Chapter 01: Introduction to Pathophysiology
n n n n
VanMeter and Hubert: Gould’s Pathophysiology for the Health Professions, 7th Edition
n n n n n n n n n n
MULTIPLEnCHOICE
1. Whichnof nthenfollowingnwouldnbenthenmost nlikelyncausenof nanni
atrogenicn disease?
a. Anninherited n disorder
b. Ancombinationnof nspecificnetiologicalnfactors
c. Annunwanted neffect nof nanprescribed ndrug
d. Prolonged nexposurentontoxicnchemicalsninnthenenvironment
ANS:n C
2. Thenmanifestationsnof nandiseasenarenbest ndefined n asn the
a. subjectivenfeelingsnof ndiscomfort nduringnanchronicn illness.
b. signsnand nsymptomsn of nandisease.
c. factorsnthat nprecipitatenann acutenepisodenof nanchronicnillness.
d. earlynindicatorsnof nthenprodromaln stagenof ninfection.
ANS:n B
3. Thenbest n definitionn of nthen termn prognosisnisn the
a. precipitatingnfactorsncausingnannacutenepisode.
b. numbernof n remissionsn tonbenexpected n duringnthencoursenof nan chronicnillness.
c. predicted noutcomenornlikelihood nof nrecoverynfromnanspecificndisease.
d. exacerbationsn occurringn duringnchronicn illness.
ANS:n C
4. Whichnof nthenfollowingnisn considered n ansystemicnsignnof ndisease?
a. Swellingnof nthen knee
b. Fever
c. Painninnthenneck
d. Red nrashnonnthen face
ANS:n B
5. Etiologynisn defined n asn then studynof n the
a. causesnof nandisease.
b. coursenof nandisease.
c. expected ncomplicationsnof nandisease.
d. manifestationsnof nandisease.
ANS:n A
6. A ntypenof n cellularn adaptationn innwhichntherenisnandecreaseninn celln sizenisnreferred nton as
a. hypertrophy.
b. metaplasia.
c. anaplasia.
d. atrophy.
ANS:n D
7. A nchangeninn an tissuen marked n byncellsn thatnvaryninnsizen andnshapenandnshow nincreased n mitoticn fi
guresn would n ben called
,Test nBank nFornGould'snPathophysiology nfornthenHealthnProfessionsn7thnEditionnVanMeter 2
a. metaplasia.
b. atrophy.
c. dysplasia.
d. hypertrophy.
ANS:n C
8. A ndeficit n of noxygenn innthen cellsn usuallynduentonrespiratorynorn circulatorynproblemsn isn called
a. apoptosis.
b. ischemia.
c. hypertrophy.
d. necrosis.
ANS:n B
9. Whennan groupnof ncellsn inn thenbodyndies,nthen changen isn called
a. ischemia.
b. gangrene.
c. hypoxia.
d. necrosis.
ANS:n D
10. Rigorousnweightlifting/bodynbuildingnregimensn maynresult ninnthenskeletaln musclencellsn
undergoing
a. hypertrophy.
b. dysplasia.
c. atrophy.
d. regeneration.
ANS:n A
11. Thentermncancernrefersnto
a. dysplasia.
b. hyperplasia.
c. metaplasia.
d. malignant nneoplasm.
ANS:n D
12. Tonwhichnof nthenfollowingndoesn thentermnapoptosisn refer?
a. Increased nratenof nmitosisnbyncertainn cells
b. Ischemicndamagen ton cells
c. Liquefactionn of n necroticn tissue
d. Preprogrammed n celln self-destruction
ANS:n D
13. Whichnof nthenfollowingnstatementsnisnTRUE?
a. Alterationnof nDNA ndoesn not nchangencelln function.
b. Damaged ncellsnmaynbenablentonrepairnthemselves.
c. Allntypesnof ncellsn dienat nthensamenrate.
d. Mild nischemiancausesnimmediatencellndeath.
ANS:n B
14. Caseationnnecrosisnrefersntonannareanwhere
a. cellnproteinsnhavenbeenndenatured.
,Test nBank nFornGould'snPathophysiology nfornthenHealthnProfessionsn7thnEditionnVanMeter 3
b. cellsnarenliquefied n bynenzymes.
c. dead ncellsnformnanthickn cheesynsubstance.
d. bacterialn invasionn hasn occurred.
ANS:n C
15. Routinenapplicationn of nsunn blockntonskinn would nben annexamplenof
a. anniatrogenicncausenof ncancer.
b. anpreventiven measure.
c. anprecipitatingnfactor.
d. anpredisposingn condition.
