MPAT UNIT - VI Thermal Techniques: a) Thermogravimetric analysis (TGA), differential thermal analysis,

UNIT - VI Thermal Techniques: a) Thermogravimetric analysis (TGA): Principle, instrumentation, factors affecting results, advantage and disadvantages, pharmaceutical applications. b) Differential scanning calorimetry (DSC): Principle, thermal transitions and Instrumentation (Heat flux and power-compensation and designs), Modulated DSC, Hyper DSC, experimental parameters (sample preparation, experimental conditions, calibration, heating and cooling rates, resolution, source of errors) and their influence, advantage and disadvantages, pharmaceutical applications. 08 hrs c) Differential Thermal Analysis (DTA): Principle, instrumentation and advantage and disadvantages, pharmaceutical applications, derivative differential thermal analysis (DDTA).