NR508 | NR 508 WEEK 3 EXAM | ADVANCED
PHARMACOLOGY EXAM | QUESTIONS AND
CORRECT ANSWERS | 2025/2026 LATEST
GUIDE | CHAMBERLAIN
What is a common side effect concern with hypertensive medications
and all individuals, but especially the elderly?
1. Risk of falls
2. Triggering of a hypertensive crisis
3. Erectile priapism
4. Risk for bladder cancer development - Correct Answer - 1. Risk of falls
Ray has been diagnosed with hypertension and an angiotensin-
converting enzyme inhibitor is determined to be needed. Prior to
prescribing this drug, the NP should assess for:
1. Hypokalemia
2. Impotence
3. Decreased renal function
4. Inability to concentrate - Correct Answer - 3. Decreased renal function
Angiotensin-converting enzyme inhibitors are the drug of choice in
treating hypertension in diabetic patients because they:
1. Improve insulin sensitivity
,2. Improve renal hemodynamics
3. Reduce the production of angiotensin II
4. All of the above - Correct Answer - 4. All of the above
A potentially life-threatening adverse response to angiotensin-converting
enzyme inhibitors is angioedema. Which of the following statements is
true about this adverse response?
1. Swelling of the tongue or hoarseness are the most common
symptoms.
2. It appears to be related to the decrease in aldosterone production.
3. Presence of a dry, hacky cough indicates a high risk for this adverse
response.
4. Because it takes time to build up a blood level, it occurs after being on
the drug for about 1 week. - Correct Answer - 1. Swelling of the tongue
or hoarseness are the most common symptoms.
Angiotensin-converting enzyme inhibitors are useful in a variety of
disorders. Which of the following statements are true about both its
usefulness in the disorder and the reason for its use?
1. Stable angina because it decreases the thickening of vascular walls
due to decreased modified release.
2. Heart failure because it reduces remodeling of injured myocardial
tissues.
3. Both 1 and 2 are true and the reasons are correct.
,4. Both 1 and 2 are true but the reasons are wrong.
5. Neither 1 nor 2 are true. - Correct Answer - 4. Both 1 and 2 are true
but the reasons are wrong.
Despite good blood pressure control, an NP might change a patient's
drug from an angiotensin-converting enzyme (ACE) inhibitor to an
angiotensin II receptor blocker (ARB) because the ARB:
1. Is stronger than the ACE inhibitor
2. Does not produce a dry, hacky cough
3. Has no effect on the renal system
4. Reduces sodium and water retention - Correct Answer - 2. Does not
produce a dry, hacky cough
While taking an angiotensin II receptor blocker (ARB), patients need to
avoid certain over-the-counter drugs without first consulting the provider
because:
1. Cimetidine is metabolized by the CYP 3A4 isoenzymes
2. Nonsteroidal anti-inflammatory drugs reduce prostaglandin levels
3. Both 1 and 2
4. Neither 1 nor 2 - Correct Answer - 3. Both 1 and 2
Laboratory monitoring for patients on angiotensin-converting enzyme
inhibitors or angiotensin II receptor blockers should include:
, 1. White blood cell counts with the drug dosage increased for elevations
above 10,000 feet
2. Liver function tests with the drug dosage stopped for alanine
aminotransferase values twice that of normal
3. Serum creatinine levels with the drug dosage reduced for values
greater than 2.5 mg/dL
4. Serum glucose levels with the drug dosage increased for levels
greater than 120 mg/dL - Correct Answer - 3. Serum creatinine levels
with the drug dosage reduced for values greater than 2.5 mg/dL
Jacob has hypertension, for which a calcium channel blocker has been
prescribed. This drug helps control blood pressure because it:
1. Decreases the amount of calcium inside the cell
2. Reduces stroke volume
3. Increases the activity of the Na+/K+/ATPase pump indirectly
4. Decreases heart rate - Correct Answer - 1. Decreases the amount of
calcium inside the cell
Which of the following adverse effects may occur due to a
dihydropyridine-type calcium channel blocker?
