C HAPTER 21: D RUGS U SED TO T REAT
D YSLIPIDEMIAS
Willihnganz: Clayton’s Basic Pharmacology for Nurses, 19th Edition
MULTIPLE CHOICE
1. Which desired effect applies to antilipemic therapy?
a. Reduced LDLs and total cholesterol levels
b. Reduced HDLs and total cholesterol levels
c. Reduced LDLs and HDLs
d. Reduced HDLs and dietary cholesterol levels
ANS: A
LDLs account for 60% to 70% of total serum cholesterol and are a major
contributor to atherosclerosis. The therapeutic outcome of antilipemic
therapy is to low er the LDL and total cholesterol levels and raise the HDL
and HDL/ LDL ratio. HDLs are not reduced in treating hyperlipidemia.
DIF: Cognitive Level: Comprehension REF: p. 340 OBJ: 3 |
4
NAT: NCLEXClient Needs Category: Health Promotion and
Maintenance
TOP: Nursing Process Step: Assessment CON: Clinical Judgment
2. Which s ymptoms, in addition to controlling hyperlipidemia, are bile acid –
binding resins prescribed to treat?
a. Constipation secondary to excess fecal bile acids
b. Constipation related to pseudomemb ranous colitis
, c. Pruritus secondary to biliary stasis
d. Jaundice related to cholelithiasis
ANS: C
Bile acid–binding resins may be used to treat pruritus as a result of partial
biliary stasis. Excess fecal bile acids produce diarrhea. Pseudomembranous
colitis produces diarrhea. Bile acid –binding resins are not used to treat
jaundice.
DIF: Cognitive Level: Comprehension REF: p. 345 OBJ: 4
NAT: NCLEXClient Needs Category: Physiological Integrit y
TOP: Nursing Process Step: Implementation
CON: Clinical Judg ment
3. Which antilipemic agent is most potent?
a. Niacin
b. HMG-CoA reductase inhibitor
c. Bile acid–binding resin
d. Fibric acid
ANS: B
HMG-CoA reductase inhibitors are the most potent antilipemic agents
available. Niacin, bile acid –binding resins, and fibric a cid are not as potent
as HMG-CoA reductase inhibitors.
DIF: Cognitive Level: Knowledge REF: p. 342 OBJ: 3 | 4
NAT: NCLEXClient Needs Category: Physiological Integrit y
TOP: Nursing Process Step: Implementation
CON: Clinical Judgment
D YSLIPIDEMIAS
Willihnganz: Clayton’s Basic Pharmacology for Nurses, 19th Edition
MULTIPLE CHOICE
1. Which desired effect applies to antilipemic therapy?
a. Reduced LDLs and total cholesterol levels
b. Reduced HDLs and total cholesterol levels
c. Reduced LDLs and HDLs
d. Reduced HDLs and dietary cholesterol levels
ANS: A
LDLs account for 60% to 70% of total serum cholesterol and are a major
contributor to atherosclerosis. The therapeutic outcome of antilipemic
therapy is to low er the LDL and total cholesterol levels and raise the HDL
and HDL/ LDL ratio. HDLs are not reduced in treating hyperlipidemia.
DIF: Cognitive Level: Comprehension REF: p. 340 OBJ: 3 |
4
NAT: NCLEXClient Needs Category: Health Promotion and
Maintenance
TOP: Nursing Process Step: Assessment CON: Clinical Judgment
2. Which s ymptoms, in addition to controlling hyperlipidemia, are bile acid –
binding resins prescribed to treat?
a. Constipation secondary to excess fecal bile acids
b. Constipation related to pseudomemb ranous colitis
, c. Pruritus secondary to biliary stasis
d. Jaundice related to cholelithiasis
ANS: C
Bile acid–binding resins may be used to treat pruritus as a result of partial
biliary stasis. Excess fecal bile acids produce diarrhea. Pseudomembranous
colitis produces diarrhea. Bile acid –binding resins are not used to treat
jaundice.
DIF: Cognitive Level: Comprehension REF: p. 345 OBJ: 4
NAT: NCLEXClient Needs Category: Physiological Integrit y
TOP: Nursing Process Step: Implementation
CON: Clinical Judg ment
3. Which antilipemic agent is most potent?
a. Niacin
b. HMG-CoA reductase inhibitor
c. Bile acid–binding resin
d. Fibric acid
ANS: B
HMG-CoA reductase inhibitors are the most potent antilipemic agents
available. Niacin, bile acid –binding resins, and fibric a cid are not as potent
as HMG-CoA reductase inhibitors.
DIF: Cognitive Level: Knowledge REF: p. 342 OBJ: 3 | 4
NAT: NCLEXClient Needs Category: Physiological Integrit y
TOP: Nursing Process Step: Implementation
CON: Clinical Judgment
