C HAPTER 16 - A NTIINFLAMMATORY ,
A NTIARTHRITIS , AND R ELATED A GENTS
Test Bank - Focus on Nursing Pharmacology (8th Edition by Karch)
1. A nurse has admitted a 10 -year-old child to the short -stay unit. The child
has complained of chronic headaches and his or her mother reports that he
or she gives him or her acetaminophen (Tylenol) at least tw ice a day. What
will the nurse evaluate?
a. Renal function
b. Hepatic function
c. Respiratory function
d. Cardiac function
Ans: B
Feedback:
The nurse should evaluate the patient’s hepatic function. Severe
hepatotoxicit y can occur from overuse of acetaminophen. Signif icant
interferences do not occur in the kidney, heart, or lung with acetaminophen.
2. The nurse is discussing ethnic differences in response to medication with
your nursing students. What group of people would the nurse tell the
students may have a decreased sensitivit y to pain-relieving effects of anti -
inflammatory drugs and should be educated concerning signs and
s ymptoms of gastrointestinal bleeding from use of these drugs?
a. African Americans
b. White Americans
c. Hispanics
d. Asians
, Ans: A
Feedback:
African Americans have a documented decreased sensitivit y to pain -relieving
effects of many antiinflammatory drugs. They also have an increased risk of
developing GI adverse effects to these drugs. In general, White Americans,
Hispanics, and Asians are at lower risk f or these problems.
3. A patient, newl y diagnosed with ulcerative colitis, has been admitted to the
short-stay unit. What salicylates does the nurse anticipate will be ordered
for this patient?
a. Balsalazide (Colazal)
b. Sodium thiosalicylate (generic)
c. Choline magnesium trisalicylate (Tricosal)
d. Salsalate (Argesic)
Ans: A
Feedback:
Balsalazide is delivered intact to the colon, where it delivers a local anti -
inflammatory effect that is most effective for patients with ulcerative colitis.
Choline salicylate and salsa late are used to treat pain, fever, and
inflammation. Sodium thiosalicylate is used mainl y for episodes of acute
gout, for muscular pain, and to treat rheumatic fever.
4. The nurse is caring for a 66 -pound child with orders for choline
magnesium trisalicyl at e (Tricosal). The orders read 50 mg/kg/d PO in two
divided doses. How many milligram will the patient receive per dose?
a. 250 mg
b. 500 mg
c. 750 mg
, d. 1,000 mg
Ans: C
Feedback:
First, the nurse must determine the child’s weight in kilogram. One kg is
equal to 2.2 pounds. Divide 2.2 into 66 to equal 30 kg. Multiply 50 mg times
30 kg to equal 1,500 mg. Divide 1,500 by 2 for the divided doses, which will
equal 750 mg per dose.
5. A nurse is caring for a patient with severe rheumatoid arthritis who takes
anti-inflammatory agents on a regular basis. What medication should the
nurse question if ordered by the physician to be taken in addition to the
anti-inflammatory agent?
a. Oral antidiabetic agent
b. Calcium channel blocker
c. Beta-blocker
d. Antibiotic
Ans: C
Feedback:
Nonsteroidal anti-inflammatory drugs have the potential to decrease
antihypertensive effects from beta blockers if these drugs are taken at the
same time. Patients who receive these combinations should be monitored
closel y and appropriate dosage adjustments made if ne eded. Drug interactions
do not usuall y occur with oral antidiabetic agents, calcium channel blocking
medications, or antibiotics.
6. A nurse is assessing a patient who has been taking nonsteroidal anti -
inflammatory drugs (NSAID). What statement by the patien t indicates to
, the nurse that the patient has a good understanding of the use of this
therapy?
a. I drink a glass of wine just about every night.
b. I asked m y doctor to check for blood in my stool regularl y.
c. I do not like to swallow tablets so I crush them.
d. I drink as little water as possible when I take m y medication.
Ans: B
Feedback:
Taking certain anti -inflammatory drugs can irritate the gastric mucosa and
increase the risk of bleeding; therefore, by asking his or her doctor to check
his or her stool for ble eding, the nurse knows that the patient is aware of this.
Alcohol and crushing the tablets can interfere with anti -inflammatory
metabolism. A full glass of water should be taken with this medication to
increase absorption.
