Psychopharmacology Drugs the Brain And Behavior 3rd Edition meyer Nursing T
x x x x x x x x x x
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x
,Psychopharmacology Drugs the Brain And Behavior 3rd Edition meyer Nursing T
x x x x x x x x x x
est Bank
x
Test Bank
x
toxaccompany
Psychopharmacology, Third Edition x x
Meyerx•xQuenzer
Chapter 1: Principles of Pharmacology
x x x x
MultiplexChoice
1. x
refer(s)xtoxspecificxmolecularxchangesxthatxoccurxwhenxaxdrugxbindsxtoxaxparticularxtarg
etxsitexorxreceptor,xwhile
arexthexresultingxwidespreadxalterationsxinxfunction.
a. Drugxaction;xtherapeuticxeffects
b. Sidexeffects;xdrugxeffects
c. Therapeuticxeffects;xsidexeffects
d. Drugxaction;xdrugxeffects
Answer:xd
TextbookxReference:xPharmacology:xThexSciencexofxDrugxAction
2. Afterxdrugxadministrationxhasxoccurred,xthexamountxofxdrugxinxthexbloodxthatxisxfreextoxb
indxatxspecificxtargetxsitesxisxreferredxtoxas
a. thextherapeuticxdose.
b. first-passxeffects.
c. bioavailability.
d. ED50.
Answer:xc
TextbookxReference:xPharmacokineticxFactorsxDeterminingxDrugxAction
3. Thexspecificxmolecularxchangesxthatxoccurxwhenxaxdrugxbindsxtoxaxparticularxtargetxsitexo
rxreceptorxarexreferredxtoxas
a. drugxeffects.
b. drugxaction.
c. sidexeffects.
d. placeboxeffects.
Answer:xb
TextbookxReference:xPharmacology:xThexSciencexofxDrugxAction
4. Whichxofxthexfollowingxisxnotxaxpossiblexexplanationxforxplaceboxeffects?
a. Pavlovianxconditioning
b. Geneticxvariation
c. Drugxcompetition
d. Expectationxofxoutcome
Answer:xc
TextbookxReference:xPharmacology:xThexSciencexofxDrugxAction
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5. The administrationxofxoxytocinxhasxbeenxproposedxasxaxtreatmentxforxautism.
a. intravenous
b. oral
c. intranasal
d. intracerebral
Answer:xc
TextbookxReference:xPharmacokineticxFactorsxDeterminingxDrugxAction
6. Whichxfactorxdoesxnotxaffectxthexpharmacokineticsxofxaxdrug?
a. Routexofxadministration
b. Lipidxsolubility
c. Depotxbinding
d. Drugxaction
Answer:xd
TextbookxReference:xPharmacokineticxFactorsxDeterminingxDrugxAction
7. First-passxmetabolismxoccursxwhenxdrugsxarextaken
a. orally.
b. intravenously.
c. subcutaneously.
d. nasally.
Answer:xa
TextbookxReference:xPharmacokineticxFactorsxDeterminingxDrugxAction
8. Thexareaxpostremaxisxonexareaxinxthexbrainxwherexthe isxnotxcomplete.
a. cerebrospinalxfluid
b. blood–brainxbarrier
c. choroidxplexus
d. phospholipidxmembrane
Answer:xb
TextbookxReference:xPharmacokineticxFactorsxDeterminingxDrugxAction
9. First-passxmetabolismxoccursxwithxorallyxadministeredxdrugsxbecause
a. theirxabsorptionxisxslowedxbyxfood.
b. drugsxabsorbedxintoxthexbloodstreamxfromxthexstomachxgoxtoxthexliverxonxthexwayxtoxg
eneralxcirculation.
c. drugsxmustxfirstxsurvivexthexacidicxenvironmentxofxthexstomach.
d. salivaryxenzymesxinxthexmouthxbeginxthexprocessxofxmetabolism.
Answer:xb
TextbookxReference:xPharmacokineticxFactorsxDeterminingxDrugxAction
10. Toxicxsubstancesxinxthexbloodxtriggerxaxvomitingxresponsexbyxactivatingxthe
a. blood–brainxbarrier.
b. choroidxplexus.
c. areaxpostrema.
d. medianxeminence.
