Abrams' Clinical Drug Therapy: Rationales for Nursing P
j j j j j j j
ractice 12th EditionFrandsen Test B
j j j j j
ank
,Abrams'jClinicaljDrugjTherapy:jRationalesjforjNursingjPracticej12th jEdition jFrandsen jTestjBank
Chapterj 1j Thej Foundationj ofj Pharmacology: j Quality j andj Safety
Ajwoman j hasjbeen jprescribed jparoxetine jhydro
chloride,j which j isj an j antidepressantjagentjadmi
nistered jin jpilljform.jThejmedication j isj administ
1.
ered j forj herj obsessive-
jc ompulsive jdisorder. jThis j medication j will
produce j which j of j thej followingj effects?
A) Curative
B) Systemic
C) Local
D) Parenteral
Ans: B
Feedback:
Drugsj thatj produce j systemic j effectsj arejtakenjint
o jthejbody,jcirculated jthrough jthejbloodstream j t
o j theirj sitesj of j action j in jvariousjbody j tissues,jand
j eventually j eliminated j fromjthe jbody. jCurative ja
gentsjarejgiven jto jcurejajdiseasejprocess.jIn jthisjc
ase,jparoxetine jhydrochloridej willj controlj thej sy
mptomsj butjnotj curej thej disorder.j Drugsj with j lo
calj effects,jsuch jasjsunscreen jand jlocaljanestheti
cs,jactjmainly jatjthejsitejof japplication.j Paroxetin
ejhydrochloride jisj notj administered jparenterall
y.j Parenteralj agentsj arejadministered j subcutane
ously,j intramuscularly,
orj intravenously.
Ajpatientj hasj been jprescribed j an j antibiotic.jThi
sjmedication jisjajnaturally joccurringjsubstance j
2. thatj hasj been j chemically j modified.jWhatjisjano
therjname jforjthisjtypejof
medication?
A) Synthetic j drug
B) Semisynthetic j drug
C) Biotechnology j drug
D) Prototype j drug
Ans: B
Feedback:
,Abrams'jClinicaljDrugjTherapy:jRationalesjforjNursingjPracticej12th jEdition jFrandsen jTestjBank
Semisynthetic j drugsj (e.g.,j many j antibiotics)jarej
naturally j occurringj substancesjthatj havejbeen jch
emically j modified.j Synthetic j drugsj arejmorejsta
ndardized jin jtheirjchemicaljcharacteristics, jmorej
consistentj in j theirjeffects,jand jlessjlikely jto jprod
ucejallergicjreactions.jBiotechnology jdrugsjinvo
lvejmanipulatingj DNAjand j RNAjand jrecombini
ngj genesj into j hybrid j moleculesj thatjcan jbejinsert
ed jinto jlivingjorganisms.
Prototype jdrugsjarejthejfirstjdrugjof ja
particularj group j to j bej developed.
Ajpatientj isj administered j morphine.j Morphine jis
ja j prototypicalj drugj thatj canj be jclassifiedj in jdiffe
3.
rentjways.jWhich jof jthejfollowing
classificationsj appliesj to j morphine?
A) Centralj nervousj system j depressant
B) Centralj nervousj system j stimulant
C) Anti-inflammatory
D) Antihypertensive
Ans: A
Feedback:
Drugsj arej classified j accordingj to j theirj effectsjonj
particularj body j systems,jtheirj therapeutic juses,j a
nd j theirj chemicalj characteristics. j Forjexample,j
morphine jcan jbejclassified jasjajcentraljnervousjs
ystemjdepressantjand jajnarcoticj orj opioid j analge
sic.jAjcentralj nervousjsystem jstimulantj increases
j attention j and jraises jmood. jAn janti-
inflammatory jagentjdecreasesj inflammation j atj t
hej sitej of j tissuejorjjointj inflammation. jAn j antihy
pertensive j agent
reducesj blood j pressure.
Ajpatientjisjadministered jamoxicillin j(Amoxil)
.jThejgenericjname jof jthisjmedication j indicates
4.
j thatj itj belongs j to j which
drugj group?
A) Selectivej serotonin j reuptake j inhibitors
B) Diuretics
C) Penicillins
D) ACEj inhibitors
Ans: C
, Abrams'jClinicaljDrugjTherapy:jRationalesjforjNursingjPracticej12th jEdition jFrandsen jTestjBank
Feedback:
Thejgenericjnamejoften j indicatesjthejdrugjgroup
j (e.g., j drugs j with j generic j names j endingjin j “cilli
n”j arej penicillins).j Selectivej serotonin jreuptake j
inhibitorsj arej medicationsj thatj havejantidepress
antjeffects;jSSRIjisjajbroad jclassification, jnotj ajg
enericj name.jDiureticsjarej medicationsjthatj incr
easej urinej output;jdiureticjisj aj broad j classificati
on,j notj aj genericjn ame.jACEj inhibitorj isjthej broa
d jclassification j forj thej angiotensin-converting
enzyme j inhibitors,j notj thej generic j name.
o
Thejadministration jof jdiphenhydramine j(Benadr
c
5.
p.
yl),jwhich jisjan jover-the-
counterjmedication,j isj regulated j by j whichj govern
ment
agency?
r e
A)
t p
Publicj Health j Service
B)
s
FederaljTradej Commission
e
C)
g t
Occupationalj Safety j and j Health
Administration
D)
Ans: i n Food j and j DrugjAdministration
D
r s Feedback:
u Thej Food j and j DrugjAdministration j approvesjd r
yn
ugsjforjover-the-
counterjavailability,jincludingjthejtransferjof jdru
.m
gsjfromjprescription j to j OTCj status,j andj mayj req
uirejclinicaljtrialsjto jdetermine jthejsafety jand jeff
w ectivenessj of j OTCj use.jThej Publicj Health jServi
w cej isj regulated j by j thejstatej to jmaintain jthej healthj
of j individualj citizensjofjthej state.jThejFederaljTr
w adejCommission jregulatesjimportsj and j exportsj t
hroughoutj thej nation.
Thej Occupationalj Safety j and j Health
Administration j regulatesj safety j within j thejwork
place.
Thej administration j of j anabolic j steroidsj is
6.
regulated j by j which j of j thej followingj laws?
A) Thej Food,j Drug,j and j Cosmetic jActj of j 1938
Thej Comprehensive j DrugjAbuse j Prevention
B)
and j ControljAct
C) Thej Harrison j Narcotic jAct