Chapter 01: Cellular Biology
U U U
Huether: Understanding Pathophysiology, 7th
U U U
Edition
U
MULTIPLE
UCHOICE
1. A Ustudent Uis Uobserving Ua Ucell Uunder Uthe Umicroscope. UIt Uis
Uobserved Uto Uhave Usupercoiled UDNAwith Uhistones. UWhich Uof
UtheUfollowing Uwould Ualso Ube Uobserved Uby Uthe Ustudent?
a. A Usingle Ucircular Uchromosome
b. A Unucleus
c. Free-floating Unuclear Umaterial
d. No Uorganelles
ANS:
UB
The Ucell Udescribed Uis Ua Ueukaryotic Ucell, Uso Uit Uhas Uhistones
Uand Ua Usupercoiled U DNA Uwithin U itsnucleus; Uthus, U the
Unucleus Ushould Ube Uobserved. UA Usingle Ucircular Uchromosome
2. UAcalled UaUU
Unurse isprokaryote contains
Uinstructing
U Ufree-floating
Uthe Ustaff Unuclear
Uabout Ucellular Umaterial
Ufunctions. UWhich Ucellular Ufunction Uis Uthe
Ubut
U Uhas
nurse Uno Uorganelles.
Udescribing Uwhen Uan Uisolated Ucell Uabsorbs Uoxygen Uand Uuses Uit Uto Utransform Unutrients
Uto Uenergy?
a. Metabolic Uabsorption
b. Communication
c. Secretion
d. Respiration
ANS: U D
The Ucell’s Uability Uto Uabsorb Uoxygen Uis Ureferred Uto Uas Urespiration Uwhile Uits Ucommunication
involves Umaintenance Uof Ua UsteadNy Udynamic Ustate, Umetabolic Uabsorption Uprovides
UabilityU
Unutrition, U and Usecretion Uallows Ufor Uthe Usynthesizing Uof Unew Usubstances.
3. A Ueukaryotic Ucell Uis Uundergoing UDNA Ureplication. UIn Uwhich Uregion Uof Uthe Ucell Uwould
U most UofUthe Ugenetic Uinformation Ube Ucontained?
a. Mitochondria
b. Ribosome
c. Nucleolus
d. Nucleus Ucytoplasm
ANS: U C
The Uregion Uof Uthe Ucell Uthat Ucontains Ugenetic Umaterial, Uincluding Ua Ularge Uamount Uof
UribonucleicU acid, Umost Uof Uthe UDNA, Uand UDNA-binding Uproteins, Uis Uthe Unucleolus, Uwhich Uis
Ulocated UwithinU the Ucell’s Unucleus. UMitochondria Uis Uassociated Uwith Ucellular Urespiration
Uwhile Uribosomes Uare Uinvolved Uwith Uprotein Umanufacturing. UCytoplasm Uis Ua Ufluid Ufilling
Uthat Uis Ua Ucomponent Uof UtheU cell.
4. Which Uof Uthe Ufollowing Ucan Uremove Uproteins Uattached Uto Uthe Ucell’s Ubilayer Uby
dissolving UtheUlayer Uitself?
U
a. Peripheral Umembrane Uproteins
b. Integral Umembrane Uproteins
c. Glycoproteins
d. Cell Uadhesion Umolecules
,TEST UBANK UFOR UUNDERSTANDING UPATHOPHYSIOLOGY U7TH UEDITION UBY UHUETHER
ANS: U B
Proteins Udirectly Uattached Uto Uthe Umembrane Ubilayer Ucan Ube Uremoved Uby Uthe Uaction Uof
Uintegral Umembrane Uproteins Uthat Udissolve Uthe Ubilayer. UPeripheral Umembrane Uproteins Ureside
Uat Uthe Usurface Uwhile Ucell Uadhesion Umolecules Uare Uon Uthe Uoutside Uof Uthe Umembrane.
UGlycoprotein Umarks Ucells Uand Udoes Unot U float.
5. Which Uof Uthe Ufollowing Ucan Ubind Uto Uplasma Umembrane Ureceptors?
a. Oxygen
b. Ribosomes
c. Amphipathic Ulipids
d. Ligands
ANS: U D
Ligands Uare Uthe Uonly Uspecific Umolecules Uthat Ucan Ubind Uwith Ureceptors Uon Uthe Ucell Umembrane.
