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1. What are some signs of Thyroid medication toxicity? - ANSWER ✔
irritability, insomnia, tachycardia, arrhythmias, elevated blood pressure,
anxiety, weight loss, all similar signs of hyperthyroidism.
2. Which antithyroid drug is used in pregnancy - ANSWER ✔ Propylthiouracil
3. Which antithyroid drug has a black box warning for liver injury - ANSWER
✔ Propylthiouracil
4. Advantages of Methimazole over Propylthiouracil - ANSWER ✔
Methimazole is more potent, less toxic, not protein bound, and does not
carry black box warning about liver damage
5. What adverse reactions can antithyroid medications cause - ANSWER ✔
Allergic reactions such as rash, and urticaria; Nausea and vomiting during
initiation of therapy; agranulocytosis and thrombocytopenia;
Hypothyroidism (with long term therapy); reoccurrence of hyperthyroidism
after stopping treatment.
6. Which antidiabetics cause hypoglycemia - ANSWER ✔ Sulfonylureas,
meglitinides, amylin agonists can all cause hypoglycemia.
Thiazolidinediones, Alpha Glucose inhibitors, and GLP-1 analogs can
potentiate hypoglycemia when given with other antidiabetics.
,7. Which anti-diabetics are nephroprotective - ANSWER ✔ DPP-4 (-gliptins)
because in patients without severe renal impairment, the typical progression
of microalbuminuria to proteinuria in DM appears to be reversed after 2
years on saxagliptin use
8. Which anti-diabetics require dosage adjustments for renal impairment. -
ANSWER ✔ DPP-4 (gliptins) and SGLT-2 inhibitors require dosage
adjustments while
Metformin and Sulfonylureas are contraindicated in patients with renal
failure.
9. Which anti-diabetic medications are contraindicated in Liver disease -
ANSWER ✔ Metformin, Sulfonylureas, and Thiazolidinediones
10.What oral hypoglycemic is preferred in pregnancy - ANSWER ✔ Metformin
11.Which oral hypoglycemic drug has a black box warning for CHF -
ANSWER ✔ Thiazolidinediones (zones)
12.Special consideration when treating DM with an alpha glucosidase inhibitor
and another hypoglycemic drug - ANSWER ✔ If hypoglycemia occurs you
cannot treat with oral complex sugars; can still treat with glucose.
13.Which anti-diabetic medication can be used for both type 1 and type 2
diabetes. - ANSWER ✔ Amylin Analogs (Pramlintide)
14.Which anti-diabetics are contraindicated in diabetic gastroparesis? -
ANSWER ✔ Amylin analogs (pramlintide) and DPP-4 inhibitors (gliptins)
15.Which anti-diabetic drug causes mycotic infections? - ANSWER ✔ SGLT-2
inhibitors (flozins)
16.Which anti-diabetics carry a black box warning for Thyroid tumors? -
ANSWER ✔ GLP-1 analogs (tides)
17.How does CSF protect the CNS? - ANSWER ✔ Provides cushion for brain
structures
Reduces pressure on brain structures
, Removes harmful substances
Transports hormones to remote sites in the brain
18.Where is CSF produced? - ANSWER ✔ choroid plexus in ventricles
19.the pH regulation of CSF - ANSWER ✔ CSF high in Na and low in K
delicate
20.substances that move across the blood brain barrier easily - ANSWER ✔
water, carbon dioxide, and oxygen
21.lipid soluble molecules that cross the lipid layer easily - ANSWER ✔
heroine, alcohol, nicotine
22.substances that have a slow and controlled movement across the blood brain
barrier - ANSWER ✔ large molecules (proteins and peptides)
water-soluable molecules
23.what does the blood brain barrier protect against in new borns - ANSWER
✔ bilirubin build up
24.cranial nerves - ANSWER ✔ location
25.cranial nerves pnemonic - ANSWER ✔
26.where does the SNS leave the cns - ANSWER ✔ thoracolumbar level
27.What does the sympathetic nervous system do? - ANSWER ✔ Fight or
flight response
- Accelerates the heart rate, constrict blood vessels, and raises blood
pressure
28.Where does the parasympathetic nervous system originate? - ANSWER ✔
cranial and sacral level
29.What does the parasympathetic nervous system do? - ANSWER ✔ rest and
digest
, 30.two types of catcholamines - ANSWER ✔ alpha 1- blood vessels contrict
(excitatory)
beta 1- increase HR and contrict force
Alpha 2- central control of bP ( inhibitory)
beta 2- opens airways
31.What does acetylcholine do? - ANSWER ✔ it is a neurotransmitter. It
simulates or actives the next nerve cell as impulses pass down the a nerve,
responsible for control of vital functions, essential for homeostasis
32.cholinergic receptors - ANSWER ✔ nicotinic and muscarinic
33.the sensory unit consists of 3 primary levels - ANSWER ✔ sensory units
containing the sensory receptor, the ascending pathways, and the central
processing centers in the thalamus and cerebral cortex
34.what does a sensory unit consist of - ANSWER ✔ a single dorsal root
ganglion neuron, its receptors, and its central axon that terminates in the
dorsal horn of the spinal cord or medulla.
35.first order neurons - ANSWER ✔ · transmit information from sensory
receptors to dorsal horn neurons
36.second order neurons - ANSWER ✔ · communicate with various reflex
circuits and transmit information to the thalamus
37.third order neurons - ANSWER ✔ forward the information from the
thalamus to the sensory cortex
38.What is a dermatome? - ANSWER ✔ specific segment of skin supplied by a
single spinal nerve, dorsal root ganglia
39.white matter - ANSWER ✔ act like highways- transfer info
40.gray matter - ANSWER ✔ focuses on interpretation
41.how can chicken pox also cause shingles - ANSWER ✔ dorsal root ganglia