A biomarker with a high specificity:
- ANSWERS-accurately detects the absence of disease and has few false-positives
A biomarker with high sensitivity:
- ANSWERS-accurately identifies the presence of disease and hos few false-negatives
A hapten is only antigenic when it is coupled with which of the following:
- ANSWERS-Proteins
A mojor action of angiotensin II is:
- ANSWERS-increased vasocontriction
A patient experiences a mild allergic reaction to a transfusion, including urticaria, erythema (skin redness),
and itching. What is the most likely source of the allergen?
- ANSWERS-Plasma proteins
Mild allergic reactions result from a patient's hypersensitivity to soluble allergens in the plasma of the
donor unit. The blood recipient forms antibodies to these allergens that are bound to IgE on mast cells and
cause the release of histamines. Allergen substances may be drugs or food consumed by the blood donor.
Adiponectin:
- ANSWERS-Is aprotective cytokine. This cytokine is anti-inflammatory and increases insulin sensitivity.
Adiponectin is usually decreased in obesity
Alder-Reilly inclusions:
- ANSWERS-Mucopolysaccarids
Alpha thalassemia major:
- ANSWERS-
Alpha thalassemia Major:
- ANSWERS-AKA as Hydrops Fetalis, is exhibited when all four alpha chain gene loci are deleted or non-
,functional. The alpha chain is crucial to the formation of hemoglobin variants that can conduct normal
oxygen transport and gas exchange. The genetic code --/-- is incompatible with life.
Amorphous phosphate crystals are found in:
- ANSWERS-Amorphous phosphate, triple phosphate (ammonium magnesium phosphate), calcium
phosphate, and ammonium urate crystals are frequently found in alkaline urine specimens
Amorphous urates is found in:
- ANSWERS-Acidic pH urine
ANA
- ANSWERS-See 2 quiz #27
Approximately what percent of the overall population is Rh negative:
- ANSWERS-15%
Average life span of platelets (in the body):
- ANSWERS-9.5 days
B lymphocytes and T lymphocytes are derived from:
- ANSWERS-Hematopoietic stem cells
Beta thalassemia major
- ANSWERS-
Beta thalassemia minor:
- ANSWERS-
Blood Gas Reference Ranges:
- ANSWERS-pH: 7.35-7.45
pCO2: 35-45 mm Hg
HCO3: 22-26 mM/L
pO2: 85-105 mmHg
, Blood reaction grades; 1+, 2+, 3+ and 4+
- ANSWERS-1+: reaction has numerous small clumps and cloudy red supernatant
2+: has many medium-sized clumps and clear supernatant
3+: has several large clumps and clear supernatant
4+: has one solid clump, no free cells, and clear supernatant
Causes of Vitamin B12 deficiency:
- ANSWERS-Pericious anemia in relapse, Patients on chronic hemodialysis and hodgkin disease
CD34
- ANSWERS-Best associated with stem cells, present on undifferentiated pluipotential hemopoietic stem
cell. CD34 is a cell surface glycoprotein and functions as a cell-cell adhesion factor
CD5 antigen is normally found on which of the following lymphocyte populations?
- ANSWERS-Mature T cells
Christmas Disease:
- ANSWERS-Deficiency in Factor IX
Chylomicrons are primarily composed of:
- ANSWERS-Triglycerides
Contact dermatitis is mediated by:
- ANSWERS-T lymphocytes
Coulometry:
- ANSWERS-An automated method for measuring chloride which generates silver ions in the reaction
Crigler-Najjar syndrome:
- ANSWERS-Associated with increased levelss of bilirubin in the blood as teh disorder affect the etabolism
of bilirubin