ConceptsqofqGenetics,q10eq(Klug/Cummings/Spencer/Palladino)q
Chapterq1 IntroductionqtoqGenetics
1) Whatqisqtheqnameqofqtheqcompanyqorqinstitutionqthatqhasqaccessqtoqtheqhealth,qgenealogical,qandqg
eneticqinformationqofqapproximatelyq270,000qresidentsqofqIceland?
A) NationalqInstitutesqofqHealth
B) deCODE
C) Gattaca
D) Biogen
E) AmericanqCancerqSocietyq
Answer: B
Section: Introduction
2) Aqbiotechnologyqcompany,qdeCODE,qisqinqtheqprocessqofqcreatingqaqdatabaseqthatqcontains
.
A) theqgeneqsequencesqofqallqnewbornsqinqtheqUnitedqStatesqbeginningqinq2006
B) aqcompilationqofqallqtheqknownqgenesqinqhumansqthroughoutqtheqfreeqworld
C) health,qgenealogical,qandqgeneticqinformationqofqapproximatelyq270,000qresidentsqofqIceland
D) aqcompleteqsequenceqofqtheqhumanqgenome
E) allqtheqinformationqavailableqonqtheqhumanqgenomeqprojectq
Answer: C
Section: Introduction
3) WhyqdidqdeCODEqselectqIcelandqforqitsqambitiousqresearchqproject?
A) aqrelativelyqlowqdegreeqofqgeneticqdiversity
B) frequentqandqextensiveqmutationalqbursts
C) highqgeneticqdiversity
D) lackqofqgenealogicalqinformation
E) virtualqabsenceqofqmutationq
Answer: A
Section: Introduction
4) TheqgeneticqmaterialqDNAqconsistsqofqbasicqsubunitsqcalledq .
A) mitochondria
B) lysosomes
C) centrioles
D) nucleotides
E) Noneqofqtheqanswersqlistedqisqcorrect.q
Answer: D
Section: 1.3
1
,5) Theqimmediateqproductqofqtranscriptionqisq .
A) aqphospholipid
B) anqaminoqacid
C) aqprotein
D) aqcarbohydrate
E) RNA
Answer:
qEq
Section: 1.3
6) Inqmanyqspecies,qthereqareqtwoqrepresentativesqofqeachqchromosome.qInqsuchqspecies,qtheqchar
acteristicqnumberqofqchromosomesqisqcalledqtheq
qnumber.qItqisqusuallyqsymbolizedqasq .
A) haploid;qn
B) haploid;q2n
C) diploid;q2n
D) diploid;qn
E) Noneqofqtheqanswersqlistedqisqcorrect.q
Answer: C
Section: 1.2
7) Geneticsqisqtheqstudyqofq .
A) heredityqandqvariation
B) mutationqandqrecession
C) transcriptionqandqtranslation
D) diploidqandqhaploid
E) replicationqandqrecombinationq
Answer: A
Section: 1.2
8) Earlyqinqtheqtwentiethqcentury,qWalterqSuttonqandqTheodoreqBoveriqnotedqthatqtheqbehaviorqofqch
romosomesqduringqmeiosisqisqidenticalqtoqtheqbehaviorqofqgenesqduringqgameteqformation.qTheyqpro
posedqthatqgenesqareqcarriedqonqchromosomes,qwhichqledqtoqtheqbasisqofqtheq
.qAnswer:
ChromosomeqTheoryqofqInheritance
Section: 1.2
9) Whatqisqaqmutation?
Answer:
qAqmutationqisqanqinheritedqchangeqinqaqgene.q
Section: 1.2
10) Whatqisqaqsimpleqdefinitionqofqanqallele?qAn
swer:
qAnqalleleqisqaqvariantqform qofqaqgene.qSection
: 1.2
2
,11) Untilqtheqmid-
1940s,qmanyqscientistsqconsideredqproteinsqtoqbeqtheqlikelyqcandidatesqforqtheqgeneticqmaterial.q
Why?
Answer:
Proteinsqareqtheqmostqabundant,quniversallyqdistributedqcomponentsqinqcells.qBecauseq
ofqtheirqgreatqstructuralqandqfunctionalqdiversity,qtheyqwereqconsideredqlikelyqcandidates.