1. Bradycardia
2. Hepatic impairment
3. Increased contractility
PHARMACOLOGY EXAM | QUESTIONS AND
CORRECT ANSWERS | 2025/2026 LATEST
GUIDE | CHAMBERLAIN
What is a common side effect concern with hypertensive medications
and all individuals, but especially the elderly?
1. Risk of falls
2. Triggering of a hypertensive crisis
3. Erectile priapism
4. Risk for bladder cancer development - Correct Answer - 1. Risk of falls
Ray has been diagnosed with hypertension and an angiotensin-
converting enzyme inhibitor is determined to be needed. Prior to
prescribing this drug, the NP should assess for:
1. Hypokalemia
2. Impotence
3. Decreased renal function
4. Inability to concentrate - Correct Answer - 3. Decreased renal function
Angiotensin-converting enzyme inhibitors are the drug of choice in
treating hypertension in diabetic patients because they:
1. Improve insulin sensitivity
,2. Improve renal hemodynamics
3. Reduce the production of angiotensin II
4. All of the above - Correct Answer - 4. All of the above
A potentially life-threatening adverse response to angiotensin-converting
enzyme inhibitors is angioedema. Which of the following statements is
true about this adverse response?
1. Swelling of the tongue or hoarseness are the most common
symptoms.
2. It appears to be related to the decrease in aldosterone production.
3. Presence of a dry, hacky cough indicates a high risk for this adverse
response.
4. Because it takes time to build up a blood level, it occurs after being on
the drug for about 1 week. - Correct Answer - 1. Swelling of the tongue
or hoarseness are the most common symptoms.
Angiotensin-converting enzyme inhibitors are useful in a variety of
disorders. Which of the following statements are true about both its
usefulness in the disorder and the reason for its use?
1. Stable angina because it decreases the thickening of vascular walls
due to decreased modified release.
2. Heart failure because it reduces remodeling of injured myocardial
tissues.
3. Both 1 and 2 are true and the reasons are correct.
,4. Both 1 and 2 are true but the reasons are wrong.
5. Neither 1 nor 2 are true. - Correct Answer - 4. Both 1 and 2 are true
but the reasons are wrong.
Despite good blood pressure control, an NP might change a patient's
drug from an angiotensin-converting enzyme (ACE) inhibitor to an
angiotensin II receptor blocker (ARB) because the ARB:
1. Is stronger than the ACE inhibitor
2. Does not produce a dry, hacky cough
3. Has no effect on the renal system
4. Reduces sodium and water retention - Correct Answer - 2. Does not
produce a dry, hacky cough
While taking an angiotensin II receptor blocker (ARB), patients need to
avoid certain over-the-counter drugs without first consulting the provider
because:
1. Cimetidine is metabolized by the CYP 3A4 isoenzymes
2. Nonsteroidal anti-inflammatory drugs reduce prostaglandin levels
3. Both 1 and 2
4. Neither 1 nor 2 - Correct Answer - 3. Both 1 and 2
Laboratory monitoring for patients on angiotensin-converting enzyme
inhibitors or angiotensin II receptor blockers should include:
, 1. White blood cell counts with the drug dosage increased for elevations
above 10,000 feet
2. Liver function tests with the drug dosage stopped for alanine
aminotransferase values twice that of normal
3. Serum creatinine levels with the drug dosage reduced for values
greater than 2.5 mg/dL
4. Serum glucose levels with the drug dosage increased for levels
greater than 120 mg/dL - Correct Answer - 3. Serum creatinine levels
with the drug dosage reduced for values greater than 2.5 mg/dL
Jacob has hypertension, for which a calcium channel blocker has been
prescribed. This drug helps control blood pressure because it:
1. Decreases the amount of calcium inside the cell
2. Reduces stroke volume
3. Increases the activity of the Na+/K+/ATPase pump indirectly
4. Decreases heart rate - Correct Answer - 1. Decreases the amount of
calcium inside the cell
Which of the following adverse effects may occur due to a
dihydropyridine-type calcium channel blocker?
1. Bradycardia
2. Hepatic impairment
3. Increased contractility
