Current Diagnosis & Treatment Obstetrics &
Gynecology 2025 12th Edition questions and answers
2025
Female have regular cycle every 30 days her last period before 36, she received
rubella vaccine before 3 weeks. She was asked not to get pregnant until 2 months
of receiving rubella , But she got pregnant, what’s the most likely pregnancy
outcome?
A. Not affected
B. Associated with congenital malformations.
Correct Answer: A
Explanation: (According to Williams Obstetrics and UpToDate)
- Inadvertent administration of measles, mumps, rubella (MMR) or varicella
vaccines during pregnancy should not generally be considered indications
for pregnancy termination.
- ACIP and American College of Obstetricians and Gynecologists (ACOG)
recommendations to avoid pregnancy for one month following each dose of
a live vaccine. Nevertheless, adverse outcomes in women who became
pregnant soon after receiving these vaccines have not been established
Pregnant women doesnt have rubella vaccine what should do?
A. Take in second trimester.
B. Postpartum
Correct Answer: B
Explanation: (According to UpToDate)
POSTPARTUM IMMUNIZATION
- MMR and varicella – The following vaccines should be given before discharge
to protect a nonimmune mother and newborn:
o MMR – The measles, mumps, rubella (MMR) vaccine should be
administered to women nonimmune to rubella or measles
o Varicella vaccination is recommended for women without evidence of
immunity. The first dose is given while the patient is in the hospital and
the second dose is given four to eight weeks later, which typically
coincides with the routine postpartum visit. Breastfeeding is not a
contraindication to administration.
1|Page
,Obstetrics and Gynecology: SMLE Questions and Answers Chapter 1: Obstetrics
Pregnant her child school had an outbreak and she’s afraid to get to her child
which vaccine she should get ?
A. DtaP
B. Influenza
C. Rubella
D. Varicella
Correct Answer: B
Explanation: (According to UpToDate)
Inactivated Influenza Vaccine
- All women who are pregnant or might be pregnant during the influenza
season should receive the inactivated influenza vaccine as soon as it
becomes available and before onset of influenza activity in the community,
regardless of their stage of pregnancy
A woman was taking highly androgenic progesterone without knowing she is
pregnant. What complication will her daughter face?
A. Nothing will change
B. Hirsutism
C. Masculinization
D. Feminization
2|Page
,Current Diagnosis & Treatment Obstetrics &
Gynecology 2025 12th Edition questions and answers
2025
Correct Answer: C
Explanation:(According to UpToDate and Williams Obstetrics)
Gestational hyperandrogenism — Virilization in an XX individual with normal female internal
anatomy can result from exposure to maternal androgen or synthetic progestational agents. Because
the placenta produces the aromatase enzyme, which converts androgens to estrogens, only very
high levels of maternal androgens can overcome placental aromatase to cause virilization of the
fetus. Causes include maternal luteoma or theca lutein cysts. These disorders are suggested by a
history of maternal virilization during pregnancy and/or exogenous progestin or androgen
exposure
Contraindications to Pregnancy (Medications and Vaccines)
A 28-year-old female with history of recurrent pregnancy loss. She comes now
want to improve her immunity before trying to conceive. What you will give her?
A. Influenza vaccine
B. Rubella vaccine
C. Hepatitis
D. Immunoglobulin
3|Page
, Obstetrics and Gynecology: SMLE Questions and Answers Chapter 1: Obstetrics
Correct Answer: B
Explanation:(According to UpToDate )
Congenital rubella syndrome — Rubella infection can have catastrophic effects on the developing
fetus, resulting in spontaneous abortion, fetal infection, stillbirth, or intrauterine growth restriction
Female her previous pregnancy is stillbirth and now she want to pregnant and ask the doctor
about all the vaccines that she is need before conception and reduce the stillbirth?
A. Rubella
B. Varicella
C. Influenza
Correct Answer: A
Explanation:(According to UpToDate )
Congenital rubella syndrome — Rubella infection can have catastrophic effects on the developing
fetus, resulting in spontaneous abortion, fetal infection, stillbirth, or intrauterine growth restriction
Married women came in winter to OB /gyn clinic she want to conceive later what
vaccine you should give her before conceive?