ANS:n B
16. A ncircumstancenthat n causesnansuddenn acutenepisoden of nanchronicndiseasenton occurnisn termed
a. latent nstage.
b. predisposingnfactor.
c. incidence.
d. precipitatingn factor.
ANS:n D
17. Thentermnhomeostasisnrefersnto
a. thencausativenfactorsninnanparticularndisease.
b. maintenancenof nanstableninternalnenvironment.
c. anconditionnthat ntriggersnannacutenepisode.
d. ancollectionnof nsignsnand nsymptoms.
ANS:n B
18. Whichntermn isnused n tondescribenannew nand nsecondarynornadditionalnproblemn that narisesn afterntheno
riginaln diseasen hasn beenn established?
a. Symptoms
b. Occurrence
c. Manifestations
d. Complication
ANS:n D
19. Pathophysiologyninvolvesnthenstudynof
a. thenstructurenof nthenhumann body.
b. thenfunctionsn of nvariousn organsn innthenbody.
c. functionalnornstructuralnchangesnresultingnfromndiseasenprocesses.
d. variousncellnstructuresnand nrelated nfunctions.
ANS:n C
20. Whichnof nthenfollowingnisn thenbest n definitionn of nepidemiology?
a. Thensciencenof ntrackingnthenoccurrencenand ndistributionn of ndiseases
b. Thenrelativennumbernof ndeathsnresultingnfromnanparticularndisease
c. Identificationnof nanspecificndiseasenthroughnevaluationnof nsignsnand nsymptoms
d. Thenglobalnsearchnfornemergingndiseases
ANS:n A
, Test nBank nFornGould'snPathophysiology nfornthenHealthnProfessionsn7thnEditionnVanMeter 4
21. Whichnof nthenfollowingncann causencelln injurynorn death?
1. Hypoxia
2. Exposurentonexcessivencold
3. Excessivenpressurenonnantissue
4. Chemicaln toxins
a. 1,n 2
b. 2,n 4
c. 1,n 3,n 4
d. 1,n 2,n 3,n 4
ANS:n D
22. Allnof nthenfollowingn arenpart nof nthenSevenn Stepsnton Healthn EXCEPT:
a. Follow n cancernscreeningn guidelines.
b. Usensunnblocknagentsnwhenevernexposed.
c. Participateninnstrenuousnexercisenonnanregularndailynbasis.
d. Choosenhighnfiber,nlowern fat nfoods.
ANS:n C
23. Thentermndiseasenrefersnto
a. thenperiod nof nrecoverynand n returnnton annormaln healthynstate.
b. andeviationnfromn thennormaln statenof nhealthnand n function.
c. thentreatment nmeasuresnused ntonpromotenrecovery.
d. anbasicncollectionn of nsignsn and nsymptoms.
ANS:n B
24. A ncollectionnof nsignsn and n symptoms,n oftennaffectingnmorenthannonenorgannorn system,nthatnu
suallyn occurn togethern inn responsen ton an certainn conditionn isn referred n ton asn a(an)
a. acutendisease.
b. multiorganndisorder.
c. syndrome.
d. manifestation.
ANS:n C
25. Allnof nthenfollowingnstatementsnarencorrect n about n celln damagenEXCEPT:
a. Theninitialnstagenof ncellndamagenoftenncausesnann alterationninnmetabolicnreactions.
b. If nthenfactorncausingnthendamagenisn removed nquickly,n thencelln maynbenablenton r
ecovern and n returnn ton itsn normaln state.
c. If nthennoxiousn factornremainsn fornannextendednperiod nofntime,nthendamagenbecomesn i
rreversiblen and n then celln dies.
d. Initially,ncellndamagendoesnnot nchangencellnmetabolism,nstructure,nornfunction.
ANS:n D
26. Whichnof nthenfollowingnconditionsndistinguishesndoublenblind nstudiesnused ninnhealthnresearch?
a. Neithernthenmembersnof nthencontroln groupnornthenexperimentaln groupnnornthenpersonna
dministeringn then treatment n knowsn whon isn receivingn then experimentaln therapy.
b. Bothngroupsnof nresearchnsubjectsn and nthenpersonnadministeringnthentreatment nknownwhoni
sn receivingn then experimentaln therapy.
c. Thenresearchnsubjectsn don not n know,nbutn thenpersonnadministeringnthentreatment n
knowsn whon isn receivingn placebon orn standard n therapy.
d. Onlynmembersnof nthen controlngroupn know ntheynaren receivingnstandard ntherapy.