BASIC AND CLINICAL PHARMACOLOGY 15THEDITION KATZUNG TREVOR TEST BANK

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BASIC AND CLINICAL PHARMACOLOGY 15TH EDITION KAT
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ZUNG TREVOR TEST BANK
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INCLUSIVErOFrCHAPTERSr1-66rCOMPLETErWITHrEXPLAINEDrANSWERS

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Basic and Clinical Pharmacology 15th Edition Katzung Trevor Test Bank
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Chapterr1.rIntroduction:rTherNaturerofrDrugsr&rDrugrDevelopmentr&rRegulation


1.
Arnurserworkingrinrradiologyradministersriodinertorarpatientrwhorisrhavingrarc
omputedrtomographyr(CT)rscan.rThernurserworkingronrtheroncologyrunitradmin
istersrchemotherapyrtorpatientsrwhorhavercancer.rAtrtherPublicrHealthrDepartme
nt,rarnurseradministersrarmeasles-mumps-rubellar(MMR)rvaccinertorar14-month-
oldrchildrasrarroutinerimmunization.rWhichrbranchrofrpharmacologyrbestrdescri
besrtheractionsrofrallrthreer nurses?
A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
Ans: B
Feedback:

Pharmacologyrisrtherstudyrofrtherbiologicreffectsrofrchemicals.rNursesrarerinvol
vedrwithrclinicalrpharmacologyrorrpharmacotherapeutics,rwhichrisrarbranchrofrp
harmacologyrthatrdealsrwithrtherusesrofrdrugsrtortreat,rprevent,randrdiagnoserdis
ease.rTherradiologyrnurserisradministeringrardrugrtorhelprdiagnoserardisease.rTh
eroncologyrnurserisradministeringrardrugrtorhelprtreatrardisease.rPharmacoecono
micsrincludesranyrcostsrinvolvedrinrdrugrtherapy.
Pharmacodynamicsrinvolvesrhowrardrugraffectsrtherbodyrandrpharmacokineticsri
srhowrtherbodyractsronrtherbody.



2.
WhenrinvolvedrinrphaserIIIrdrugrevaluationrstudies,rwhatr
responsibilitiesrwouldrthernurserhave?
A) Workingrwithranimalsrwhorarergivenrexperimentalr drugs
B) Choosingrappropriaterpatientsrtorberinvolvedrinrtherdrugr study
C) Monitoringrandrobservingrpatientsrcloselyrforradverser effects
D) Conductingrresearchrtordeterminereffectivenessrofrther drug

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Ans: C
Feedback:

PhaserIIIrstudiesrinvolveruserofrardrugrinrarvastrclinicalrpopulationrinrwhichrpatie
ntsrareraskedrtorrecordranyrsymptomsrtheyrexperiencerwhilertakingrtherdrugs.rN
ursesrmayrberresponsiblerforrhelpingrcollectrandranalyzertherinformationrtorbers
haredrwithrtherFoodrandrDrugrAdministrationr(FDA)rbutrwouldrnotrconductrrese
archrindependentlyrbecausernursesrdornotrprescribermedications.rUserofranimal
srinrdrugrtestingrisrdonerinrtherpreclinicalrtrials.rSelectrpatientsrwhorarerinvolved
rinrphaserIIrstudiesrtorparticipaterinrstudiesrwherertherparticipantsrhavertherdisea

sertherdrugrisrintendedrtortreat.rTheserpatientsrarermonitoredrcloselyrforrdrugract
ionrandradversereffects.rPhaserIrstudiesrinvolverhealthyrhumanrvolunteersrwhora
rerusuallyrpaidrforrtheirrparticipation.rNursesrmayrobserverforradversereffectsran
drtoxicity.




3.
Arphysicianrhasrorderedrintramuscularr(IM)rinjectionsrofrmorphine,rarnarcoti
c,reveryr4rhoursrasrneededrforrpainrinrarmotorrvehicleraccidentrvictim.rThernurser
israwarerthisrdrugrhasrarhighrabuserpotential.rUnderrwhatrcategoryrwouldrmorph
inerberclassified?
A) SchedulerI
B) SchedulerII
C) SchedulerIII
D) SchedulerIV
Ans: B
Feedback:

NarcoticsrwithrarhighrabuserpotentialrarerclassifiedrasrSchedulerIIrdrugsrbecau
serofrsevererdependencerliability.rSchedulerIrdrugsrhaverhighrabuserpotentialra
ndrnoracceptedrmedicalruse.rSchedulerIIIrdrugsrhaverarlesserrabuserpotentialrth
anrIIrandranracceptedrmedicalruse.rSchedulerIVrdrugsrhaverlowrabuserpotentialr
andrlimitedrdependencerliability.

4.
Whatrconceptrisrconsideredrwhenrgenericrdrugsrarersubstitutedrforrbrandr
namerdrugs?
A) Bioavailability

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