N201 METABOLISM MEDICATIONS EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS GRADED A++ LATEST UPDATE

N201 METABOLISM MEDICATIONS EXAM QUESTIONS AND ANSWERS WITH COMPLETE SOLUTIONS GRADED A++ LATEST UPDATE repaglinide meglitinides glipizide glyburide sulfonylureas metformin biguanides sitagliptin DPP-4 inhibitors acabose miglitol alpha-glucosidase inhibitors dapagliflozin canagliflozin SGLT2 inhibitors stimulates a rapid and short lived release of insulin from the pancreas meglitinides slows absorption and digestion of CHO from the GI tract it is most effective in lowering post prandial blood glucose aka as starch blocker alpha glucosidase inhibitors decreases the rate of glucose that is released by the liver; improves the body's ability to use insulin by increasing glucose uptake by tissue, especially muscles biguanides increases insulin production by the pancreas; enhances cellular sensitivity to insulin; helps release insulin already made sulfonylureas blocks the reabsorption of glucose by the kidney, increasing glucose excretion, which is helpful in lowering blood glucose levels SGLT2 inhibitors enhances the incretin system; stimulates release of insulin from pancreatic beta cells and decreases hepatic glucose production DPP-4 inhibitors take within 1-30 minutes before meals meglitinides take with the first bite of each meal alpha-glucosidase inhibitors take 30 minutes after meals to with meals to reduce GI effects biguanides take 30 minutes before meals sulfonylureas assess for s/s of hypoglycemia sulfonylureas & meglitinides assess for excessive flatus, abdominal pain and distention, diarrhea, and jaundice alpha glucosidase inhibitors assess for s/s of lactic acidosis