C HAPTER 22: D RUGS U SED TO T REAT
H YPERTENSION
Willihnganz: Clayton’s Basic Pharmacology for Nurse s, 19th Edition
MULTIPLE CHOICE
1. Which adverse effect is associated ACE inhibitors?
a. Constipation
b. Chronic cough
c. Hypokalemia
d. Nervousness
ANS: B
Chronic cough may develop in as many as one -third of patients receiving
ACE inhibitors. Constipation, hypokalemia, and nervousness are not adverse
effects of this medication.
DIF: Cognitive Level: Knowledge REF: p. 366 OBJ: 5
NAT: NCLEX Client Needs Category: Physiological Integrit y
TOP: Nursing Process Step: Implementation
CON: Clinical Judgment | Patient Education | Safet y
2. Which statement accuratel y describes the action ACE inhibitors?
a. They increase aldosterone secretion.
b. They inhibit vasoconstriction.
c. They lower heart rate.
d. They promote sodium retention.
, ANS: B
ACE inhibitors decrease vasoconstriction and aldosterone secretion. ACE
inhibitors do not increase aldosterone secretion, lower the heart rate, or
promote sodium retention.
DIF: Cognitive Level: Comprehension REF: p. 364 OBJ: 5
NAT: NCLEX Client Needs Category: Physiological Integrit y
TOP: Nursing Process Step: Implementation
CON: Clinical Judgment | Patient Education
3. Which common adverse effect of an angiotensin II receptor antagonist will
the nurse expect to assess in a patient?
a. Bradycardia
b. Headache
c. Hypokalemia
d. Insomnia
ANS: B
Headache is a common adverse effect of angiotensin II receptor antagonists.
Bradycardia, hypokalemia, and insomnia are not common adverse effects of
angiotensin II re ceptor antagonists.
DIF: Cognitive Level: Comprehension REF: p. 369 OBJ: 5
NAT: NCLEX Client Needs Category: Physiological Integrit y
TOP: Nursing Process Step: Assessment CON: Clinical Judgment
4. Which medication lowers blood pressure by directl y inhibi ting renin?
a. Aliskiren (Tekturna)
b. Eplerenone (Inspra)
, c. Diltiazem (Cardizem)
d. Reserpine
ANS: A
Aliskiren is a renin angiotensin antagonist. Eplerenone blocks the action of
aldosterone. Diltiazem is a calcium channel blocker. Reserpine depletes
catecholamines.
DIF: Cognitive Level: Knowledge REF: p. 369 OBJ: 5
NAT: NCLEX Client Needs Category: Physiological Integrit y
TOP: Nursing Process Step: Implementation CON: Clinical
Judgment
5. Which response will the nurse provide when a patient asks the nurse ho w
amlodipine (Norvasc) works to reduce the blood pressure?
a. “It causes blood vessel dilation. ”
b. “It helps you get rid of fluid. ”
c. “It helps your heart beat stronger. ”
d. “It slows your heart rate. ”
ANS: A
Dihydropyridines (amlodipine) are calcium channel bloc king medications that
work by inhibiting the vasoconstricting effects of calcium to cause
vasodilation. Amlodipine does not have a diuretic effect or cause the heart to
contract more forcefull y. Calcium channel blockers do slow the heart rate;
however, the dihydropyridines (amlodipine) have peripheral vasodilating
effects.
DIF: Cognitive Level: Comprehension REF: p. 372 OBJ: 5
NAT: NCLEX Client Needs Category: Physiological Integrit y
TOP: Nursing Process Step: Implementation
H YPERTENSION
Willihnganz: Clayton’s Basic Pharmacology for Nurse s, 19th Edition
MULTIPLE CHOICE
1. Which adverse effect is associated ACE inhibitors?
a. Constipation
b. Chronic cough
c. Hypokalemia
d. Nervousness
ANS: B
Chronic cough may develop in as many as one -third of patients receiving
ACE inhibitors. Constipation, hypokalemia, and nervousness are not adverse
effects of this medication.
DIF: Cognitive Level: Knowledge REF: p. 366 OBJ: 5
NAT: NCLEX Client Needs Category: Physiological Integrit y
TOP: Nursing Process Step: Implementation
CON: Clinical Judgment | Patient Education | Safet y
2. Which statement accuratel y describes the action ACE inhibitors?
a. They increase aldosterone secretion.
b. They inhibit vasoconstriction.
c. They lower heart rate.
d. They promote sodium retention.
, ANS: B
ACE inhibitors decrease vasoconstriction and aldosterone secretion. ACE
inhibitors do not increase aldosterone secretion, lower the heart rate, or
promote sodium retention.
DIF: Cognitive Level: Comprehension REF: p. 364 OBJ: 5
NAT: NCLEX Client Needs Category: Physiological Integrit y
TOP: Nursing Process Step: Implementation
CON: Clinical Judgment | Patient Education
3. Which common adverse effect of an angiotensin II receptor antagonist will
the nurse expect to assess in a patient?
a. Bradycardia
b. Headache
c. Hypokalemia
d. Insomnia
ANS: B
Headache is a common adverse effect of angiotensin II receptor antagonists.
Bradycardia, hypokalemia, and insomnia are not common adverse effects of
angiotensin II re ceptor antagonists.
DIF: Cognitive Level: Comprehension REF: p. 369 OBJ: 5
NAT: NCLEX Client Needs Category: Physiological Integrit y
TOP: Nursing Process Step: Assessment CON: Clinical Judgment
4. Which medication lowers blood pressure by directl y inhibi ting renin?
a. Aliskiren (Tekturna)
b. Eplerenone (Inspra)
, c. Diltiazem (Cardizem)
d. Reserpine
ANS: A
Aliskiren is a renin angiotensin antagonist. Eplerenone blocks the action of
aldosterone. Diltiazem is a calcium channel blocker. Reserpine depletes
catecholamines.
DIF: Cognitive Level: Knowledge REF: p. 369 OBJ: 5
NAT: NCLEX Client Needs Category: Physiological Integrit y
TOP: Nursing Process Step: Implementation CON: Clinical
Judgment
5. Which response will the nurse provide when a patient asks the nurse ho w
amlodipine (Norvasc) works to reduce the blood pressure?
a. “It causes blood vessel dilation. ”
b. “It helps you get rid of fluid. ”
c. “It helps your heart beat stronger. ”
d. “It slows your heart rate. ”
ANS: A
Dihydropyridines (amlodipine) are calcium channel bloc king medications that
work by inhibiting the vasoconstricting effects of calcium to cause
vasodilation. Amlodipine does not have a diuretic effect or cause the heart to
contract more forcefull y. Calcium channel blockers do slow the heart rate;
however, the dihydropyridines (amlodipine) have peripheral vasodilating
effects.
DIF: Cognitive Level: Comprehension REF: p. 372 OBJ: 5
NAT: NCLEX Client Needs Category: Physiological Integrit y
TOP: Nursing Process Step: Implementation
