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Terms in this set (120)
Climacteric phase The period of endocrinologic, somatic, and transitory psychologic
changes that occur around the time of menopause.
Early menopause LMP before age 45
Late menopause LMP after age 54
Primary ovarian insufficiency Menopause that occurs before age 40
Early menopause Persistent difference of 7 days or more in the length of
transition (stage -2) consecutive cycles.
Late menopause transition 60 or more consecutive days of amenorrhea
(stage -1)
Luteal out of phase event Explains why some perimenopausal women have elevated
(LOOP) estrogen level sometimes...In the early menopause transition,
elevated FSH levels are adequate to recruit a second follicle
which results in a follicular phase-like rise in estradiol
secretion superimposed on the mid-to-late luteal phase of
the ongoing ovulatory cycle.
, Obese women are more likely to have anovulatory cycles
Obese women and with high estradiol levels. They are also more likely to have
estradiol levels during lower premenopause yet higher postmenopause estradiol
menopause levels compared with women of normal weight. (why they
are at higher risk of endometrial cancer)
Chinese and Japanese These ethnic groups have lower estradiol levels then white, black
women and hispanic women.
stage +2 late menopause stage: 5-8 years after FMP. Somatic aging
predominates. Increased genitourinary symptoms.
Stages +1a, +1b, +1c early post menopause: 2 years after FMP. FSH rises, estradiol
decreases. VMS predominate.
Elevated FSH, LH Endocrine labs after menopause
AMH, inhibin B These hormones work during reproductive years to not
deplete follicle pool too quickly.
Phases during menopause Menstrual cycle shortenes, follicular phase compresses,
transition and PMS women spend more time in luteal phase..
symptoms
meaning more premenstrual symptoms and more frequent
menstrual periods.
How to respond if a patient many pitfalls, variable depending on the day of the cycle
requests FSH lab? you draw the lab, normal or low FSH is not helpful.
The potentially superior AMH
marker of menopause, a
lab.
DHEA Adrenal androgens: precursor hromones produced by the
(dehydroepiandrosterone) adrenal gland that are enzymatically converted to active
androgens or estrogens in peripheral tissues.
Location of estrogen Vagina, vulva, urethra, trigone of the bladder
receptors