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two types of inflammation
acute and chronic
acute inflammation
The immediate response to injury of local tissues; The body responds by attempting to
remove the offending agent to limit the amount of damage to the tissues affected
three stages of acute inflammation
Vascular Stage; Cellular Stage; Opsonization
vascular stage
changes occur in the small blood vessels at the site of the cellular and tissue injury
vasoconstriction is followed by vasodilation of the capillaries to increase capillary blood
flow, increasing temperatures and redness at the site
protein exudate increases causing swelling, pain, and diminished functional mobility
cellular stage
influx of leukocytes, primarily neutrophils
opsonization
facilitates phagocytosis
clinical manifestations in acute inflammation
, pain, redness, and swelling
if there are breaks in the integumentary system, there may be
drainage of exudate
in the event of a viral or bacterial infection associated with inflammation, there
may be
fever and general malaise
chronic inflammation
Occurs over longer periods, even years; May occur in response to acute inflammation
Clinical Manifestation in chronic inflammation
Tissue destruction and scarring may develop, the development of scarring replaces the
connective of parenchymal tissue, resulting in diminished mobility or function
Infections occur when microorganisms
invade a host; attach to host cell receptors; multiply in sufficient numbers to cause injury
Infection stimulates the body's immune response
In many instances, this immune response is sufficient to contain an infection
Antimicrobial Medications
Used to treat or prevent infections; Are necessary when host defense mechanisms are
inadequate to ward off infection
Microorganisms attach to host cell receptors
Invade tissues; Multiply; Produce infection
______ protect microbes from host defense mechanisms and antimicrobials
Biological adaptations
Most microorganisms have characteristics that allow them to adapt to