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Reversible cell injury
Type of cell injury caused by hydropic swelling( excess water in cell)
Metaplasia
When cells change from one cell type to another
necrosis
Unplanned cell death
apoptosis
Planned cell death
bioavailability
The amount of drug that is available to the body to produce a therapeutic effect
Pharmacodynamics
The mechanism whereby drugs exert their effect on the body.
Competitive enzyme inhibition
Action where medicine is competing with the natural substrate for access to the binding
site of the enzyme.
Agonist
When a drug acts on a receptor to produce a response
, antagonist
When a drug blocks a receptor
affinity
Extent of the binding for a drug to a receptor
specificity
Degree of selectivity of a drug to receptors
efficacy
Ability of a drug to produce an effect at a receptor
potency
The relative amount of drug that has to be present to produce desired clinical effect.
inflammation
Non- specific, first line body defence response to cell injury
vascular and cellular
What are the two phases of inflammation
Vascular phase
The phase of inflammation where mediators induce a vasodilatory response in the
affected tissue
diapedesis
White blood cells are drawn to the site of tissue injury by chemical mediators
exudate
What is the fluid that during the vascular phase, fluid moves out of the blood vessels
and accumulates in the tissues
Atherosclerosis