VM 575 (Hepatology) EXAM 2 STUDY
REVISION QUESTIONS AND ANSWERS.
Which of the following is the most specific for decreased/abnormal liver
function:
A. Increased cholesterol
B. Decreased BUN
C. Increased bile acids
D. Increased bilirubin
C. Increased bile acids
Which statement is true about liver aspirates in dogs?
A. Cytology provides a definitive diagnosis in >50% of cases
B. Cytology is useful in diagnosing neoplastic disease
C. Cytology typically identifies inflammation in chronic hepatitis
D. Copper granules are routinely identified in dogs with increased hepatic
copper
B. Cytology is useful in diagnosing neoplastic disease
Approximately how many cases of clinical copper deficiency due to lack
of dietary copper were reported in dogs in the 1990s?
A. 0
B. 10
C. 100
D. >1000
A. 0
Which of the following is true when treating dogs with chronic hepatitis?
A. Aggressive immunosuppression with cyclosporine is needed in most
cases
B. Steroids are contraindicated because of increased risk for GI bleeding
C. Antioxidants alone are effective in >50% of cases
D. Antibiotics are needed to prevent secondary infections of diseased
,tissue
E. Treatments for chronic hepatitis are poorly studied
E. Treatments for chronic hepatitis are poorly studied
How long does it take to reduce copper levels into normal ranges?
A. <1 month
B. 1-2 months
C. 3-4 months
D. >4 months
E. >12 months
C. 3-4 months
You run a UA dipstick on a pig with icterus. Bilirubin is +++. What form of
bilirubin is being detected?
A. Urobilinogen
B. Unconjugated bilirubin
C. Conjugated bilirubin
C. Conjugated bilirubin
Select the most reasonable diagnostic plan for liver disease in a horse:
A. PE and biochemical evaluation for pathgnomonic signs
B. PE and biochemistry evaluation followed by ultrasound +/- biopsy
C. PE and biochemistry evaluation followed by +/- blind biopsy technique
D. PE and biochemistry evaluation followed by abdominal CT
B. PE and biochemistry evaluation followed by ultrasound +/- biopsy
What percentage of liver mass must be lost before liver function is
affected?
A. 30%
B. 50%
C. 70%
D. 90%
C. 70%
, Which zone is of the liver lobule is most susceptible to hypoxic/ischemic
injury?
A. Zone 1
B. Zone 2
C. Zone 3
C. Zone 3
How do we best investigate for post-hepatic causes of hyperbilirubinemia?
A. Abdominal radiograph
B. Abdominal ultrasound
C. Bile acids testing
D. Ammonia concentration
B. Abdominal ultrasound
Which is considered an important antidote to acetaminophen toxicosis in
cats?
A. Silymarin
B. N-acetylcysteine
C. Ursodiol
D. Amoxicillin
B. N-acetylcysteine
What medication has shown to be protective against hepatocellular
damage from Amanita mushrooms?
A. Silymarin
B. Ursodiol
C. Denamarin
D. Doxycycline
A. Silymarin
ALP and GGT are located _____ of the hepatocyte and are released into
the circulation when ________
A. along the canalicular membrane; hepatocytes are damaged
B. in the cytosol; hepatocytes are damaged
C. along the canalicular membrane; there is intrahepatic or extrahepatic
REVISION QUESTIONS AND ANSWERS.
Which of the following is the most specific for decreased/abnormal liver
function:
A. Increased cholesterol
B. Decreased BUN
C. Increased bile acids
D. Increased bilirubin
C. Increased bile acids
Which statement is true about liver aspirates in dogs?
A. Cytology provides a definitive diagnosis in >50% of cases
B. Cytology is useful in diagnosing neoplastic disease
C. Cytology typically identifies inflammation in chronic hepatitis
D. Copper granules are routinely identified in dogs with increased hepatic
copper
B. Cytology is useful in diagnosing neoplastic disease
Approximately how many cases of clinical copper deficiency due to lack
of dietary copper were reported in dogs in the 1990s?
A. 0
B. 10
C. 100
D. >1000
A. 0
Which of the following is true when treating dogs with chronic hepatitis?
A. Aggressive immunosuppression with cyclosporine is needed in most
cases
B. Steroids are contraindicated because of increased risk for GI bleeding
C. Antioxidants alone are effective in >50% of cases
D. Antibiotics are needed to prevent secondary infections of diseased
,tissue
E. Treatments for chronic hepatitis are poorly studied
E. Treatments for chronic hepatitis are poorly studied
How long does it take to reduce copper levels into normal ranges?
A. <1 month
B. 1-2 months
C. 3-4 months
D. >4 months
E. >12 months
C. 3-4 months
You run a UA dipstick on a pig with icterus. Bilirubin is +++. What form of
bilirubin is being detected?
A. Urobilinogen
B. Unconjugated bilirubin
C. Conjugated bilirubin
C. Conjugated bilirubin
Select the most reasonable diagnostic plan for liver disease in a horse:
A. PE and biochemical evaluation for pathgnomonic signs
B. PE and biochemistry evaluation followed by ultrasound +/- biopsy
C. PE and biochemistry evaluation followed by +/- blind biopsy technique
D. PE and biochemistry evaluation followed by abdominal CT
B. PE and biochemistry evaluation followed by ultrasound +/- biopsy
What percentage of liver mass must be lost before liver function is
affected?
A. 30%
B. 50%
C. 70%
D. 90%
C. 70%
, Which zone is of the liver lobule is most susceptible to hypoxic/ischemic
injury?
A. Zone 1
B. Zone 2
C. Zone 3
C. Zone 3
How do we best investigate for post-hepatic causes of hyperbilirubinemia?
A. Abdominal radiograph
B. Abdominal ultrasound
C. Bile acids testing
D. Ammonia concentration
B. Abdominal ultrasound
Which is considered an important antidote to acetaminophen toxicosis in
cats?
A. Silymarin
B. N-acetylcysteine
C. Ursodiol
D. Amoxicillin
B. N-acetylcysteine
What medication has shown to be protective against hepatocellular
damage from Amanita mushrooms?
A. Silymarin
B. Ursodiol
C. Denamarin
D. Doxycycline
A. Silymarin
ALP and GGT are located _____ of the hepatocyte and are released into
the circulation when ________
A. along the canalicular membrane; hepatocytes are damaged
B. in the cytosol; hepatocytes are damaged
C. along the canalicular membrane; there is intrahepatic or extrahepatic
