controlled substances quiz, 578 u2
1. codeine: abused prescription drug, second-most
2. Comprehensive Drug Abuse Prevention and Control Act: Act also known as
the Controlled Substance Act (1970)
3. transmuscosal fentanyl only approved for breakthrough cancer pain in
opioid tolerant patients: actiq
4. dopamine reward circuit: addictive drugs all activate the brain's _________ 5.
naltrexone: after detox, an opioid addict can be rx'd ___________ to
discourage renewed opioid abuse
6. for appetite stim: AIDS patients use Dronabinol (marinol)
7. used for tx of opioid-induced ileus: alvimopan
8. II: amphetamines are schedule
9. norepinephrine; dopamine: amphetamines work primarily by promoting
neuronal release of _________ & ___________, and partly by blocking their
reuptake
10. insomnia; weight loss: amphetamines, most common adverse effects
11. opioids: analgesics, most effective available
12. extended release morphine: avinza
13. none, just supportive treatment: barbiturate OD antidote?
14. opioid OD: barbiturate OD produces same classic triad of symptoms (resp.
depression, coma, pinpoint pupils) as seen with
15. opioids: barbiturate tolerant individuals are cross-tolerant to other CNS
depressants (alcohol, benzos, general anesthetics) but not with ________
16. addiction: behavior pattern characterized by continued use of a psychoactive
substance despite physical, psychologic, or social harm
17. anxiety, insomnia, seizure disorders: benzodiazepine principal indications
are
18. daytime sedation; anterograde amnesia: benzodiazepines adverse effects
19. IV: benzodiazepines are classified as Schedule
20. panic disorder, GAD: benzodiazepines are primarily for which two anxiety
d/o's
21. GABA: benzodiazepines produce their actions by enhancing the effects of
_____, the principal inhibitory neurotransmitter in the CNS
22. eszopiclone (Lunesta): benzodiazepines-like controlled substace approved
for long-term use in insomnia
23. a component of REMS: black box warnings
, controlled substances quiz, 578 u2
24. methadone, tramadol, buprenorphine (suboxone): bridging agents
commonly abused
25. subutex or suboxone SL: buprenorphine formulations used in management
of opioid addiction
26. increase cardiac work: butorphanol (stadol) and nalbuphne (nubain) are
contraind. In MI as they
27 21: butrans transdermal sites must be rotated. No site may be reused within
___ days
28. frequently undertreated, able to be mitigated in 90% of cases with
proper dosing/drug therapy (consider adjuvants): cancer pain
29. ORT (opioid risk tool); SOAPP (screener and opioid assessment for
patients with pain); DIRE (diagnois, intractability, risk, and efficacy score):
chronic opioid therapy candidates can be identified with 30. 50-70% of the time:
chronic opioid therapy fails
31. issuance & filling of prescriptions: code of fed regulations, title 21, section
1306 governs
32. II, V: codeine by itself is a schedule ___ CS. In cough meds, it's often
schedule ___
33. adjuvant analgesics: complement effects of opioids (in combo with, not in
substitution of)
34. establishes regulations for controlled substances for manufacturers,
prescribers, pharmacists, and distributors: Comprehensive Drug Abuse
Prevention and Control Act (1970)
35. Controlled Substance Act: Comprehensive Drug Abuse Prevention and
Control Act (1970) aka
36. any drug whose use is controlled by fed gov.: controlled substance
definition
37. actual number & numerical value: controlled substance prescriptions require
38. general CNS depressants: cross-tolerance does not exist between opioid
agonists and
39. various opioid agonists: cross-tolerance exists among
