NURS 60441 PHARMACOTHERAPEUTICS FOR ADVANCED PRACTICE
n n n n n n
NURSE PRESCRIBERS, 5TH EDITION TEST BANK FINAL EXAM QUEST
n n n n n n n n
IONS AND ANSWERS BEST RATED A+ GUARANTEED SUCCESS LATES
n n n n n n n n
T UPDATE 2022
n n
Chapter 18. Drugs Affecting the Endocrine System: Pancreatic Hormones and Antidiabetic
n n n n n n n n n n n
Drugs
Patients with cystic fibrosis are often prescribed enzyme replacement for pancreatic secr
n n n n n n n n n n n
etions. Each replacement drug has lipase, protease, and amylase components, but the dru
n n n n n n n n n n n n
g is prescribed in units of:
n n n n n
a. Lipase
b. Protease
c. Amylase
d. Pancreatin
Brands of pancreatic enzyme replacement drugs are:
n n n n n n
a. Bioequivalent
b. About the same in cost per unit of lipase across brands
n n n n n n n n n n
c. Able to be interchanged between generic and brand-name products to reduce cost
n n n n n n n n n n n
d. None of the above n n n
When given subcutaneously, how long until neutral protamine Hagedorn insulin begins to tak
n n n n n n n n n n n n
e effect (onsetof action) after administration?
n n n n n n
a. 15 to 30 minutes n n n
b. 60 to 90 minutes n n n
c. 3 to 4 hours n n n
d. 6 to 8 hours n n n
Hypoglycemia can result from the action of either insulin or an oral hypoglycemic. Signs and
n n n n n n n n n n n n n n n
NURS 60441 PHARMACOTHERAPEUTICS FOR ADVANCED PRACTICE
n n n n n n
NURSE PRESCRIBERS, 5TH EDITION TEST BANK FINAL EXAM QUEST
n n n n n n n n
IONS AND ANSWERS BEST RATED A+ GUARANTEED SUCCESS LATES
n n n n n n n n
T UPDATE 2022
n n
,NURS 60441 PHARMACOTHERAPEUTICS FOR ADVANCED PRACTICE
n n n n n n
NURSE PRESCRIBERS, 5TH EDITION TEST BANK FINAL EXAM QUEST
n n n n n n n n
IONS AND ANSWERS BEST RATED A+ GUARANTEED SUCCESS LATES
n n n n n n n n
T UPDATE 2022
n n
symptoms ofhypoglycemia include: n n n
a. “Fruity” breath odor and rapid respiration n n n n n
b. Diarrhea, abdominal pain, weight loss, and hyper n n n n n n
tensionc. Dizziness, confusion, diaphoresis, and tac
n n n n n n
hycardia
d. Easy bruising, palpitations, cardiac dysrhythmias, and coma
n n n n n n n
Nonselective beta blockers and alcohol create serious drug interactions with insulin because they:
n n n n n n n n n n n n
a. Increase blood glucose levels n n n
b. Produce unexplained diaphoresis n n
c. Interfere with the ability of the body to metabolize n n n n n n n n n
glucosed. Mask the signs and symptoms of altered gluc
n n n n n n n n n
ose levels n
Lispro is an insulin analogue produced by recombinant DNA technology. W
n n n n n n n n n n
hich of thefollowing statements about this form of insulin is NOT true?
n n n n n n n n n n n n
a. Optimal time of preprandial injection is 15 minutes. n n n n n n n
b. Duration of action is increased when the dose is increased. n n n n n n n n n
c. It is compatible with neutral protamine Hagedorn insulin.
n n n n n n n
d. It has no pronounced peak.
n n n n
The decision may be made to switch from twice daily neutral protamine Haged
n n n n n n n n n n n n
orn (NPH)insulin to insulin glargine to improve glycemia control throughout t
n n n n n n n n n n n
he day. If this is done:
n n n n n
NURS 60441 PHARMACOTHERAPEUTICS FOR ADVANCED PRACTICE
n n n n n n
NURSE PRESCRIBERS, 5TH EDITION TEST BANK FINAL EXAM QUEST
n n n n n n n n
IONS AND ANSWERS BEST RATED A+ GUARANTEED SUCCESS LATES
n n n n n n n n
T UPDATE 2022
n n
,NURS 60441 PHARMACOTHERAPEUTICS FOR ADVANCED PRACTICE
n n n n n n
NURSE PRESCRIBERS, 5TH EDITION TEST BANK FINAL EXAM QUEST
n n n n n n n n
IONS AND ANSWERS BEST RATED A+ GUARANTEED SUCCESS LATES
n n n n n n n n
T UPDATE 2022
n n
a. The initial dose of glargine is reduced by 20% to avoid hypoglycemia.
