PHCL 3100: Exam 1
Ca++, Na+ - ANS-Excitatory ions
K+, Cl- - ANS-Inhibitory ions
Glutamate - ANS-attention, memory (excitatory amino acid)
GABA - ANS-Sedation
Dopamine - ANS-Intensity, reward, alertness
Norepinephrine - ANS-alarm
Serotonin - ANS-emotion, sexual desire
Acetylcholine - ANS-attention, memory
Anandamide - ANS-cosmic "oneness," reward, appetite, analgesia
Adenosine - ANS-sleep-repair
histamine - ANS-emergency alert-vomit
Substance P - ANS-pain
Endorphines - ANS-"Pain? Meh!"
Neuropeptide Y - ANS-appetite
Cortistatin - ANS-Sleep
Hypocretin / Orexin - ANS-Wakefulness
Leptin - ANS-Appetite
Oxytocin - ANS-trust and love, social neediness
Vasopressin - ANS-emergency, blood pressure
Aspirin Naproxen - ANS-Alzheimer's drug
, NSAID
long term use beforehand may prevent AD
Lovastatin - ANS-Alzheimer's Drug
Prevents AD by reducing hypercholesterolemia
Antihypertensive Drugs - ANS-Alzheimer's Drug
Lowers high blood pressure preventing AD
Donepezil - ANS-Alzheimer's Drug
Inhibits AChE (metabolism)
Drug of choice for those not on other drugs
Rivastigmine - ANS-Alzheimer's Drug
Inhibits AChE (metabolism)
Drug of choice for those on multiple drugs
Memantine - ANS-Alzheimer's Drug
reversible NMDAr antagonist (decreases glutamate)
Sinemet - ANS-Parkinson Drug
Combination of L-Dopa and carbidopa
Entacapone - ANS-Parkinson Drug
COMT inhibitor
Used to extend sinemet duration of action
Trihexyphenidyl - ANS-Parkinson Drug
Anticholinergic
Anti SLUD effects
Bromocriptine - ANS-Parkinson Drug
Dopamine Receptor Agonist
Can cause fibrosis, dyskinesis, and hallucinations
Amantidine - ANS-Parkinson Drug
Enhances dopamine release
Antiviral
Selegiline - ANS-Parkinson Drug
Inhibits MAO increasing dopamine
Possibly neuroprotective
Apomorphine - ANS-Parkinson Drug
Ca++, Na+ - ANS-Excitatory ions
K+, Cl- - ANS-Inhibitory ions
Glutamate - ANS-attention, memory (excitatory amino acid)
GABA - ANS-Sedation
Dopamine - ANS-Intensity, reward, alertness
Norepinephrine - ANS-alarm
Serotonin - ANS-emotion, sexual desire
Acetylcholine - ANS-attention, memory
Anandamide - ANS-cosmic "oneness," reward, appetite, analgesia
Adenosine - ANS-sleep-repair
histamine - ANS-emergency alert-vomit
Substance P - ANS-pain
Endorphines - ANS-"Pain? Meh!"
Neuropeptide Y - ANS-appetite
Cortistatin - ANS-Sleep
Hypocretin / Orexin - ANS-Wakefulness
Leptin - ANS-Appetite
Oxytocin - ANS-trust and love, social neediness
Vasopressin - ANS-emergency, blood pressure
Aspirin Naproxen - ANS-Alzheimer's drug
, NSAID
long term use beforehand may prevent AD
Lovastatin - ANS-Alzheimer's Drug
Prevents AD by reducing hypercholesterolemia
Antihypertensive Drugs - ANS-Alzheimer's Drug
Lowers high blood pressure preventing AD
Donepezil - ANS-Alzheimer's Drug
Inhibits AChE (metabolism)
Drug of choice for those not on other drugs
Rivastigmine - ANS-Alzheimer's Drug
Inhibits AChE (metabolism)
Drug of choice for those on multiple drugs
Memantine - ANS-Alzheimer's Drug
reversible NMDAr antagonist (decreases glutamate)
Sinemet - ANS-Parkinson Drug
Combination of L-Dopa and carbidopa
Entacapone - ANS-Parkinson Drug
COMT inhibitor
Used to extend sinemet duration of action
Trihexyphenidyl - ANS-Parkinson Drug
Anticholinergic
Anti SLUD effects
Bromocriptine - ANS-Parkinson Drug
Dopamine Receptor Agonist
Can cause fibrosis, dyskinesis, and hallucinations
Amantidine - ANS-Parkinson Drug
Enhances dopamine release
Antiviral
Selegiline - ANS-Parkinson Drug
Inhibits MAO increasing dopamine
Possibly neuroprotective
Apomorphine - ANS-Parkinson Drug