PED1003 EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS GRADED A++

PED1003 EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS GRADED A++ Which type of antibiotics targets the elongation phase of translation by binding to the 30s ribosomal subunit? Tetracyclines How does Tetracyclines work? Inhibit tRNA from binding In what phases are drugs tested on healthy participants rather than individuals with the condition? Phase I and II In terms of Non-adrenergic Non-cholinergic innervation of respiratory mechanisms, what is an inhibitory mediator? Nitric Oxide What does NA bind with to activate phospholipase C, causes pupils to dilate, vessels to the visceral organs to constrict and brain alertness to increase Alpha-1 adrenoreceptor what do macrolides do? block protein synthesis by binding to the 50s subunit of prokaryotic ribosomes Which of the CYPs are involved in the metabolism of paracetamol and caffeine? CYP1A2 Which cells undergo apoptosis due to acidification of the tumour microenvironment via the release of lactate? NK cells CD8 T cells In NA synthesis, which enzyme converts dopamine into NA within the vesicles? DA beta-hydroxylase Which type of amphetamine has the highest affinity for the DAT transporter? Methamphetamines What does the Gi part of the alpha subunit of a G protein coupled