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NURSE PRESCRIBERS, 5TH EDITION TEST BANK FINAL EXAM QUESTI
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Chapter 18. Drugs Affecting the Endocrine System: Pancreatic Hormones and Antidiabetic Dr
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ugs
• Patients with cystic fibrosis are often prescribed enzyme replacement for pancreatic secreti
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ons. Each replacement drug has lipase, protease, and amylase components, but the drug is p
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rescribed in units of: f f f
a. Lipase
b. Protease
c. Amylase
d. Pancreatin
• Brands of pancreatic enzyme replacement drugs are:
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a. Bioequivalent
b. About the same in cost per unit of lipase across brands
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c. Able to be interchanged between generic and brand-name products to reduce cost
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d. None of the above f f f
• When given subcutaneously, how long until neutral protamine Hagedorn insulin begins to take e
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ffect (onsetof action) after administration?
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a. 15 to 30 minutes f f f
b. 60 to 90 minutes f f f
c. 3 to 4 hours f f f
d. 6 to 8 hours f f f
• Hypoglycemia can result from the action of either insulin or an oral hypoglycemic. Signs and sy
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NURS 60441 PHARMACOTHERAPEUTICS FOR ADVANCED PRACTICE
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NURSE PRESCRIBERS, 5TH EDITION TEST BANK FINAL EXAM QUESTI
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,NURS 60441 PHARMACOTHERAPEUTICS FOR ADVANCED PRACTICE
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NURSE PRESCRIBERS, 5TH EDITION TEST BANK FINAL EXAM QUESTI
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mptoms ofhypoglycemia include:
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a. “Fruity” breath odor and rapid respiration f f f f f
b. Diarrhea, abdominal pain, weight loss, and hypert f f f f f f
ensionc. Dizziness, confusion, diaphoresis, and tach
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ycardia
d. Easy bruising, palpitations, cardiac dysrhythmias, and coma
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• Nonselective beta blockers and alcohol create serious drug interactions with insulin because they:
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a. Increase blood glucose levels f f f
b. Produce unexplained diaphoresis f f
c. Interfere with the ability of the body to metabolize gl f f f f f f f f f
ucosed. Mask the signs and symptoms of altered glucose
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f levels
• Lispro is an insulin analogue produced by recombinant DNA technology. Wh
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ich of thefollowing statements about this form of insulin is NOT true?
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a. Optimal time of preprandial injection is 15 minutes. f f f f f f f
b. Duration of action is increased when the dose is increased. f f f f f f f f f
c. It is compatible with neutral protamine Hagedorn insulin.
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d. It has no pronounced peak.
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• The decision may be made to switch from twice daily neutral protamine Hagedor
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n (NPH)insulin to insulin glargine to improve glycemia control throughout the d
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ay. If this is done:
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NURS 60441 PHARMACOTHERAPEUTICS FOR ADVANCED PRACTICE
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NURSE PRESCRIBERS, 5TH EDITION TEST BANK FINAL EXAM QUESTI
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,NURS 60441 PHARMACOTHERAPEUTICS FOR ADVANCED PRACTICE
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NURSE PRESCRIBERS, 5TH EDITION TEST BANK FINAL EXAM QUESTI
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a. The initial dose of glargine is reduced by 20% to avoid hypoglycemia.
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b. The initial dose of glargine is 2 to 10 units per day.
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c. Patients who have been on high doses of NPH will need tests for insulin antibodies.
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d. Obese patients may require more than 100 units per day.
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• When blood glucose levels are difficult to control in type 2 diabetes some form of ins
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ulin maybe added to the treatment regimen to control blood glucose and limit compli
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cation risks. f
Which ofthe following statements is accurate based on research?
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a. Premixed insulin analogues are better at lowering HbA1C and have less f f f f f f f f f f f
risk forhypoglycemia.
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b. Premixed insulin analogues and the newer premixed insulins are associated w f f f f f f f f f f
ith moreweight gain than the oral antidiabetic agents.
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c. Newer premixed insulins are better at lowering HbA1C and postprandia
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l glucoselevels than long-acting insulins.
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d. Patients who are not controlled on oral agents and have postprandial hyperg
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lycemiacan have neutral protamine Hagedorn insulin added at bedtime.
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• Metformin is a primary choice of drug to treat hyperglycemia in type 2 diabetes because it:
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a. Substitutes for insulin usually secreted by the pa f f f f f f f
ncreasb. Decreases glycogenolysis by the liver
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c. Increasesfthefreleasefoffinsulinffromfbetafcells
d. Decreasesfperipheralfglucosefutilization
• Prior to prescribing metformin, the provider should:
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NURS 60441 PHARMACOTHERAPEUTICS FOR ADVANCED PRACTICE
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NURSE PRESCRIBERS, 5TH EDITION TEST BANK FINAL EXAM QUESTI
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ONS AND ANSWERS BEST RATED A+ GUARANTEED SUCCESS LATEST
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, NURS 60441 PHARMACOTHERAPEUTICS FOR ADVANCED PRACTICE
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NURSE PRESCRIBERS, 5TH EDITION TEST BANK FINAL EXAM QUESTI
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a. Draw a serum creatinine to assess renal function
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b. Try the patient on insulin
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c. Tell the patient to increase iodine intake
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d. Have the patient stop taking any sulfonylurea to avoid dangerous drug interactions
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• The action of “gliptins” is different from other antidiabetic agents because they:
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a. Have a low risk for hypoglycemia f f f f f
b. Are not associated with weight gain
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c. Close ATP-dependent potassium channels in the beta cell
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d. Act on the incretin system to indirectly increase insulin production
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• Sitagliptin has been approved for: f f f f
a. Monotherapy in once-daily doses f f f
b. Combination therapy with metformin f f f
c. Both 1 and 2 f f f f
d. Neither 1 nor 2 f f f
• GLP-1 agonists: f
a. Directly bind to a receptor in the pancreatic beta cell f f f f f f f f f
b. Have been approved for monotherapy f f f f
c. Speed gastric emptying to decrease appetite f f f f f
d. Can be given orally once daily
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• Avoid concurrent administration of exenatide with which of the following drugs?
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a. Digoxin
NURS 60441 PHARMACOTHERAPEUTICS FOR ADVANCED PRACTICE
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NURSE PRESCRIBERS, 5TH EDITION TEST BANK FINAL EXAM QUESTI
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ONS AND ANSWERS BEST RATED A+ GUARANTEED SUCCESS LATEST
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UPDATE 2022 f