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, Psychopharmacology Drugs the Brain And Behavior 3rd Edition meyer Nursing T
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x
Answer:xc
TextbookxReference:xPharmacokineticxFactorsxDeterminingxDrugxAction
11. Drugsxadministeredx_ havexthexmostxrapidxonsetxofxaction.
a. subcutaneously
b. intramuscularly
c. orally
d. intravenously
Answer:xd
TextbookxReference:xPharmacokineticxFactorsxDeterminingxDrugxAction
12. Ionizationxofxaxdrugxdependsxonxthe ofxthexsolutionxandxthe
ofxthexdrug.
a. pH;xpKa
b. pKa;xpH
c. concentration;xlipidxsolubility
d. pH;xconcentration
Answer:xa
TextbookxReference:xPharmacokineticxFactorsxDeterminingxDrugxAction
13. Thexabsorptionxofxaxdrugxdependsxonxallxofxthexfollowingxexcept
a. lipidxsolubility.
b. ionization.
c. bodyxtemperature.
d. thexconcentrationxofxthexdrug.
Answer:xc
TextbookxReference:xPharmacokineticxFactorsxDeterminingxDrugxAction
14. Drugsxthatxare shouldxbexavoidedxbyxwomenxofxchildbearingxage.
a. teratogenic
b. ablextoxcrossxthexplacentalxbarrier
c. psychoactive
d. highlyxlipid-soluble
Answer:xa
TextbookxReference:xPharmacokineticxFactorsxDeterminingxDrugxAction
15. Agentsxthatxinducexdevelopmentalxabnormalitiesxinxaxfetusxarexknownxas
a. psychoactivexdrugs.
b. illicitxdrugs.
c. teratogens.
d. placentalxdrugs.
Answer:xc
TextbookxReference:xPharmacokineticxFactorsxDeterminingxDrugxAction
16. Depotxbindingxisxsaidxtoxoccurxwhenxdrugs
a. bindxtoxtheirxtargetxsites.
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x
,Psychopharmacology Drugs the Brain And Behavior 3rd Edition meyer Nursing T
x x x x x x x x x x
est Bank
x
Test Bank
x
toxaccompany
Psychopharmacology, Third Edition x x
Meyerx•xQuenzer
Chapter 1: Principles of Pharmacology
x x x x
MultiplexChoice
1. x
refer(s)xtoxspecificxmolecularxchangesxthatxoccurxwhenxaxdrugxbindsxtoxaxparticularxtarg
etxsitexorxreceptor,xwhile
arexthexresultingxwidespreadxalterationsxinxfunction.
a. Drugxaction;xtherapeuticxeffects
b. Sidexeffects;xdrugxeffects
c. Therapeuticxeffects;xsidexeffects
d. Drugxaction;xdrugxeffects
Answer:xd
TextbookxReference:xPharmacology:xThexSciencexofxDrugxAction
2. Afterxdrugxadministrationxhasxoccurred,xthexamountxofxdrugxinxthexbloodxthatxisxfreextoxb
indxatxspecificxtargetxsitesxisxreferredxtoxas
a. thextherapeuticxdose.
b. first-passxeffects.
c. bioavailability.
d. ED50.
Answer:xc
TextbookxReference:xPharmacokineticxFactorsxDeterminingxDrugxAction
3. Thexspecificxmolecularxchangesxthatxoccurxwhenxaxdrugxbindsxtoxaxparticularxtargetxsitexo
rxreceptorxarexreferredxtoxas
a. drugxeffects.
b. drugxaction.
c. sidexeffects.
d. placeboxeffects.