40. FALSE: DEA only regs dispensing of controlled subs, T or F
41. TRUE: depression treatment for individuals that did not respond to other tx
may include stimulants, T or F
42. appetite stimulant: Dronabinol (marinol
43. benzos; SSRIs: drug classes most often used for tx of anxiety disorders
44. methadone: drug only available through Opioid Treatment Programs
, controlled substances quiz, 578 u2
45. cross-dependence: drug that has the ability to support physical dependence
on another drug is said to have
46. abuse: drug use that is inconsistent with medical or social norms
47. pure opioid agonists: drugs that activate mu and kappa receptors, producing
analgesia, sedation, euphoria, resp. depression, physical dependence,
constipation, and cough supression
48. opioid antagonists: drugs that block the mu & kappa receptors to cause
reversal of sedation/resp. depression caused by opioid overdose
49 DEA: enforcing agency for the Comprehensive Drug Prevention & Control Act
1970
50. 25-50: equianalgesic table: switching opioids (other than fentanyl or
methadone), decrease the dose rec. in the table by __________ % to account
for polymorphisms or enhanced sensitivity to new opioids
51. Comprehensive Drug Abuse Prevention and Control Act: establishes
regulations for controlled substances for manufacturers, prescribers,
pharmacists, and distributors
52. naloxone auto-injector pen: Evzio, aka ____________, was fast-tracked
through FDA approval to help prevent OD on rx or illicit opioids
53. avinza: extended release morphine is called
54. 100 times more potent than morphine: Fentanyl
55. direct heat: fentanyl patch use education: warn pts to avoid exposing patch to
_______, because doing so can accelerate drug release
56. ARE NOT: fentanyl products ARE/ARE NOT interchangeable on an mg-by-mg
basis
57. can be used to treat benzo OD: Flumazenil
58. a benzo receptor antagonist: Flumazenil
59. SHORTER: half-life of naloxone is ___________ than half-lives of opioids
60. zohydro: hydrocodone sustained-release formulation that has no abuse-
deterrent properties and therefore its approval is currently being called to be
revoked 61. the emergence of a new pain syndrome refractory to tx & is
atypical or unrelated to original pain: hyperalgesia
62. cognitive behavior therapy (CBT): insomnia first-line treatment (even if
drugs are also employed)
63. code of fed regulations title 21 section 1306 and the United States Code--
controlled substances act title 21 section 829: issuance and filling of
prescriptions is governed by
64. infrequent: Issuance and filling of prescriptions is governed by
1. codeine: abused prescription drug, second-most
2. Comprehensive Drug Abuse Prevention and Control Act: Act also known as
the Controlled Substance Act (1970)
3. transmuscosal fentanyl only approved for breakthrough cancer pain in
opioid tolerant patients: actiq
4. dopamine reward circuit: addictive drugs all activate the brain's _________ 5.
naltrexone: after detox, an opioid addict can be rx'd ___________ to
discourage renewed opioid abuse
6. for appetite stim: AIDS patients use Dronabinol (marinol)
7. used for tx of opioid-induced ileus: alvimopan
8. II: amphetamines are schedule
9. norepinephrine; dopamine: amphetamines work primarily by promoting
neuronal release of _________ & ___________, and partly by blocking their
reuptake
10. insomnia; weight loss: amphetamines, most common adverse effects
11. opioids: analgesics, most effective available
12. extended release morphine: avinza
13. none, just supportive treatment: barbiturate OD antidote?
14. opioid OD: barbiturate OD produces same classic triad of symptoms (resp.