6. A Unurse Uis Ureviewing Ua Ureport Ufrom Ua Upatient Uwith Umetastatic Ucancer. UWhat Ualternation
in UtheUextracellular Umatrix Uwould Usupport Uthe Udiagnosis Uof Umetastatic Ucancer?
U
a. Decreased Ufibronectin
b. Increased Ucollagen
c. Decreased Uelastin
d. Increased Uglycoproteins
ANS: U A
Only Ua Ureduced Uamount Uof Ufibronectin Uis Ufound Uin Usome Utypes Uof Ucancerous Ucells,
UallowingU them Uto Utravel Uor Umetastasize.
7. Which Uform Uof Ucell Ucommunication Uis Uused Uto Urelate Uto Uother Ucells Uin Udirect Uphysical
contact?
U
a. Cell Ujunction N
b. Gap Ujunction
c. Desmosome
d. Tight Ujunction
ANS: U A
Cell Ujunctions Uhold Ucells Utogether Uand Upermit Umolecules Uto Upass Ufrom Ucell Uto Ucell. UGap
Ujunctions U
allow Ufor Ucellular Ucommunication Ubetween Ucells. UNeither Udesmosomes Unor Utight
Ujunctions Uare Uassociated Uwith Ucellular Ucommunication.
8. Pancreatic Ubeta Ucells Usecrete Uinsulin, Uwhich Uinhibits Usecretion Uof Uglucagon Ufrom
neighboringUalpha Ucells. UThis Uaction Uis Uan Uexample Uof Uwhich Uof Uthe Ufollowing Usignaling
U
Utypes?
a. Paracrine
b. Autocrine
c. Neurohormonal
d. Hormonal
ANS: U A
Paracrine Usignaling Uinvolves Uthe Urelease Uof Ulocal Uchemical Umediators Uthat Uare Uquickly Utaken
Uup,Udestroyed, Uor Uimmobilized, Uas Uin Uthe Ucase Uof Uinsulin Uand Uthe Uinhibition Uof Uthe Usecretion
Uof Uglucagon. UNone Uof Uthe Uother Uoptions Uinvolve Usignaling Uthat Uis Uassociated Uwith Ua Ulocal
Uchemical Umediator Ulike Uinsulin.
9. In Ucellular Umetabolism, Ueach Uenzyme Uhas Ua Uhigh Uaffinity Ufor Ua:
a. solute.
, TEST UBANK UFOR UUNDERSTANDING UPATHOPHYSIOLOGY U7TH UEDITION UBY UHUETHER
b. substrate.
c. receptor.
d. ribosome.
ANS: U B
Each Uenzyme Uhas Ua Uhigh Uaffinity Ufor Ua Usubstrate, Ua Uspecific Usubstance Uconverted Uto Ua
Uproduct UofU
the Ureaction. UCellular Umetabolism Uis Unot Udependent Uon Uan Uattraction Ubetween
Uan Uenzyme Uand Uany Uof Uthe Uremaining Uoptions.
10. An Uathlete Uruns Ua Umarathon, Uafter Uwhich Uhis Umuscles Ufeel Ufatigued Uand Uunable Uto Ucontract.
UThe Uathlete Uasks Uthe Unurse Uwhy Uthis Uhappened. UThe Unurse’s Uresponse Uis Ubased Uon Uthe
Uknowledge UthatU the Uproblem Uis Uresult Uof Ua Udeficiency Uof:
a. GTP.
b. AMP.
c. ATP.
d. GMP.
ANS: U C
When UATP Uis Udeficient, Uimpaired Umuscle Ucontraction Uresults. UNone Uof Uthe Uother Uoptions
UareU
involved Uin Umuscle Ucontraction.
11. Which Uphase Uof Ucatabolism Uproduces Uthe Umost UATP?
a. Digestion
b. Glycolysis
c. Oxidation
d. Citric Uacid Ucycle
ANS: U D N
While Usome UATP Uis Uproduced Uduring Uthe Uoxidation Uand Uglycolysis Uphases, U most Uof Uthe UATP
Uis
generated Uduring Uthe Ucitric Uacid Ucycle. UDigestion Udoes Unot Uproduce Uany UATP.
12. A Unurse Uis Uteaching Uthe Ustaff Uabout Uthe Uphases Uof Ucellular Ucatabolism. UWhich Uphases
Ushould UtheUnurse Uinclude?
a. Digestion, Uglycolysis, Uoxidation, Uand Uthe Ucitric Uacid Ucycle
b. Diffusion, Uosmosis, Uand Umediated Utransport
c. S Uphase, UG Uphase, Uand UM Uphase
d. Metabolic Uabsorption, Urespiration, Uand Uexcretion
ANS: U A
Only Udigestion, Uglycolysis, Uoxidation, Uand Uthe Ucitric Uacid Ucycle Uare Uthe Uphases Uof
UcellularU
catabolism.
