Pharmacodynamics - Exam 2 Questions and Answers Latest Update 2025 Graded A+
Some asians lack the enzyme __________, causing an accumulation of __________. - Answers
acetaldehyde dehydrogenase, acetaldehyde
-dose of drug administered
-dose concentration
-drug concentration at site of action
-drug in tissues
-drug metabolized or excreted
THESE ALL REFER TO... - Answers pharmacokinetics
-pharmacologic effect
-clinical response
-toxicity
-efficacy
THESE ALL REFER TO... - Answers pharmacodynamics
It is the study of the biochemical and physiological effects of drugs on the body or on microorganisms or
parasites within or on the body and the mechanisms of drug action and the relationship between drug
concentration and effect.
What the drug does to the body OR How does a drug work?
What are 3 specific components of pharmacodynamics? - Answers 1. receptor binding
2. signal transduction
3. physiological effect
, What is a class of drug that does not follow the typical drug-target interaction? - Answers antacids--they
have no target
Do drugs create function? - Answers No, they alter existing functions
Drug Receptor - Answers Molecule on the surface or in the cell where drugs bind, producing an effect.
The bound drug is referred to as a ligand.
Most drug receptors are... - Answers proteins
Any substance that binds to another chemical entity (i.e. a receptor) to form a complex - Answers ligand
A molecule that binds to a receptor on a cell and triggers a reaction - Answers agonist
A molecule that interferes with the physiologic reaction of another - Answers antagonist
True or false--an agonist has the SAME effect as an endogenous ligand? - Answers true. These increase
ligand-receptor interactions, creating a cumulative effect
An ion channel is open when bound/unbound to ligand? - Answers bound
When a receptor is not functioning, even with more ligand, it is said to be... - Answers desensitized
True or false: most drugs have multiple effects - Answers T
What are the 4 main steps of signal transduction? - Answers 1. signal
2. signal detection
3. signal transduction
4. response to signal
While most drug receptors are proteins, they can also be... - Answers nucleic enzymes or lipids
What are some examples of drug receptors that are proteins? - Answers - G-protein coupled receptors
- Receptors that function as enzymes
- Nuclear or intracellular receptors
- Ligand-gated ion channels
- Transporters
- Enzymes
What are the 4 main categories of receptor families? - Answers 1. ligand gated ion channels
2. G-protein coupled receptors
Some asians lack the enzyme __________, causing an accumulation of __________. - Answers
acetaldehyde dehydrogenase, acetaldehyde
-dose of drug administered
-dose concentration
-drug concentration at site of action
-drug in tissues
-drug metabolized or excreted
THESE ALL REFER TO... - Answers pharmacokinetics
-pharmacologic effect
-clinical response
-toxicity
-efficacy
THESE ALL REFER TO... - Answers pharmacodynamics
It is the study of the biochemical and physiological effects of drugs on the body or on microorganisms or
parasites within or on the body and the mechanisms of drug action and the relationship between drug
concentration and effect.
What the drug does to the body OR How does a drug work?
What are 3 specific components of pharmacodynamics? - Answers 1. receptor binding
2. signal transduction
3. physiological effect
, What is a class of drug that does not follow the typical drug-target interaction? - Answers antacids--they
have no target
Do drugs create function? - Answers No, they alter existing functions
Drug Receptor - Answers Molecule on the surface or in the cell where drugs bind, producing an effect.
The bound drug is referred to as a ligand.
Most drug receptors are... - Answers proteins
Any substance that binds to another chemical entity (i.e. a receptor) to form a complex - Answers ligand
A molecule that binds to a receptor on a cell and triggers a reaction - Answers agonist
A molecule that interferes with the physiologic reaction of another - Answers antagonist
True or false--an agonist has the SAME effect as an endogenous ligand? - Answers true. These increase
ligand-receptor interactions, creating a cumulative effect
An ion channel is open when bound/unbound to ligand? - Answers bound
When a receptor is not functioning, even with more ligand, it is said to be... - Answers desensitized
True or false: most drugs have multiple effects - Answers T
What are the 4 main steps of signal transduction? - Answers 1. signal
2. signal detection
3. signal transduction
4. response to signal
While most drug receptors are proteins, they can also be... - Answers nucleic enzymes or lipids
What are some examples of drug receptors that are proteins? - Answers - G-protein coupled receptors
- Receptors that function as enzymes
- Nuclear or intracellular receptors
- Ligand-gated ion channels
- Transporters
- Enzymes
What are the 4 main categories of receptor families? - Answers 1. ligand gated ion channels
2. G-protein coupled receptors