depression, coma, pinpoint pupils) as seen with
15. opioids: barbiturate tolerant individuals are cross-tolerant to other CNS
depressants (alcohol, benzos, general anesthetics) but not with ________
16. addiction: behavior pattern characterized by continued use of a psychoactive
substance despite physical, psychologic, or social harm
17. anxiety, insomnia, seizure disorders: benzodiazepine principal indications
are
18. daytime sedation; anterograde amnesia: benzodiazepines adverse effects
19. IV: benzodiazepines are classified as Schedule
20. panic disorder, GAD: benzodiazepines are primarily for which two anxiety
d/o's
21. GABA: benzodiazepines produce their actions by enhancing the effects of
_____, the principal inhibitory neurotransmitter in the CNS
22. eszopiclone (Lunesta): benzodiazepines-like controlled substace approved
for long-term use in insomnia
23. a component of REMS: black box warnings
, controlled substances quiz, 578 u2
24. methadone, tramadol, buprenorphine (suboxone): bridging agents
commonly abused
25. subutex or suboxone SL: buprenorphine formulations used in management
of opioid addiction
26. increase cardiac work: butorphanol (stadol) and nalbuphne (nubain) are
contraind. In MI as they
27 21: butrans transdermal sites must be rotated. No site may be reused within
___ days
28. frequently undertreated, able to be mitigated in 90% of cases with
proper dosing/drug therapy (consider adjuvants): cancer pain
29. ORT (opioid risk tool); SOAPP (screener and opioid assessment for
patients with pain); DIRE (diagnois, intractability, risk, and efficacy score):
chronic opioid therapy candidates can be identified with 30. 50-70% of the time:
chronic opioid therapy fails
31. issuance & filling of prescriptions: code of fed regulations, title 21, section
1306 governs
32. II, V: codeine by itself is a schedule ___ CS. In cough meds, it's often
schedule ___
33. adjuvant analgesics: complement effects of opioids (in combo with, not in
substitution of)
34. establishes regulations for controlled substances for manufacturers,
prescribers, pharmacists, and distributors: Comprehensive Drug Abuse
Prevention and Control Act (1970)
35. Controlled Substance Act: Comprehensive Drug Abuse Prevention and
Control Act (1970) aka
36. any drug whose use is controlled by fed gov.: controlled substance
definition
37. actual number & numerical value: controlled substance prescriptions require
38. general CNS depressants: cross-tolerance does not exist between opioid
agonists and
39. various opioid agonists: cross-tolerance exists among
40. FALSE: DEA only regs dispensing of controlled subs, T or F
41. TRUE: depression treatment for individuals that did not respond to other tx
may include stimulants, T or F
42. appetite stimulant: Dronabinol (marinol
43. benzos; SSRIs: drug classes most often used for tx of anxiety disorders
44. methadone: drug only available through Opioid Treatment Programs
, controlled substances quiz, 578 u2
45. cross-dependence: drug that has the ability to support physical dependence
on another drug is said to have
46. abuse: drug use that is inconsistent with medical or social norms
47. pure opioid agonists: drugs that activate mu and kappa receptors, producing
analgesia, sedation, euphoria, resp. depression, physical dependence,
constipation, and cough supression
48. opioid antagonists: drugs that block the mu & kappa receptors to cause
reversal of sedation/resp. depression caused by opioid overdose
49 DEA: enforcing agency for the Comprehensive Drug Prevention & Control Act
1970
50. 25-50: equianalgesic table: switching opioids (other than fentanyl or
methadone), decrease the dose rec. in the table by __________ % to account
for polymorphisms or enhanced sensitivity to new opioids
51. Comprehensive Drug Abuse Prevention and Control Act: establishes
regulations for controlled substances for manufacturers, prescribers,
pharmacists, and distributors
52. naloxone auto-injector pen: Evzio, aka ____________, was fast-tracked
through FDA approval to help prevent OD on rx or illicit opioids
53. avinza: extended release morphine is called
54. 100 times more potent than morphine: Fentanyl
55. direct heat: fentanyl patch use education: warn pts to avoid exposing patch to
_______, because doing so can accelerate drug release
56. ARE NOT: fentanyl products ARE/ARE NOT interchangeable on an mg-by-mg
basis
57. can be used to treat benzo OD: Flumazenil
58. a benzo receptor antagonist: Flumazenil
59. SHORTER: half-life of naloxone is ___________ than half-lives of opioids
60. zohydro: hydrocodone sustained-release formulation that has no abuse-
deterrent properties and therefore its approval is currently being called to be
revoked 61. the emergence of a new pain syndrome refractory to tx & is
atypical or unrelated to original pain: hyperalgesia
62. cognitive behavior therapy (CBT): insomnia first-line treatment (even if
drugs are also employed)
63. code of fed regulations title 21 section 1306 and the United States Code--
controlled substances act title 21 section 829: issuance and filling of
prescriptions is governed by
64. infrequent: Issuance and filling of prescriptions is governed by