n n n n n n n n n n n
b. The initial dose of glargine is 2 to 10 units per day.
n n n n n n n n n n n
c. Patients who have been on high doses of NPH will need tests for insulin antibodies.
n n n n n n n n n n n n n n
d. Obese patients may require more than 100 units per day.
n n n n n n n n n
When blood glucose levels are difficult to control in type 2 diabetes some form of i
n n n n n n n n n n n n n n n
nsulin maybe added to the treatment regimen to control blood glucose and limit co
n n n n n n n n n n n n n n
mplication risks. n
Which ofthe following statements is accurate based on research?
n n n n n n n n
a. Premixed insulin analogues are better at lowering HbA1C and have le
n n n n n n n n n n
ss risk forhypoglycemia.
n n n
b. Premixed insulin analogues and the newer premixed insulins are associated
n n n n n n n n n n
with moreweight gain than the oral antidiabetic agents.
n n n n n n n n
c. Newer premixed insulins are better at lowering HbA1C and postprandi
n n n n n n n n n
al glucoselevels than long-acting insulins.
n n n n n
d. Patients who are not controlled on oral agents and have postprandial hype
n n n n n n n n n n n
rglycemiacan have neutral protamine Hagedorn insulin added at bedtime.
n n n n n n n n n
Metformin is a primary choice of drug to treat hyperglycemia in type 2 diabetes because it:
n n n n n n n n n n n n n n n
a. Substitutes for insulin usually secreted by the p n n n n n n n
ancreasb. Decreases glycogenolysis by the liver
n n n n n n
c. Increasesnthenreleasenofninsulinnfromnbetancells
d. Decreasesnperipheralnglucosenutilization
Prior to prescribing metformin, the provider should:
n n n n n n
NURS 60441 PHARMACOTHERAPEUTICS FOR ADVANCED PRACTICE
n n n n n n
NURSE PRESCRIBERS, 5TH EDITION TEST BANK FINAL EXAM QUEST
n n n n n n n n
IONS AND ANSWERS BEST RATED A+ GUARANTEED SUCCESS LATES
n n n n n n n n
T UPDATE 2022
n n
, NURS 60441 PHARMACOTHERAPEUTICS FOR ADVANCED PRACTICE
n n n n n n
NURSE PRESCRIBERS, 5TH EDITION TEST BANK FINAL EXAM QUEST
n n n n n n n n
IONS AND ANSWERS BEST RATED A+ GUARANTEED SUCCESS LATES
n n n n n n n n
T UPDATE 2022 n n
a. Draw a serum creatinine to assess renal function
n n n n n n n
b. Try the patient on insulin
n n n n
c. Tell the patient to increase iodine intake
n n n n n n
d. Have the patient stop taking any sulfonylurea to avoid dangerous drug interactions
n n n n n n n n n n n
The action of “gliptins” is different from other antidiabetic agents because they:
n n n n n n n n n n n
a. Have a low risk for hypoglycemia
n n n n n
b. Are not associated with weight gain
n n n n n
c. Close ATP-dependent potassium channels in the beta cell
n n n n n n n
d. Act on the incretin system to indirectly increase insulin production
n n n n n n n n n
Sitagliptin has been approved for:
n n n n
a. Monotherapy in once-daily doses n n n
b. Combination therapy with metformin n n n
c. Both 1 and 2
n n n n
d. Neither 1 nor 2 n n n
GLP-1 agonists: n
a. Directly bind to a receptor in the pancreatic beta cell
n n n n n n n n n
b. Have been approved for monotherapy
n n n n
c. Speed gastric emptying to decrease appetite
n n n n n
d. Can be given orally once daily
n n n n n
Avoid concurrent administration of exenatide with which of the following drugs?