Answer:xb
TextbookxReference:xPharmacology:xThexSciencexofxDrugxAction
4. Whichxofxthexfollowingxisxnotxaxpossiblexexplanationxforxplaceboxeffects?
a. Pavlovianxconditioning
b. Geneticxvariation
c. Drugxcompetition
d. Expectationxofxoutcome
Answer:xc
TextbookxReference:xPharmacology:xThexSciencexofxDrugxAction
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,Psychopharmacology Drugs the Brain And Behavior 3rd Edition meyer Nursing T
x x x x x x x x x x
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x
5. The administrationxofxoxytocinxhasxbeenxproposedxasxaxtreatmentxforxautism.
a. intravenous
b. oral
c. intranasal
d. intracerebral
Answer:xc
TextbookxReference:xPharmacokineticxFactorsxDeterminingxDrugxAction
6. Whichxfactorxdoesxnotxaffectxthexpharmacokineticsxofxaxdrug?
a. Routexofxadministration
b. Lipidxsolubility
c. Depotxbinding
d. Drugxaction
Answer:xd
TextbookxReference:xPharmacokineticxFactorsxDeterminingxDrugxAction
7. First-passxmetabolismxoccursxwhenxdrugsxarextaken
a. orally.
b. intravenously.
c. subcutaneously.
d. nasally.
Answer:xa
TextbookxReference:xPharmacokineticxFactorsxDeterminingxDrugxAction
8. Thexareaxpostremaxisxonexareaxinxthexbrainxwherexthe isxnotxcomplete.
a. cerebrospinalxfluid
b. blood–brainxbarrier
c. choroidxplexus
d. phospholipidxmembrane
Answer:xb
TextbookxReference:xPharmacokineticxFactorsxDeterminingxDrugxAction
9. First-passxmetabolismxoccursxwithxorallyxadministeredxdrugsxbecause
a. theirxabsorptionxisxslowedxbyxfood.
b. drugsxabsorbedxintoxthexbloodstreamxfromxthexstomachxgoxtoxthexliverxonxthexwayxtoxg
eneralxcirculation.
c. drugsxmustxfirstxsurvivexthexacidicxenvironmentxofxthexstomach.
d. salivaryxenzymesxinxthexmouthxbeginxthexprocessxofxmetabolism.
Answer:xb
TextbookxReference:xPharmacokineticxFactorsxDeterminingxDrugxAction
10. Toxicxsubstancesxinxthexbloodxtriggerxaxvomitingxresponsexbyxactivatingxthe
a. blood–brainxbarrier.
b. choroidxplexus.
c. areaxpostrema.
d. medianxeminence.
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, Psychopharmacology Drugs the Brain And Behavior 3rd Edition meyer Nursing T
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x
Answer:xc
TextbookxReference:xPharmacokineticxFactorsxDeterminingxDrugxAction
11. Drugsxadministeredx_ havexthexmostxrapidxonsetxofxaction.
a. subcutaneously
b. intramuscularly
c. orally
d. intravenously
Answer:xd
TextbookxReference:xPharmacokineticxFactorsxDeterminingxDrugxAction
12. Ionizationxofxaxdrugxdependsxonxthe ofxthexsolutionxandxthe
ofxthexdrug.
a. pH;xpKa
b. pKa;xpH
c. concentration;xlipidxsolubility
d. pH;xconcentration
Answer:xa
TextbookxReference:xPharmacokineticxFactorsxDeterminingxDrugxAction
13. Thexabsorptionxofxaxdrugxdependsxonxallxofxthexfollowingxexcept
a. lipidxsolubility.
b. ionization.
c. bodyxtemperature.
d. thexconcentrationxofxthexdrug.
Answer:xc
TextbookxReference:xPharmacokineticxFactorsxDeterminingxDrugxAction
14. Drugsxthatxare shouldxbexavoidedxbyxwomenxofxchildbearingxage.
a. teratogenic
b. ablextoxcrossxthexplacentalxbarrier
c. psychoactive
d. highlyxlipid-soluble
Answer:xa
TextbookxReference:xPharmacokineticxFactorsxDeterminingxDrugxAction
15. Agentsxthatxinducexdevelopmentalxabnormalitiesxinxaxfetusxarexknownxas
a. psychoactivexdrugs.
b. illicitxdrugs.
c. teratogens.
d. placentalxdrugs.
Answer:xc
TextbookxReference:xPharmacokineticxFactorsxDeterminingxDrugxAction
16. Depotxbindingxisxsaidxtoxoccurxwhenxdrugs
a. bindxtoxtheirxtargetxsites.
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