfusions- causes clumping and lysis of RBC- fever, nausea,
chills, low back pain, dark urine, hives, itching, SOB
Rh incompatibility- hemolytic disease of newborn with jaundice, give
Rhogam within 72 hours of birth (Rh- mother with Rh+ child)
Autoimmunity and example of hypersensitivity - correct answer - A
breakdown of tolerance in which the bodies immune system begins to
recognize self-antigens as foreign.
Graves Disease- autoantibodies form against thyroid cells- bind to thyroid
cells and mimic action of TSH, increases secretion of thyroxine
Myasthenia Gravis- autoantibodies against acetylcholine bind to the post
synaptic receptors and inhibit synaptic transmission of acetylcholine. Leads
to muscle weakness and paralysis (mind to ground)
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Guillain-Barre' syndrome- antibodies bind with myelin sheath of the
peripheral nervous system, triggering the immune response. Causes
demyelination of the peripheral nerves and a rapidly progressive,
ascending paralysis (ground to brain)
Type III hypersensitivity - correct answer - Widespread immune and
inflammatory response not specified for any cell or tissue. SLE, RA
Antibodies are formed against and bind to circulating antigens, antigen-
antibody complex deposits in vessel walls or tissue. Causes cellular and
tissue damage. IgG and IgM response, spread via circulation- not specific
to a cell or tissue- widespread damage.
Type IV hypersensitivity - correct answer - T-cell lymphocyte mediated
reaction that does not require antibody activation. Delayed response- 24-72
hours.
Contact dermatitis- poison ivy, topical drugs, chemicals such as nickel or
formaldehyde. Antigens too small to cause a reaction bind to proteins,
response includes rash, red bumps, itching, and blisters.
Reactive tuberculin test- PPD cause and induration in 24-72 if person was
previously exposed to tuberculin antigen
Solid organ transplant rejection- 11-14 days after 1st exposure, 5-6 days
after 2nd exposure, results in mononuclear infiltration, decreased
circulation, and tissue necrosis.
Systemic Lupus Erythematosus - correct answer - E. Primarily women
aged 20-40, Type III hypersensitivity. Antibodies are formed against DNA
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Genetic, leads to tissue damage. Exacerbated by infections, UV light,
estrogen, meds, stress
Diagnosed by serum ANA
C.M. Butterfly rash (cheeks), photosensitivity, nonerosive arthritis of at least
2 peripheral joints, inflammation of serous sacs, proteinuria, seizures,
anemia, leukopenia, thrombocytopenia
Rheumatoid Arthritis - correct answer - E. Primarily women 30-50, systemic
autoimmune disease
Progressive, irreversible leads to deformity and disability
Tx includes PT, NSAIDS, corticosteroids
C.M. Joint inflammation, pain, destruction of synovial membrane,
widespread symmetrical joint swelling, erythema joints warm to touch, loss
of function, morning stiffness- improves with movement, weight loss,
weakness, anorexia
-Osis or -philia - correct answer - Elevated count of blood cells
-penia - correct answer - Low count of blood cells
Leukocytosis - correct answer - Increase in number of total WBC
Leukopenia - correct answer - Decrease in number of total WBC