n n n n n n n n n n
a. Digoxin
NURS 60441 PHARMACOTHERAPEUTICS FOR ADVANCED PRACTICE
n n n n n n
NURSE PRESCRIBERS, 5TH EDITION TEST BANK FINAL EXAM QUEST
n n n n n n n n
IONS AND ANSWERS BEST RATED A+ GUARANTEED SUCCESS LATES
n n n n n n n n
T UPDATE 2022 n n
n n n n n n
NURSE PRESCRIBERS, 5TH EDITION TEST BANK FINAL EXAM QUEST
n n n n n n n n
IONS AND ANSWERS BEST RATED A+ GUARANTEED SUCCESS LATES
n n n n n n n n
T UPDATE 2022
n n
Chapter 18. Drugs Affecting the Endocrine System: Pancreatic Hormones and Antidiabetic
n n n n n n n n n n n
Drugs
Patients with cystic fibrosis are often prescribed enzyme replacement for pancreatic secr
n n n n n n n n n n n
etions. Each replacement drug has lipase, protease, and amylase components, but the dru
n n n n n n n n n n n n
g is prescribed in units of:
n n n n n
a. Lipase
b. Protease
c. Amylase
d. Pancreatin
Brands of pancreatic enzyme replacement drugs are:
n n n n n n
a. Bioequivalent
b. About the same in cost per unit of lipase across brands
n n n n n n n n n n
c. Able to be interchanged between generic and brand-name products to reduce cost
n n n n n n n n n n n
d. None of the above n n n
When given subcutaneously, how long until neutral protamine Hagedorn insulin begins to tak
n n n n n n n n n n n n
e effect (onsetof action) after administration?
n n n n n n
a. 15 to 30 minutes n n n
b. 60 to 90 minutes n n n
c. 3 to 4 hours n n n
d. 6 to 8 hours n n n
Hypoglycemia can result from the action of either insulin or an oral hypoglycemic. Signs and
n n n n n n n n n n n n n n n
NURS 60441 PHARMACOTHERAPEUTICS FOR ADVANCED PRACTICE
n n n n n n
NURSE PRESCRIBERS, 5TH EDITION TEST BANK FINAL EXAM QUEST
n n n n n n n n
IONS AND ANSWERS BEST RATED A+ GUARANTEED SUCCESS LATES
n n n n n n n n
T UPDATE 2022
n n
,NURS 60441 PHARMACOTHERAPEUTICS FOR ADVANCED PRACTICE
n n n n n n
NURSE PRESCRIBERS, 5TH EDITION TEST BANK FINAL EXAM QUEST
n n n n n n n n
IONS AND ANSWERS BEST RATED A+ GUARANTEED SUCCESS LATES
n n n n n n n n
T UPDATE 2022
n n
symptoms ofhypoglycemia include: n n n
a. “Fruity” breath odor and rapid respiration n n n n n
b. Diarrhea, abdominal pain, weight loss, and hyper n n n n n n
tensionc. Dizziness, confusion, diaphoresis, and tac
n n n n n n
hycardia
d. Easy bruising, palpitations, cardiac dysrhythmias, and coma
n n n n n n n
Nonselective beta blockers and alcohol create serious drug interactions with insulin because they:
n n n n n n n n n n n n
a. Increase blood glucose levels n n n
b. Produce unexplained diaphoresis n n
c. Interfere with the ability of the body to metabolize n n n n n n n n n
glucosed. Mask the signs and symptoms of altered gluc
n n n n n n n n n
ose levels n
Lispro is an insulin analogue produced by recombinant DNA technology. W
n n n n n n n n n n
hich of thefollowing statements about this form of insulin is NOT true?
n n n n n n n n n n n n
a. Optimal time of preprandial injection is 15 minutes. n n n n n n n
b. Duration of action is increased when the dose is increased. n n n n n n n n n
c. It is compatible with neutral protamine Hagedorn insulin.
n n n n n n n
d. It has no pronounced peak.
n n n n
The decision may be made to switch from twice daily neutral protamine Haged
n n n n n n n n n n n n
orn (NPH)insulin to insulin glargine to improve glycemia control throughout t
n n n n n n n n n n n
he day. If this is done:
n n n n n
NURS 60441 PHARMACOTHERAPEUTICS FOR ADVANCED PRACTICE
n n n n n n
NURSE PRESCRIBERS, 5TH EDITION TEST BANK FINAL EXAM QUEST
n n n n n n n n
IONS AND ANSWERS BEST RATED A+ GUARANTEED SUCCESS LATES
n n n n n n n n
T UPDATE 2022
n n
,NURS 60441 PHARMACOTHERAPEUTICS FOR ADVANCED PRACTICE
n n n n n n
NURSE PRESCRIBERS, 5TH EDITION TEST BANK FINAL EXAM QUEST
n n n n n n n n
IONS AND ANSWERS BEST RATED A+ GUARANTEED SUCCESS LATES
n n n n n n n n
T UPDATE 2022
n n
a. The initial dose of glargine is reduced by 20% to avoid hypoglycemia.
