Basic .and .Clinical .Pharmacology .15th .Edition .
Katzung .Trevor .Test .Bank .Update .2025
.
TEST BANK .
, Page .2 .of .822
Basic .and .Clinical .Pharmacology .15th .Edition .Katzung .Trevor .Test . Bank
Chapter .1. .Introduction: .The .Nature .of .Drugs .& .Drug .Development .& .Regulation
1. A .nurse .working .in .radiology .administers .iodine .to .a .patient .who .is
.having .a .computed .tomography .(CT) .scan. .The .nurse .working .on .the
.oncology .unit .administers .chemotherapy .to .patients .who .have .cancer. .At
.the .Public .Health .Department, .a .nurse .administers .a .measles-mumps-
rubella .(MMR) .vaccine .to .a .14-month-old .child .as .a .routine .immunization.
.Which .branch .of .pharmacology .best .describes .the .actions .of .all .three
. nurses?
A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
Ans: B
Feedback:
Pharmacology .is .the .study .of .the .biologic .effects .of .chemicals. .Nurses .are
.involved .with .clinical .pharmacology .or .pharmacotherapeutics, .which .is .a
.branch .of .pharmacology .that .deals .with .the .uses .of .drugs .to .treat,
.prevent, .and .diagnose .disease. .The .radiology .nurse .is .administering .a
.drug .to .help .diagnose .a .disease. .The .oncology .nurse .is .administering .a
.drug .to .help .treat .a .disease. .Pharmacoeconomics .includes .any .costs
.involved .in .drug .therapy.
Pharmacodynamics .involves .how .a .drug .affects .the .body .and
.pharmacokinetics .is .how .the .body .acts .on .the .body.
2. When .involved .in .phase .III .drug .evaluation .studies, .what
.responsibilities .would .the .nurse .have?
A) Working .with .animals .who .are .given .experimental . drugs
B) Choosing .appropriate .patients .to .be .involved .in .the .drug . study
C) Monitoring .and .observing .patients .closely .for .adverse . effects
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D) Conducting .research .to .determine .effectiveness .of .the . drug
Ans: C
Feedback:
Phase .III .studies .involve .use .of .a .drug .in .a .vast .clinical .population .in
.which .patients .are .asked .to .record .any .symptoms .they .experience .while
.taking .the .drugs. .Nurses .may .be .responsible .for .helping .collect .and
.analyze .the .information .to .be .shared .with .the .Food .and .Drug
.Administration .(FDA) .but .would .not .conduct .research .independently
.because .nurses .do .not .prescribe .medications. .Use .of .animals .in .drug
.testing .is .done .in .the .preclinical .trials. .Select .patients .who .are .involved .in
.phase .II .studies .to .participate .in .studies .where .the .participants .have .the
.disease .the .drug .is .intended .to .treat. .These .patients .are .monitored .closely
.for .drug .action .and .adverse .effects. .Phase .I .studies .involve .healthy
.human .volunteers .who .are .usually .paid .for .their .participation. .Nurses
.may .observe .for .adverse .effects .and .toxicity.
3. A .physician .has .ordered .intramuscular .(IM) .injections .of .morphine, .a
.narcotic, .every .4 .hours .as .needed .for .pain .in .a .motor .vehicle .accident
.victim. .The .nurse .is .aware .this .drug .has .a .high .abuse .potential. .Under
.what .category .would .morphine .be .classified?
A) Schedule .I
B) Schedule .II
C) Schedule .III
D) Schedule .IV
Ans: B
Feedback:
Narcotics .with .a .high .abuse .potential .are .classified .as .Schedule .II .drugs
.because .of .severe .dependence .liability. .Schedule .I .drugs .have .high .abuse
.potential .and .no .accepted .medical .use. .Schedule .III .drugs .have .a .lesser
.abuse .potential .than .II .and .an .accepted .medical .use. .Schedule .IV .drugs
.have .low .abuse .potential .and .limited .dependence .liability.
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4. What .concept .is .considered .when .generic .drugs .are .substituted .for
.brand .name .drugs?
A) Bioavailability
B) Critical .concentration
C) Distribution
D) Half-life
Ans: A
Feedback:
Bioavailability .is .the .portion .of .a .dose .of .a .drug .that .reaches .the
.systemic .circulation .and .is .available .to .act .on .body .cells. .Binders .used .in
.a .generic .drug .may .not .be .the .same .as .those .used .in .the .brand .name
.drug. .Therefore, .the .way .the .body .breaks .down .and .uses .the .drug .may
.differ, .which .may .eliminate .a .generic .drug .substitution. .Critical
.concentration .is .the .amount .of .a .drug .that .is .needed .to .cause .a
.therapeutic .effect .and .should .not .differ .between .generic .and .brand .name
.medications. .Distribution .is .the .phase .of .pharmacokinetics, .which
.involves .the .movement .of .a .drug .to .the .bodys .tissues .and .is .the .same .in
.generic .and .brand .name .drugs. .A .drugs .half-life .is .the .time .it .takes .for
.the .amount .of .drug .to .decrease .to .half .the .peak .level, .which .should .not
.change .when .substituting .a .generic . medication.
5. A .nurse .is .assessing .the .patients .home .medication .use. .After .listening .to
.the .patient .list .current .medications, .the .nurse .asks .what .priority
.question?
A) Do .you .take .any .generic .medications?
B) Are .any .of .these .medications .orphan . drugs?
C) Are .these .medications .safe .to .take .during . pregnancy?
D) Do .you .take .any .over-the-counter . medications?
Ans: D
Feedback:
www.stuvia.com
Katzung .Trevor .Test .Bank .Update .2025
.
