BMTCN Chapter 6
Which of the following is NOT an identified risk factor associated with infection?
A. Personal history of infection
B. Type of transplantation (autologous or allogeneic)
C. Myeloablative transplant
D. None of the above correct answerD. None of the above
Clostridium difficile is not a common infection in the post-transplant setting.
A. True
B. False correct answerB. False
A cord blood transplantation is associated with all of the following EXCEPT:
A. Prolonged neutrophil and immune recovery
B. Increase in viral infections
C. Decrease in bacterial infections
D. Decrease in graft-versus-host disease (GVHD) correct answerC. Decrease in bacterial infections
Which of the following is true when considering bacterial infections in patients after transplant?
A. Patients are at a significant risk for encapsulated bacterial infections.
B. Multidrug-resistant organisms are not a major concern.
C. Streptococcus pneumoniae is not a common post-transplant bacterial infection.
D. Immunizations are not effective in controlling post-transplant bacterial or viral infections. correct
answerA. Patients are at a significant risk for encapsulated bacterial infections.
,The following strategies should be considered in an effort to prevent post-transplant infectious
complications.
(1) Immunizations should begin immediately following transplant discharge.
(2) Antiviral and anti-fungal prophylaxis medications should be considered in the post-transplant setting.
(3) Lifestyle restrictions vary in each transplant center and often are enforced to decrease post-
transplant infections. It is important to communicate lifestyle expectations and restrictions to patients
and their families.
(4) Measles, mumps, and rubella immunization should be administered at 12 months.
A. 1,2,3,4
B. 2 and 3
C. 2 and 4
D. 2,3,4 correct answerB. 2 and 3
Cardiovascular disease may be underreported in hematopoietic stem cell transplant (HSCT) recipients
because symptoms may occur several months to several years following HSCT.
A. True
B. False correct answerA. True
Which risk factors are associated with post-HSCT cardiovascular disease?
(1) Hypertension, (2) Gender, (3) Certain immunosuppressive medications, (4) Previous anthracycline
chemotherapy
A. 1,2,3,4
B. 1,3,4
C. 2,3,4
D. 1,2,3 correct answerB. 1,3,4
, The following strategies are used to manage cardiovascular disease in post-HSCT patients EXCEPT:
A. Antihypertensive medications
B. Statin therapy
C. Dietary counseling
D. Prophylactic anti-fungal medications correct answerD. Prophylactic anti-fungal medications
Patients should be monitored for the clinical signs and symptoms of cardiac disease post- HSCT by which
of the following?
A. Annual clinical assessment that includes baseline vital signs, review of symptoms, and physical
examination
B. Careful attention to travel over the last year
C. Lifestyle counseling about smoking cessation, weight management, and stress reduction
D. All of the above except B
E. All of the above except C correct answerD. All of the above except B
Which of the following chemotherapy agents is associated with patients with cardiac disease in the post-
HSCT setting?
A. Bendamustine
B. Melphalan
C. Doxorubicin
D. Methotrexate correct answerC. Doxorubicin
Graft failure or graft rejection is associated with all of the following EXCEPT:
A. Incidence of 1%-20%
B. Favorable prognosis
C. Loss of donor cells after initial engraftment
D. Potential for marrow aplasia and pancytopenia correct answerB. Favorable prognosis
Which of the following is NOT an identified risk factor associated with infection?
A. Personal history of infection
B. Type of transplantation (autologous or allogeneic)
C. Myeloablative transplant
D. None of the above correct answerD. None of the above
Clostridium difficile is not a common infection in the post-transplant setting.
A. True
B. False correct answerB. False
A cord blood transplantation is associated with all of the following EXCEPT:
A. Prolonged neutrophil and immune recovery
B. Increase in viral infections
C. Decrease in bacterial infections
D. Decrease in graft-versus-host disease (GVHD) correct answerC. Decrease in bacterial infections
Which of the following is true when considering bacterial infections in patients after transplant?
A. Patients are at a significant risk for encapsulated bacterial infections.
B. Multidrug-resistant organisms are not a major concern.
C. Streptococcus pneumoniae is not a common post-transplant bacterial infection.
D. Immunizations are not effective in controlling post-transplant bacterial or viral infections. correct
answerA. Patients are at a significant risk for encapsulated bacterial infections.
,The following strategies should be considered in an effort to prevent post-transplant infectious
complications.
(1) Immunizations should begin immediately following transplant discharge.
(2) Antiviral and anti-fungal prophylaxis medications should be considered in the post-transplant setting.
(3) Lifestyle restrictions vary in each transplant center and often are enforced to decrease post-
transplant infections. It is important to communicate lifestyle expectations and restrictions to patients
and their families.
(4) Measles, mumps, and rubella immunization should be administered at 12 months.
A. 1,2,3,4
B. 2 and 3
C. 2 and 4
D. 2,3,4 correct answerB. 2 and 3
Cardiovascular disease may be underreported in hematopoietic stem cell transplant (HSCT) recipients
because symptoms may occur several months to several years following HSCT.
A. True
B. False correct answerA. True
Which risk factors are associated with post-HSCT cardiovascular disease?
(1) Hypertension, (2) Gender, (3) Certain immunosuppressive medications, (4) Previous anthracycline
chemotherapy
A. 1,2,3,4
B. 1,3,4
C. 2,3,4
D. 1,2,3 correct answerB. 1,3,4
, The following strategies are used to manage cardiovascular disease in post-HSCT patients EXCEPT:
A. Antihypertensive medications
B. Statin therapy
C. Dietary counseling
D. Prophylactic anti-fungal medications correct answerD. Prophylactic anti-fungal medications
Patients should be monitored for the clinical signs and symptoms of cardiac disease post- HSCT by which
of the following?
A. Annual clinical assessment that includes baseline vital signs, review of symptoms, and physical
examination
B. Careful attention to travel over the last year
C. Lifestyle counseling about smoking cessation, weight management, and stress reduction
D. All of the above except B
E. All of the above except C correct answerD. All of the above except B
Which of the following chemotherapy agents is associated with patients with cardiac disease in the post-
HSCT setting?
A. Bendamustine
B. Melphalan
C. Doxorubicin
D. Methotrexate correct answerC. Doxorubicin
Graft failure or graft rejection is associated with all of the following EXCEPT:
A. Incidence of 1%-20%
B. Favorable prognosis
C. Loss of donor cells after initial engraftment
D. Potential for marrow aplasia and pancytopenia correct answerB. Favorable prognosis
