HBIO320 FINAL EXAM (NEW MATERIAL) QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS GRADED A++

HBIO320 FINAL EXAM (NEW MATERIAL) QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS GRADED A++ animal hindlimb immobilization/unloading models ______ and ______, while cordotomy/ denervation models __________ bed rest, casting, spinal cord injury lengthened/ shortened (?) immobilized muscle partially spares loss of muscle mass due to less loss of sarcomeres in series lengthened T/F: mass is a good predictor of Po false _____ is a good predictor of Po CSA soleus muscle in rat cordotomy model had an increase/ decrease (?) in type ____ fiber density increase, II T/F: in rat cordotomy model, EDL was relatively unchanged true EDL remained unchanged due to _________ preservation of lower motor units disuse atrophy is due to increased degradation/ decreased synthesis (?) increased degradation after denervation, red and white muscle ______ atrophy T/F: there are changes in fiber type after denervation true whitening of red muscle nAChR become ____________ after denervation diffusely spread T/F: NCAM helps guide redevelopment of NMJ True Cross-reinervation experiments showed that nerves did/ did not (?) reinervate appropriate fiber type did not go to nearest receptive fiber regardless of type ______ and ______ are transcription factors responsible for atrophy gene activation MuRF and MAFbx If FOXO is phosphorylated, can it transverse into the nucleus? NO ______ binding to activin 2 receptor leads to _____ activation by blocking AKT-dependent phosphorylation via _______ myostatin, FOXO, SMAD 2/3 when hypertrophy pathways are activated, AKT phos/dephos (?) FOXO phos ubiquination intracellular protein degradation ____, ____, and ____ somewhat recovers after neurovascular supply cut and then the muscle is put back in same location ___ does not recover TPT, 1/2 RT, CSA Po for moving muscle for which it is not designed, it should be transplanted or transposed? transplanted want the muscle to establish its own blood supply age of donor or age of recipient is more important in transplant? age of recipient DOMS is caused by _____ contractions eccentric