Section: 1.2
12) Nameqtheqindividualqwho,qwhileqworkingqwithqtheqgardenqpeaqinqtheqmid-
1850s,qdemonstratedqquantitativeqpatternsqofqheredityqandqdevelopedqaqtheoryqinvolvingqtheqbeha
viorqofqhereditaryqfactors.
Answer:
qGregorqMendel
qSection: 1.2
13) Whatqdoesqtheqtermqgeneticsqmean?
Answer:
Geneticsqisqaqsubdisciplineqofqbiologyqconcernedqwithqtheqstudyqofqheredityqandq
variationqatqtheqmolecular,qcellular,qdevelopmental,qorganismal,qandqpopulationalqlevels.
Section: 1.2
14) Nameqtheqsubstanceqthatqservesqasqtheqhereditaryqmaterialqinqeukaryotesqandqprokaryotes.q
Answer: DNAqorqdeoxyribonucleicqacid
Section: 1.2
15) Nameqtwoqindividualsqwhoqprovidedqtheqconceptualqbasisqforqourqpresentqunderstandingqthatq
genesqareqonqchromosomes.
Answer:
qWalterqSuttonqandqTheodoreqBoveriq
Section: 1.2
16) Whatqtermqisqusedqtoqdescribeqtheqfactqthatqdifferentqgenesqinqanqorganismqoftenqprovideqd
ifferencesqinqobservableqfeatures?
Answer:
qphenotype
qSection: 1.2
17) AqfundamentalqpropertyqofqDNA'sqnitrogenousqbasesqthatqisqnecessaryqforqtheq
double-strandedqnatureqofqitsqstructureqisq .
Answer:
qcomplementarityq
Section: 1.3
18) RecombinantqDNAqtechnologyqisqdependentqonqaqparticularqclassqofqenzymes,qknownqas
,qthatqcutqDNAqatqspecificqnucleotideqsequences.q
Answer: restrictionqenzymes
Section: 1.4
3
, 19) Nameqtheqbotanistqwho,qinq1900,qrediscoveredqtheqworkqofqGregorqMendel.q
Answer: CarlqCorrens
Section: 1.2
4
Chapterq1 IntroductionqtoqGenetics
1) Whatqisqtheqnameqofqtheqcompanyqorqinstitutionqthatqhasqaccessqtoqtheqhealth,qgenealogical,qandqg
eneticqinformationqofqapproximatelyq270,000qresidentsqofqIceland?
A) NationalqInstitutesqofqHealth
B) deCODE
C) Gattaca
D) Biogen
E) AmericanqCancerqSocietyq
Answer: B
Section: Introduction
2) Aqbiotechnologyqcompany,qdeCODE,qisqinqtheqprocessqofqcreatingqaqdatabaseqthatqcontains
.
A) theqgeneqsequencesqofqallqnewbornsqinqtheqUnitedqStatesqbeginningqinq2006
B) aqcompilationqofqallqtheqknownqgenesqinqhumansqthroughoutqtheqfreeqworld
C) health,qgenealogical,qandqgeneticqinformationqofqapproximatelyq270,000qresidentsqofqIceland
D) aqcompleteqsequenceqofqtheqhumanqgenome
E) allqtheqinformationqavailableqonqtheqhumanqgenomeqprojectq
Answer: C
Section: Introduction
3) WhyqdidqdeCODEqselectqIcelandqforqitsqambitiousqresearchqproject?
A) aqrelativelyqlowqdegreeqofqgeneticqdiversity
B) frequentqandqextensiveqmutationalqbursts
C) highqgeneticqdiversity
D) lackqofqgenealogicalqinformation
E) virtualqabsenceqofqmutationq
Answer: A
Section: Introduction
4) TheqgeneticqmaterialqDNAqconsistsqofqbasicqsubunitsqcalledq .
A) mitochondria
B) lysosomes
C) centrioles
D) nucleotides
E) Noneqofqtheqanswersqlistedqisqcorrect.q
Answer: D
Section: 1.3
1
,5) Theqimmediateqproductqofqtranscriptionqisq .