13. A Urunner Uhas Udepleted Uall Uthe Uoxygen Uavailable Ufor Umuscle Uenergy. UWhich Uof Uthe
Ufollowing UwillUfacilitate Uhis Ucontinued Umuscle Uperformance?
a. Electron-transport Uchain
b. Aerobic Uglycolysis
c. Anaerobic Uglycolysis
d. Oxidative Uphosphorylation
ANS: U C
, TEST UBANK UFOR UUNDERSTANDING UPATHOPHYSIOLOGY U7TH UEDITION UBY UHUETHER
When Uno Uoxygen Uis Uavailable, Uanaerobic Uglycolysis Uoccurs. UThe Uelectron-transport Uchain Uis
UpartU
of Uthe Ucitric Uacid Ucycle. UAerobic Uglycolysis Uinvolves Uthe Upresence Uof Uoxygen.
UOxidative Uphosphorylation Uis Uthe Umechanism Uby Uwhich Uthe Uenergy Uproduced Ufrom
Ucarbohydrates, Ufats, Uand Uproteins Uis Utransferred Uto UATP. U It Uis Unot Upart Uof Umuscle
Uperformance.
14. A Ufaculty Umember Uasks Ua Ustudent Uto Uidentify Uthe Uappropriate Uterm Ufor Uthe Umovement Uof Ua
UsoluteUfrom Uan Uarea Uof Ugreater Uto Ulesser Uconcentration. UWhich Uanswer Uindicates Uthe
Unursing Ustudent Uunderstood Uthe Uteaching?
a. Osmosis
b. Diffusion
c. Hydrostatic Upressure
d. Active Utransport
ANS: U B
Diffusion Uis Uthe Umovement Uof Ua Usolute Umolecule Ufrom Uan Uarea Uof Ugreater Usolute
Uconcentration UtoU an Uarea Uof Ulesser Usolute Uconcentration Uthrough Ua Upermeable Umembrane.
UOsmosis Uis Uthe Umovement Uof Uwater Uacross Ua Usemipermeable Umembrane Ufrom Ua Uregion Uof
Uhigher Uwater Uconcentration Uto Uone Uof Ulower U concentration. U Hydrostatic Upressure Uis Uthe
Uforce Uof Ufluid Uagainst Ua Ucell Umembrane. U In Uactive Utransport, Umolecules U move Uup Ua
Uconcentration Ugradient.
15. Which Udescription Uaccurately Udescribes Uelectrolytes?
a. Small Ulipid-soluble Umolecules
b. Large Uprotein Umolecules
c. Micronutrients Uused Uto Uproduce UATP
d. Electrically Ucharged Umolecules
ANS: U D
Electrolytes Uare Uelectrically UchaNrged Umolecules. UThey Uare Unot Ulipid Usoluble, Uthey Uare Unot Umade
up Uof Uprotein, Uand Uthey Udo Unot Uplay Ua Urole Uin UATP Uproduction.
16. A Unurse Uis Ureading Ua Uchart Uand Usees Uthe Uterm Uoncotic Upressure. UThe Unurse Urecalls Uthat
UoncoticUpressure U(colloid Uosmotic Upressure) Uis Udetermined U by:
a. the Uconcentration Uof Usodium.
b. plasma Uproteins.
c. hydrostatic Upressure.
d. the Uavailability Uof Umembrane Utransporter Uproteins.
ANS: U B
Oncotic Upressure Uis Udetermined Uby Uthe Ueffect Uof Ucolloids Uor Uplasma Uproteins. UThe
Uconcentration U
of Usodium Uplays Ua Urole Uin Utonicity. UHydrostatic Upressure Uis Uthe Uforce Uwithin Ua
Uvessel. UMembrane U transporter Uproteins Uare Uinvolved Uin Uactive Utransport Uwithin Ua
Uconcentration Ugradient.
17. A Upatient Uhas Ua Ubody Ufluid Uof U300 UmOsm/kg. UThis Ulab Uresult Uis Umeasuring:
a. osmolality.
b. osmolarity.
c. osmotic Upressure.
d. oncotic Upressure.
ANS: U A