A. Rubella
B. Influenza
C. Varicella
D. Tdap
Correct Answer: B
Explanation: (According to Williams Obstetrics and UpToDate)
PRECONCEPTION IMMUNIZATION
4|Page
Gynecology 2025 12th Edition questions and answers
2025
Female have regular cycle every 30 days her last period before 36, she received
rubella vaccine before 3 weeks. She was asked not to get pregnant until 2 months
of receiving rubella , But she got pregnant, what’s the most likely pregnancy
outcome?
A. Not affected
B. Associated with congenital malformations.
Correct Answer: A
Explanation: (According to Williams Obstetrics and UpToDate)
- Inadvertent administration of measles, mumps, rubella (MMR) or varicella
vaccines during pregnancy should not generally be considered indications
for pregnancy termination.
- ACIP and American College of Obstetricians and Gynecologists (ACOG)
recommendations to avoid pregnancy for one month following each dose of
a live vaccine. Nevertheless, adverse outcomes in women who became
pregnant soon after receiving these vaccines have not been established
Pregnant women doesnt have rubella vaccine what should do?
A. Take in second trimester.
B. Postpartum
Correct Answer: B
Explanation: (According to UpToDate)
POSTPARTUM IMMUNIZATION
- MMR and varicella – The following vaccines should be given before discharge
to protect a nonimmune mother and newborn:
o MMR – The measles, mumps, rubella (MMR) vaccine should be
administered to women nonimmune to rubella or measles
o Varicella vaccination is recommended for women without evidence of
immunity. The first dose is given while the patient is in the hospital and
the second dose is given four to eight weeks later, which typically
coincides with the routine postpartum visit. Breastfeeding is not a
contraindication to administration.
1|Page
,Obstetrics and Gynecology: SMLE Questions and Answers Chapter 1: Obstetrics
Pregnant her child school had an outbreak and she’s afraid to get to her child
which vaccine she should get ?
A. DtaP
B. Influenza
C. Rubella
D. Varicella
Correct Answer: B
Explanation: (According to UpToDate)
Inactivated Influenza Vaccine
- All women who are pregnant or might be pregnant during the influenza
season should receive the inactivated influenza vaccine as soon as it
becomes available and before onset of influenza activity in the community,
regardless of their stage of pregnancy
A woman was taking highly androgenic progesterone without knowing she is
pregnant. What complication will her daughter face?
A. Nothing will change
B. Hirsutism
C. Masculinization
D. Feminization
2|Page
,Current Diagnosis & Treatment Obstetrics &
Gynecology 2025 12th Edition questions and answers
2025
Correct Answer: C
Explanation:(According to UpToDate and Williams Obstetrics)
Gestational hyperandrogenism — Virilization in an XX individual with normal female internal
anatomy can result from exposure to maternal androgen or synthetic progestational agents. Because
the placenta produces the aromatase enzyme, which converts androgens to estrogens, only very
high levels of maternal androgens can overcome placental aromatase to cause virilization of the
fetus. Causes include maternal luteoma or theca lutein cysts. These disorders are suggested by a
history of maternal virilization during pregnancy and/or exogenous progestin or androgen
exposure
Contraindications to Pregnancy (Medications and Vaccines)
A 28-year-old female with history of recurrent pregnancy loss. She comes now
want to improve her immunity before trying to conceive. What you will give her?
A. Influenza vaccine
B. Rubella vaccine
C. Hepatitis
D. Immunoglobulin
3|Page
, Obstetrics and Gynecology: SMLE Questions and Answers Chapter 1: Obstetrics
Correct Answer: B
Explanation:(According to UpToDate )
Congenital rubella syndrome — Rubella infection can have catastrophic effects on the developing
fetus, resulting in spontaneous abortion, fetal infection, stillbirth, or intrauterine growth restriction
Female her previous pregnancy is stillbirth and now she want to pregnant and ask the doctor
about all the vaccines that she is need before conception and reduce the stillbirth?
A. Rubella
B. Varicella
C. Influenza
Correct Answer: A
Explanation:(According to UpToDate )
Congenital rubella syndrome — Rubella infection can have catastrophic effects on the developing
fetus, resulting in spontaneous abortion, fetal infection, stillbirth, or intrauterine growth restriction
Married women came in winter to OB /gyn clinic she want to conceive later what
vaccine you should give her before conceive?
A. Rubella
B. Influenza
C. Varicella
D. Tdap
Correct Answer: B
Explanation: (According to Williams Obstetrics and UpToDate)
PRECONCEPTION IMMUNIZATION
4|Page