A) aqphospholipid
B) anqaminoqacid
C) aqprotein
D) aqcarbohydrate
E) RNA
Answer:
qEq
Section: 1.3
6) Inqmanyqspecies,qthereqareqtwoqrepresentativesqofqeachqchromosome.qInqsuchqspecies,qtheqchar
acteristicqnumberqofqchromosomesqisqcalledqtheq
qnumber.qItqisqusuallyqsymbolizedqasq .
A) haploid;qn
B) haploid;q2n
C) diploid;q2n
D) diploid;qn
E) Noneqofqtheqanswersqlistedqisqcorrect.q
Answer: C
Section: 1.2
7) Geneticsqisqtheqstudyqofq .
A) heredityqandqvariation
B) mutationqandqrecession
C) transcriptionqandqtranslation
D) diploidqandqhaploid
E) replicationqandqrecombinationq
Answer: A
Section: 1.2
8) Earlyqinqtheqtwentiethqcentury,qWalterqSuttonqandqTheodoreqBoveriqnotedqthatqtheqbehaviorqofqch
romosomesqduringqmeiosisqisqidenticalqtoqtheqbehaviorqofqgenesqduringqgameteqformation.qTheyqpro
posedqthatqgenesqareqcarriedqonqchromosomes,qwhichqledqtoqtheqbasisqofqtheq
.qAnswer:
ChromosomeqTheoryqofqInheritance
Section: 1.2
9) Whatqisqaqmutation?
Answer:
qAqmutationqisqanqinheritedqchangeqinqaqgene.q
Section: 1.2
10) Whatqisqaqsimpleqdefinitionqofqanqallele?qAn
swer:
qAnqalleleqisqaqvariantqform qofqaqgene.qSection
: 1.2
2
,11) Untilqtheqmid-
1940s,qmanyqscientistsqconsideredqproteinsqtoqbeqtheqlikelyqcandidatesqforqtheqgeneticqmaterial.q
Why?
Answer:
Proteinsqareqtheqmostqabundant,quniversallyqdistributedqcomponentsqinqcells.qBecauseq
ofqtheirqgreatqstructuralqandqfunctionalqdiversity,qtheyqwereqconsideredqlikelyqcandidates.
Section: 1.2
12) Nameqtheqindividualqwho,qwhileqworkingqwithqtheqgardenqpeaqinqtheqmid-
1850s,qdemonstratedqquantitativeqpatternsqofqheredityqandqdevelopedqaqtheoryqinvolvingqtheqbeha
viorqofqhereditaryqfactors.
Answer:
qGregorqMendel
qSection: 1.2
13) Whatqdoesqtheqtermqgeneticsqmean?
Answer:
Geneticsqisqaqsubdisciplineqofqbiologyqconcernedqwithqtheqstudyqofqheredityqandq
variationqatqtheqmolecular,qcellular,qdevelopmental,qorganismal,qandqpopulationalqlevels.
Section: 1.2
14) Nameqtheqsubstanceqthatqservesqasqtheqhereditaryqmaterialqinqeukaryotesqandqprokaryotes.q
Answer: DNAqorqdeoxyribonucleicqacid
Section: 1.2
15) Nameqtwoqindividualsqwhoqprovidedqtheqconceptualqbasisqforqourqpresentqunderstandingqthatq
genesqareqonqchromosomes.
Answer:
qWalterqSuttonqandqTheodoreqBoveriq
Section: 1.2
16) Whatqtermqisqusedqtoqdescribeqtheqfactqthatqdifferentqgenesqinqanqorganismqoftenqprovideqd
ifferencesqinqobservableqfeatures?
Answer:
qphenotype
qSection: 1.2
17) AqfundamentalqpropertyqofqDNA'sqnitrogenousqbasesqthatqisqnecessaryqforqtheq
double-strandedqnatureqofqitsqstructureqisq .
Answer:
qcomplementarityq
Section: 1.3
18) RecombinantqDNAqtechnologyqisqdependentqonqaqparticularqclassqofqenzymes,qknownqas
,qthatqcutqDNAqatqspecificqnucleotideqsequences.q
Answer: restrictionqenzymes
Section: 1.4
3
, 19) Nameqtheqbotanistqwho,qinq1900,qrediscoveredqtheqworkqofqGregorqMendel.q
Answer: CarlqCorrens
Section: 1.2
4
