PED1003 13 ASTHMA EXAM QUESTIONS AND ANSWERS
WITH COMPLETE SOLUTIONS GRADED A++ LATEST
UPDATE
What does parasympathetic innervation control?
Bronchial and vascular smooth muscle amd glands
What neurotransmitter is used during parasympathetic innervation?
Acetylcholine
What receptor does the acetylcholine bind to in parasympathetic innervation?
M3 cholinergic receptors
What does the binding of ACh to M3 receptors trigger an increase in?
IP3
What is the result of parasympathetic innervation stimulation?
Bronchoconstriction and increased mucus
What does sympathetic innervation control?
Bronchial smooth muscle
What is the neurotransmitter used in sympathetic innervation?
Adrenaline
What does adrenaline bind act on in sympathetic innervation?
Beta 2 receptors
, When adrenaline binds to beta 2 receptors in sympathetic innervation, the levels
of what are increased?
cAMP
What does sympathetic innervation stimulation result in?
Smooth muscle relaxation and bronchodilation
Are there noradrenaline receptors in bronchial tissue?
No
What is asthma?
recurrent reversible obstruction of the airways in response to a stimuli which are not
themselves noxious and do not cause the syndrome in non-asthmatics
What causes asthma?
Contraction of airway smooth muscle and mucus hyper secretion/thickening
What are the symptoms of asthma?
Dyspnoea (difficult, laboured breathing), wheezing and coughing
What are the two phases of asthma?
immediate phase and late phase
What happens during the immediate phase of asthma?
Bronchoconstriction on exposure to stimuli/allergen
What happens during the late phase of asthma?
Inflammation/damage in response to inflammatory mediators
When are spasmogens-histamine leukotrienes and chemotaxins released?
During immediate phase of asthma
What causes the delayed phase of asthma?
WITH COMPLETE SOLUTIONS GRADED A++ LATEST
UPDATE
What does parasympathetic innervation control?
Bronchial and vascular smooth muscle amd glands
What neurotransmitter is used during parasympathetic innervation?
Acetylcholine
What receptor does the acetylcholine bind to in parasympathetic innervation?
M3 cholinergic receptors
What does the binding of ACh to M3 receptors trigger an increase in?
IP3
What is the result of parasympathetic innervation stimulation?
Bronchoconstriction and increased mucus
What does sympathetic innervation control?
Bronchial smooth muscle
What is the neurotransmitter used in sympathetic innervation?
Adrenaline
What does adrenaline bind act on in sympathetic innervation?
Beta 2 receptors
, When adrenaline binds to beta 2 receptors in sympathetic innervation, the levels
of what are increased?
cAMP
What does sympathetic innervation stimulation result in?
Smooth muscle relaxation and bronchodilation
Are there noradrenaline receptors in bronchial tissue?
No
What is asthma?
recurrent reversible obstruction of the airways in response to a stimuli which are not
themselves noxious and do not cause the syndrome in non-asthmatics
What causes asthma?
Contraction of airway smooth muscle and mucus hyper secretion/thickening
What are the symptoms of asthma?
Dyspnoea (difficult, laboured breathing), wheezing and coughing
What are the two phases of asthma?
immediate phase and late phase
What happens during the immediate phase of asthma?
Bronchoconstriction on exposure to stimuli/allergen
What happens during the late phase of asthma?
Inflammation/damage in response to inflammatory mediators
When are spasmogens-histamine leukotrienes and chemotaxins released?
During immediate phase of asthma
What causes the delayed phase of asthma?