7. A salicylate has been prescribed for a 15-year-old patient who has been
diagnosed with arthritis. The mother is concerned about giving her child a
salicylate. What salicylates could the nurse tell this mother are
recommended for use in children?
a. Salsalate (Argesic)
b. Olsalazine (Dipentum)
c. Sodium thiosalicylate (generic)
d. Choline magnesium trisalicylate (Tricosal)
Ans: D
Feedback:
Aspirin and choline magnesium trisalicyl ate are the onl y salicylates
recommended for use in children. They should not be used when any risk of
Reye’s syndrome exi sts. Salsalate (Argesic), olsalazine (Dipentum), and
A NTIARTHRITIS , AND R ELATED A GENTS
Test Bank - Focus on Nursing Pharmacology (8th Edition by Karch)
1. A nurse has admitted a 10 -year-old child to the short -stay unit. The child
has complained of chronic headaches and his or her mother reports that he
or she gives him or her acetaminophen (Tylenol) at least tw ice a day. What
will the nurse evaluate?
a. Renal function
b. Hepatic function
c. Respiratory function
d. Cardiac function
Ans: B
Feedback:
The nurse should evaluate the patient’s hepatic function. Severe
hepatotoxicit y can occur from overuse of acetaminophen. Signif icant
interferences do not occur in the kidney, heart, or lung with acetaminophen.
2. The nurse is discussing ethnic differences in response to medication with
your nursing students. What group of people would the nurse tell the
students may have a decreased sensitivit y to pain-relieving effects of anti -
inflammatory drugs and should be educated concerning signs and
s ymptoms of gastrointestinal bleeding from use of these drugs?
a. African Americans
b. White Americans
c. Hispanics
d. Asians
, Ans: A
Feedback:
African Americans have a documented decreased sensitivit y to pain -relieving
effects of many antiinflammatory drugs. They also have an increased risk of
developing GI adverse effects to these drugs. In general, White Americans,
Hispanics, and Asians are at lower risk f or these problems.
3. A patient, newl y diagnosed with ulcerative colitis, has been admitted to the
short-stay unit. What salicylates does the nurse anticipate will be ordered
for this patient?
a. Balsalazide (Colazal)
b. Sodium thiosalicylate (generic)
c. Choline magnesium trisalicylate (Tricosal)
d. Salsalate (Argesic)
Ans: A
Feedback:
Balsalazide is delivered intact to the colon, where it delivers a local anti -
inflammatory effect that is most effective for patients with ulcerative colitis.
Choline salicylate and salsa late are used to treat pain, fever, and
inflammation. Sodium thiosalicylate is used mainl y for episodes of acute
gout, for muscular pain, and to treat rheumatic fever.
4. The nurse is caring for a 66 -pound child with orders for choline
magnesium trisalicyl at e (Tricosal). The orders read 50 mg/kg/d PO in two
divided doses. How many milligram will the patient receive per dose?
a. 250 mg
b. 500 mg
c. 750 mg
, d. 1,000 mg
Ans: C
Feedback:
First, the nurse must determine the child’s weight in kilogram. One kg is
equal to 2.2 pounds. Divide 2.2 into 66 to equal 30 kg. Multiply 50 mg times
30 kg to equal 1,500 mg. Divide 1,500 by 2 for the divided doses, which will
equal 750 mg per dose.
5. A nurse is caring for a patient with severe rheumatoid arthritis who takes
anti-inflammatory agents on a regular basis. What medication should the
nurse question if ordered by the physician to be taken in addition to the
anti-inflammatory agent?
a. Oral antidiabetic agent
b. Calcium channel blocker
c. Beta-blocker
d. Antibiotic
Ans: C
Feedback:
Nonsteroidal anti-inflammatory drugs have the potential to decrease
antihypertensive effects from beta blockers if these drugs are taken at the
same time. Patients who receive these combinations should be monitored
closel y and appropriate dosage adjustments made if ne eded. Drug interactions
do not usuall y occur with oral antidiabetic agents, calcium channel blocking
medications, or antibiotics.
6. A nurse is assessing a patient who has been taking nonsteroidal anti -
inflammatory drugs (NSAID). What statement by the patien t indicates to
, the nurse that the patient has a good understanding of the use of this
therapy?
a. I drink a glass of wine just about every night.
b. I asked m y doctor to check for blood in my stool regularl y.
c. I do not like to swallow tablets so I crush them.
d. I drink as little water as possible when I take m y medication.
Ans: B
Feedback:
Taking certain anti -inflammatory drugs can irritate the gastric mucosa and
increase the risk of bleeding; therefore, by asking his or her doctor to check
his or her stool for ble eding, the nurse knows that the patient is aware of this.
Alcohol and crushing the tablets can interfere with anti -inflammatory
metabolism. A full glass of water should be taken with this medication to
increase absorption.
7. A salicylate has been prescribed for a 15-year-old patient who has been
diagnosed with arthritis. The mother is concerned about giving her child a
salicylate. What salicylates could the nurse tell this mother are
recommended for use in children?
a. Salsalate (Argesic)
b. Olsalazine (Dipentum)
c. Sodium thiosalicylate (generic)
d. Choline magnesium trisalicylate (Tricosal)
Ans: D
Feedback:
Aspirin and choline magnesium trisalicyl ate are the onl y salicylates
recommended for use in children. They should not be used when any risk of
Reye’s syndrome exi sts. Salsalate (Argesic), olsalazine (Dipentum), and
