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1. Which cell component is capable of cellular autodigestion when it is re-
leased during cell injury?
Ribosomes
Golgi complex
Smooth endoplastic reticulum
Lysosomes: Lysosomes
2. Which mode of chemical signaling uses blood to transport communication
to cells some distance away?
Paracrine
Autocrine
Neurotransmitter
Hormonal: Hormonal
3. The loss of the adenosine triphosphate (ATP) during ischemia causes cells
to:
Swell because of the influx of sodium chloride (NaCl)
Swell because of the influx of nitric oxide (NO): Swell because of the influx of
sodium chloride (NaCl)
4. During cell injury caused by hypoxia, an increase in the osmotic pressure
occurs within the cell because:
Plasma proteins enter the cell
The adenosine triphoshatase (ATPase_-driven pump is stronger during hyp-
poxia
Sodium chloride enters the cell
An influx of glucose occurs through the injured cell membranes: Sodium
chloride enters the cell
5. A patient's blood gases reveal the following findings: pH 7.3; bicarbonate
(HCO3) 27 mEq/L; carbon dioxide (CO2) 58 MM hG
What is the interpretation of these gases?
Respiratory alkalosis
Metabolic acidosis
Respiratory acidosis
Metabolic alkalosis: Respiratory acidosis
6. Vomiting-induced metabolic alkalosis, resulting in the loss of chloride,
causes:
Retained sodium to bind with the chloride
Hydrogen to move into the cell and exchange with potassium to maintain
cation balance
Retention of bicarbonate to maintain the anion balance
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, Quiz 1- NURS 530 PATHO/PHYS
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Hypoventilation to compensate for the metabolic alkalosis: Retention of bicar-
bonate to maintain the anion balance
7. Inserting bone marrow cells into an individual who produces abnormal
erythrocytes is an example of what type of therapy?
Somatic cell
Germ cell
Genetic engineering
Recombinant DNA: Somatic cell
8. An individual's genetic makeup is referred to as his or her:
Phenotype
Genotype
Heterozygous locus
Homozygous locus: Genotype
9. The ratio of the disease among the exposed population to the disease rate
in an unexposed population is referred to as what type of risk?
Attributable
Contingency
Casual
Relative: Relative
10. Studies have identified several genes that play a role in the prevention of
obesity by affecting what?
Regulation of appetite
Metabolizing of fat
Absorption of fat
Altering the sense of satiety: Regulation of appetite
11. Which term refers to the silenced gene of a gene pair?
Activated
Mutated
Imprinted: Imprinted
12. A malfunction in DNA methylation can lead to:
Hypothyroidism
Blindness
Cancer
Diabetes Mellitus: Cancer
13. Osmosis: movement of water across a membrane
14. Hydrostatic pressure: pressure that is exerted by a fluid (at equilibrium) at a
given point within the fluid, due to the force of gravity
15. Oncotic pressure: induced by proteins (i.e., albumin), causes a pull of fluid back
into the capillary
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