UNDERSTANDING MEDICAL-
SURGICAL NURSING 6TH
EDITION BY LINDA S.
WILLIAMS; PAULA D. HOPPER
CHAPTER 1-57 EXAM 2025
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Chapter 1
What are the four processes in which pain is transmitted?
Transduction
Transmission
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,Test Bank for Understanding Medical-Surgical Nursing
6th Edition Linda S. Williams Paula D.
Hopper
Perception
Modulation
Transduction
represents the initiation of the stimulus and conversion of that stimulus into an electrical
impulse at the time of the injury
Neurotransmitters
chemical substances released from damaged tissue
What substances are included in neurotransmitters?
prostaglandins, bradykinin, serotonin, and substance P
Transmission
the process of moving a painful message from the preipheral nerve ending through the
dorsal root ganglion and the acending tract of the spinal cord to the brain
Perception
actually feeling the pain
What is the response of the hypothalamus during perception?
activates and controls emotional input and also generates purposeful goal directed
behavior
What receives the pain message during perception?
cerebral cortex
Modulation
the body's attempt to interrupt pain impulses by releasing endogenous (naturally
occurring) opioids
Endorphins
endogenous chemicals that act like opioids; inhibiting pain impulses in the spinal cord
and brain
Enkephalins
one type of endorphin
What degrades too quickly to be considered an effective analgesic?
endorphins
What are the mechanisms of pain transmission?
nocicpetive and neuropathic
Nociception
the body's normal reaction to noxious stimuli, such as tissue damage, with the release of
pain producing substances.
What is referred pain?
nociceptive pain in the visceral organs that may be felt in other parts of the body
Neuropathic Pain
pain associated with injury to either the peripheral or central nervous system; not
localized and may spread to involve other areas along the nerve pathway
What is pain?
whatever the experiencing person says it is, existing whenever the experiencing person
says it does
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, _________ often accompanies pain.
suffering
What is the most common reason that patients as for more pain medicine?
because they have increased pain
What is tolerance?
a normal biological adaptation (takes a larger dose to provide the same level of pain
relief)
What is physical dependence?
a normal physiological phenomenon that most people experience after a few weeks of
continuous opioid use
What are the signs and symptoms of opioid withdrawal syndrome?
sweating, tearing, runny nose, restlessness, irritability, tremors, dilated pupils,
sleeplessness, nausea, vomiting, and diarrhea
How can opioid withdrawal syndrome be prevented?
by weaning a patient slowly from an opioid rather than stopping it suddenly.
What is psychological dependence?
behaviors that include one or more of the following: impaired control over drug use,
compulsive use, continued use despite harm, and craving
What is pseudoaddiction?
patients that are receiving opioid doses that are too low or spaced too far apart to relieve
their pain, and certain behavioral characteristics resembling psychological dependence
such as drug-seeking behaviors have developed
A patient with pseudoaddiction stops drug seeking behaviors when the _______ is
relieved.
pain
Acute pain
pain that follows injury to the body, prompting an inflammatory response, and subsides
as healing take place
What are the short term, objective, physical signs associated with acute pain?
increased heart rate and elevated blood pressure
What are examples of acute pain?
fractures, burns, or other trauma
Cancer related pain
may be acute, chronic, or intermittent; has a definable cause such as a tumor invasion or
neuropathy caused by the cancer treatment
Chronic nonmalignant pain
persists beyond the time when healing usually takes place, such as low back pain, the
pain accompanying arthritis, and phantom limb pain
Because of the body's ability to adapt, patients with ___________ of ____________ may
not appear to be in pain
chronic non malignant pain or chronic cancer pain; the physiological responses that
accompany acute pain, such as elevated heart rate and blood pressure, cannot be sustained
without harm to the body, so the body adapts and vital signs return to normal
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, Test Bank for Understanding Medical-Surgical Nursing
6th Edition Linda S. Williams Paula D.
Hopper
What is a malingerer?
pretending to be in pain or drug seeker
What is an analgesic?
a drug that relieves pain
Opioids
are classified by their ability to bind to opioid receptors in the brain, spinal cord, and
other areas of the body, inhibiting the perception of pain
Nonopioids
the first class of drugs used to treat mild pain; used for acute and chronic pain from a
variety of causes such as surgery, trauma, arthritis, and cancer
What are some causes that nonopioids may be used?
surgery, trauma, arthritis, and cancer
What is the ceiling effect?
a dose beyond which there is no improvement in the analgesic effect, but there may be an
increase in adverse effects
What classification of drugs do no produce tolerance or physical dependency?
nonopioids
What effects do most nonopioids have?
antipyretic (fever reducing)
How does nonopioids work?
work mainly peripherally, at the site of injury
What nonopioid drug is excluded from working peripherally, at the site of injury?
acetaminophen; believed to act on the central nervous system
How does NSAIDs work?
block the synthesis of prostaglandins (chemical needed for pain transmission)
Fentanyl patch is useful for patients with __________ and should be replaced with a new
patch every ________ days.
stable cancer pain; 3 days
What drug is used in drug treatment programs during detoxification from heroin and
other opioids?
Methadone (Dolophine)
_____________ is a potent analgesic that has a longer duration of action than morphine.
Methadone (Dolophine)
____________ is a pure opioid antagonist that counteracts, or antagonizes, the effect of
opioids.
Naloxone (Narcan)
What drug is often used in emergency departments for treating the effects of opioid
overdose, such as sedation and respiratory depression.
Naloxone (Narcan)
Which chemical do NSAIDs block?
prostraglandins
What drug classification have similar actions to those of morphine?
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