Adv Patho NGR 6152 - Exam 1 questions with correct answers

Adv Patho NGR 6152 - Exam 1 questions
with correct answers

What cis cthe cComplement cSystem cmade cup cof cand cwhat care cits cfunctions? c-
cCORRECT cANS✔✔A cgroup cof cabout c30 cproteins cthat cmay camplify cthe
cinflammatory cresponse, cenhance cphagocytosis, cor clyse cpathogens


Antigen c- cCORRECT cANS✔✔toxin cor cforeign csubstance cthat cinduces cimmune
cresponse cin cthe cbody, cespecially cantibody cproduction


Epitope c- cCORRECT cANS✔✔part cof cthe cantigen cwhere cthe cantibody cattaches
citself


For can ceffective cimmune cresponse, can cantigen cmust cbe c_ c- cCORRECT
cANS✔✔processed cwithin cthe ccell cand cexpressed con cthe csurface cof cthose ccells


Antibodies care calso ccalled c- cCORRECT cANS✔✔immunoglobulins

IgG c- cCORRECT cANS✔✔- cmost cabundant cIg
- cprotects cagainst cinfections
- cable cto ccross cplacenta cand cprovide cpassive cimmunity

Toll-like creceptors c(TLRs) c- cCORRECT cANS✔✔attach cto cpathogen-associated
cmolecular cpatters c(PAMPs) con ca chost ccell


Classical cPathway c- cCORRECT cANS✔✔activated cby cantibodies cbound cto can
cantigen, cwhich cinteract cwith cthe ccomplement csystem


Lectin cPathway c- cCORRECT cANS✔✔activated cwhen cmannose cbinding cproteins
cbind cto cmannose cresidues con cthe csurface cof cthe cpathogens


Alternative cPathway c- cCORRECT cANS✔✔activated cby cgram cnegative cbacteria cand
cfungi ccell cwall cpolysaccharides


Mast cCell cDegranulation c- cCORRECT cANS✔✔- cHistamine cRelease
- cVasoactive camine cthat ccauses ctemporary, crapid cconstriction cof clarge cblood
cvessels cand cdilation cof cpostcapillary cvenules


Cytokines c- cCORRECT cANS✔✔chemicals creleased cby cthe cimmune csystem cto
ccause cPRO cor cANTI cinflammatory cresponse

, Dendritic cCells c- cCORRECT cANS✔✔antigen cpresenting ccells con cthe cskin

Diapedesis c- cCORRECT cANS✔✔passage cof cblood ccells c(WBC) cthrough ccapillary
cwalls cand cinto csurrounding ctissue


Natural cKiller c(NK) cCells c- cCORRECT cANS✔✔- crole cin ckilling cof ccells cinfected cby
cvirus cand cmalignant ccells
- cresponsible cfor cimmunological csurveillance cand cpolicing cperipheral ctissues

Bradykinin c- cCORRECT cANS✔✔increases cvascular cpermeability, csmooth cmuscle
ccontraction, cand cpain


Chronic cInflammation c- cCORRECT cANS✔✔continuous cinjury/irritation cto ctissue,
ccharacterized cby cdense cinfiltration cof clymphocyte cand cformation cof cgranuloma


Membrane cAttack cComplex c(MAC) c- cCORRECT cANS✔✔components cof cthe
ccomplement csystem cthat cassemble cto cform cpores cin cthe cmembranes cof cinvading
ccells


Anaphylatoxins c- cCORRECT cANS✔✔- cC3a c& cC5a
- cstimulate cmast ccells cto crelease chistamine

Chemotactic cFactors c- cCORRECT cANS✔✔attract cphagocytes cto csite cof
cinflammation


Function cof cthe cclotting csystem c- cCORRECT cANS✔✔prevent cspread cof cinfection cor
cadjacent ctissues


The ccoagulation ccascade cis cdependent con c_ cand cconverges cat c_ c- cCORRECT
cANS✔✔- ccalcium
- cfactor cX

Coagulation cExtrinsic cPathway c- cCORRECT cANS✔✔activated cby cdamaged ctissues
creleasing cfactors


Coagulation cIntrinsic cPathway c- cCORRECT cANS✔✔activated cby cexposed ccollagen

What cis cthe cend cproduct cof cthe ccoagulation ccascade? c- cCORRECT cANS✔✔Fibrin

Paratope c- cCORRECT cANS✔✔antigen cbinding csite

What cproduces cimmunoglobulins? c- cCORRECT cANS✔✔plasma ccells

IgM c- cCORRECT cANS✔✔First cantibody cproduced