NAVLE
5-fluorouracil - ANS - cats = NEUROTOXIC
ER
Acetaminophen toxicity - ANS - toxic to CATS and ferrets
H
- cats lack glutathione and glucoronyl transferase --> heinz body hemolytic
IG
anemia + liver damage + methemoglobinemia
H
- facial and paw edema = allergic/hypersensitivity
G
- tx = emesis/gastric lavage within 4-6 hrs, N-acetylcysteine
N
I
- monitor methemoglobin (>50% grave)
LY
Acquired myasthenia gravis - ANS - signs = episodic weakness, pelvic
F
weakness, regurgitation, depressed palpebral reflex, no CP deficits
- dfdx = myopathy, tick paralysis, neuropathy, systemic illness, organophosphate,
hypoT, botulism, thymoma
- dx = ACh receptor antibody test, thoracic rads, tensilon
, 2
- tx = aspiration pneumonia, elevated feeding, anticholinesterase
(pyridostigmine), steroids
R
Aelurostrongylus abstrusus - ANS - cat lungworm
- dx = baermann
HE
G
- tx = fenben
Afib - ANS
HI
- most common supraventricular arrhythmia in cattle = digestive
G
disturbance or electrolyte abnormality associated w/ vagal tone, hypokalemia,
hyperkalemia, calcium therapy, myocardial irritation
IN
- most common pathologic arrhythmia in horses = poor performance, exercise
Y
intolerance, may appear normal
FL
- pulsus alternans = 2 quick normal pulses in row followed by no pulse
- tx horses = quinidine, digoxin
- tx dogs = diltiazem, atenolol, digoxin, procainamide
, 3
Aflatoxin - ANS - mycotoxin (from aspergillus)
- icertus, hemorrhage, sudden death
R
- similar lesions to PAs
HE
- subacute hepatic necrosis and fibrosis
G
- found in moldy grains
Amitraz - ANS
HI
- sedation, stimulation of alpha 2 receptors
G
- reverse w/ atipamazole
IN
Anaplasma marginale - ANS - tick dz of cows
LY
- signs = EXTRAVASCULAR HEMOLYSIS, NO hemoglobinuria, late term abortion
F
- see in new additions to herd = weak, depressed, staring into space, pale, icteric,
febrile
Anthrax - ANS - horses and cows = sudden death, colic, fever, SQ edema
, 4
- dead animals do not show signs of rigor mortis w/ unclotted blood exuding
- DO NOT NECROPSY
R
- dx = vitreous humor
- zoonotic
HE
G
Aortic thromboembolism - ANS - middle age male > female
HI
- signs = acute onset pain, paraplegia, COOL CYANOTIC FEET/NAIL BEDS, loss of
G
deep pain
N
- dfdx = spinal trauma, spinal tumor, myelitis, pelvic fracture
YI
- dx = bloodwork, heartworm, T4, coag, echo, doppler, FAST scan
FL
- tx = tx underlying dz and manage pain, close dissolution (warfarin heparin),
clopidogrel
APCs - ANS - causes pulse deficits
- supra-ventricular tachycardia/ventricular tachycardia OR intermittent