TEST BANK .
, Page .2 .of .822
Basic .and .Clinical .Pharmacology .15th .Edition .Katzung .Trevor .Test . Bank
Chapter .1. .Introduction: .The .Nature .of .Drugs .& .Drug .Development .& .Regulation
1. A .nurse .working .in .radiology .administers .iodine .to .a .patient .who .is
.having .a .computed .tomography .(CT) .scan. .The .nurse .working .on .the
.oncology .unit .administers .chemotherapy .to .patients .who .have .cancer. .At
.the .Public .Health .Department, .a .nurse .administers .a .measles-mumps-
rubella .(MMR) .vaccine .to .a .14-month-old .child .as .a .routine .immunization.
.Which .branch .of .pharmacology .best .describes .the .actions .of .all .three
. nurses?
A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
Ans: B
Feedback:
Pharmacology .is .the .study .of .the .biologic .effects .of .chemicals. .Nurses .are
.involved .with .clinical .pharmacology .or .pharmacotherapeutics, .which .is .a
.branch .of .pharmacology .that .deals .with .the .uses .of .drugs .to .treat,
.prevent, .and .diagnose .disease. .The .radiology .nurse .is .administering .a
.drug .to .help .diagnose .a .disease. .The .oncology .nurse .is .administering .a
.drug .to .help .treat .a .disease. .Pharmacoeconomics .includes .any .costs
.involved .in .drug .therapy.
Pharmacodynamics .involves .how .a .drug .affects .the .body .and
.pharmacokinetics .is .how .the .body .acts .on .the .body.
2. When .involved .in .phase .III .drug .evaluation .studies, .what
.responsibilities .would .the .nurse .have?
A) Working .with .animals .who .are .given .experimental . drugs
B) Choosing .appropriate .patients .to .be .involved .in .the .drug . study
C) Monitoring .and .observing .patients .closely .for .adverse . effects
www.stuvia.com
, Page .3 .of .822
D) Conducting .research .to .determine .effectiveness .of .the . drug
Ans: C
Feedback:
Phase .III .studies .involve .use .of .a .drug .in .a .vast .clinical .population .in
.which .patients .are .asked .to .record .any .symptoms .they .experience .while
.taking .the .drugs. .Nurses .may .be .responsible .for .helping .collect .and
.analyze .the .information .to .be .shared .with .the .Food .and .Drug
.Administration .(FDA) .but .would .not .conduct .research .independently
.because .nurses .do .not .prescribe .medications. .Use .of .animals .in .drug
.testing .is .done .in .the .preclinical .trials. .Select .patients .who .are .involved .in
.phase .II .studies .to .participate .in .studies .where .the .participants .have .the
.disease .the .drug .is .intended .to .treat. .These .patients .are .monitored .closely
.for .drug .action .and .adverse .effects. .Phase .I .studies .involve .healthy
.human .volunteers .who .are .usually .paid .for .their .participation. .Nurses
.may .observe .for .adverse .effects .and .toxicity.
3. A .physician .has .ordered .intramuscular .(IM) .injections .of .morphine, .a
.narcotic, .every .4 .hours .as .needed .for .pain .in .a .motor .vehicle .accident
.victim. .The .nurse .is .aware .this .drug .has .a .high .abuse .potential. .Under
.what .category .would .morphine .be .classified?
A) Schedule .I
B) Schedule .II
C) Schedule .III
D) Schedule .IV
Ans: B
Feedback:
Narcotics .with .a .high .abuse .potential .are .classified .as .Schedule .II .drugs
.because .of .severe .dependence .liability. .Schedule .I .drugs .have .high .abuse
.potential .and .no .accepted .medical .use. .Schedule .III .drugs .have .a .lesser
.abuse .potential .than .II .and .an .accepted .medical .use. .Schedule .IV .drugs
.have .low .abuse .potential .and .limited .dependence .liability.
www.stuvia.com
, Page .4 .of .822
4. What .concept .is .considered .when .generic .drugs .are .substituted .for
.brand .name .drugs?
A) Bioavailability
B) Critical .concentration
C) Distribution
D) Half-life
Ans: A
Feedback:
Bioavailability .is .the .portion .of .a .dose .of .a .drug .that .reaches .the
.systemic .circulation .and .is .available .to .act .on .body .cells. .Binders .used .in
.a .generic .drug .may .not .be .the .same .as .those .used .in .the .brand .name
.drug. .Therefore, .the .way .the .body .breaks .down .and .uses .the .drug .may
.differ, .which .may .eliminate .a .generic .drug .substitution. .Critical
.concentration .is .the .amount .of .a .drug .that .is .needed .to .cause .a
.therapeutic .effect .and .should .not .differ .between .generic .and .brand .name
.medications. .Distribution .is .the .phase .of .pharmacokinetics, .which
.involves .the .movement .of .a .drug .to .the .bodys .tissues .and .is .the .same .in
.generic .and .brand .name .drugs. .A .drugs .half-life .is .the .time .it .takes .for
.the .amount .of .drug .to .decrease .to .half .the .peak .level, .which .should .not
.change .when .substituting .a .generic . medication.
5. A .nurse .is .assessing .the .patients .home .medication .use. .After .listening .to
.the .patient .list .current .medications, .the .nurse .asks .what .priority
.question?
A) Do .you .take .any .generic .medications?
B) Are .any .of .these .medications .orphan . drugs?
C) Are .these .medications .safe .to .take .during . pregnancy?
D) Do .you .take .any .over-the-counter . medications?
Ans: D
Feedback:
www.stuvia.com
