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Test Bank for Molecular Biology of the Cell, 7th Edition by Bruce Alberts.pdf

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Test Bank for Molecular Biology of the Cell, 7th Edition by Bruce A

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Lodish • Berk • Kaiser • Krieger • Scott • Bretscher •Ploegh • Matsudaira
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• MOLECULARCELL q q




BIOLOGY
• SIXTH EDITION q




• CHAPTER 3 q




• Protein Structure and Function
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© 2008 W. H. Freeman and Company
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, Human signali
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Ribbon diagram
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,Conformations Str q
Functional classes:
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uctural proteins Sc
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Structural proteins T
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affold protein Tran
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ransport proteins Re
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sport protein Regul
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gulatoryproteins M
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atoryprotein enzy
otor proteins
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Different conformation = different function
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, Hierarchical structure of proteins
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Proteins are single, unbranched chains of amino acid monomers
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There are 20 different amino acids; All amino acids have the same general structur
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e but the side chain (R group) of each is different
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A protein’s amino acid sequence determines its three-
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dimensional structure (conformation) q q




In turn, a protein’s structure determines the function of that protein
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pK2 H pK1
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H3N C COO

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