n n n n n n n n n n n
b. The initial dose of glargine is 2 to 10 units per day.
n n n n n n n n n n n
c. Patients who have been on high doses of NPH will need tests for insulin antibodies.
n n n n n n n n n n n n n n
d. Obese patients may require more than 100 units per day.
n n n n n n n n n
When blood glucose levels are difficult to control in type 2 diabetes some form of i
n n n n n n n n n n n n n n n
nsulin maybe added to the treatment regimen to control blood glucose and limit co
n n n n n n n n n n n n n n
mplication risks. n
Which ofthe following statements is accurate based on research?
n n n n n n n n
a. Premixed insulin analogues are better at lowering HbA1C and have le
n n n n n n n n n n
ss risk forhypoglycemia.
n n n
b. Premixed insulin analogues and the newer premixed insulins are associated
n n n n n n n n n n
with moreweight gain than the oral antidiabetic agents.
n n n n n n n n
c. Newer premixed insulins are better at lowering HbA1C and postprandi
n n n n n n n n n
al glucoselevels than long-acting insulins.
n n n n n
d. Patients who are not controlled on oral agents and have postprandial hype
n n n n n n n n n n n
rglycemiacan have neutral protamine Hagedorn insulin added at bedtime.
n n n n n n n n n
Metformin is a primary choice of drug to treat hyperglycemia in type 2 diabetes because it:
n n n n n n n n n n n n n n n
a. Substitutes for insulin usually secreted by the p n n n n n n n
ancreasb. Decreases glycogenolysis by the liver
n n n n n n
c. Increasesnthenreleasenofninsulinnfromnbetancells
d. Decreasesnperipheralnglucosenutilization
Prior to prescribing metformin, the provider should:
n n n n n n
NURS 60441 PHARMACOTHERAPEUTICS FOR ADVANCED PRACTICE
n n n n n n
NURSE PRESCRIBERS, 5TH EDITION TEST BANK FINAL EXAM QUEST
n n n n n n n n
IONS AND ANSWERS BEST RATED A+ GUARANTEED SUCCESS LATES
n n n n n n n n
T UPDATE 2022
n n
, NURS 60441 PHARMACOTHERAPEUTICS FOR ADVANCED PRACTICE
n n n n n n
NURSE PRESCRIBERS, 5TH EDITION TEST BANK FINAL EXAM QUEST
n n n n n n n n
IONS AND ANSWERS BEST RATED A+ GUARANTEED SUCCESS LATES
n n n n n n n n
T UPDATE 2022 n n
a. Draw a serum creatinine to assess renal function
n n n n n n n
b. Try the patient on insulin
n n n n
c. Tell the patient to increase iodine intake
n n n n n n
d. Have the patient stop taking any sulfonylurea to avoid dangerous drug interactions
n n n n n n n n n n n
The action of “gliptins” is different from other antidiabetic agents because they:
n n n n n n n n n n n
a. Have a low risk for hypoglycemia
n n n n n
b. Are not associated with weight gain
n n n n n
c. Close ATP-dependent potassium channels in the beta cell
n n n n n n n
d. Act on the incretin system to indirectly increase insulin production
n n n n n n n n n
Sitagliptin has been approved for:
n n n n
a. Monotherapy in once-daily doses n n n
b. Combination therapy with metformin n n n
c. Both 1 and 2
n n n n
d. Neither 1 nor 2 n n n
GLP-1 agonists: n
a. Directly bind to a receptor in the pancreatic beta cell
n n n n n n n n n
b. Have been approved for monotherapy
n n n n
c. Speed gastric emptying to decrease appetite
n n n n n
d. Can be given orally once daily
n n n n n
Avoid concurrent administration of exenatide with which of the following drugs?
n n n n n n n n n n
a. Digoxin
NURS 60441 PHARMACOTHERAPEUTICS FOR ADVANCED PRACTICE
n n n n n n
NURSE PRESCRIBERS, 5TH EDITION TEST BANK FINAL EXAM QUEST
n n n n n n n n
IONS AND ANSWERS BEST RATED A+ GUARANTEED SUCCESS LATES
n n n n n n n n
T UPDATE 2022 n n
