NUR 631 MIDTERM EXAM || LATELY UPDATED
QUESTIONS AND 100% CORRECT ANSWERS WITH A
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The PT time and INR measure what? - ANSWER: extrinsic pathway
The extrinsic pathway is initiated by - ANSWER: tissue factor III
Breast cancer in women who have the breast cancer gene - ANSWER: occurs at
an earlier age
Which leukemia demonstrates the Philedelphia chromosome? - ANSWER: CML
Which leukemia has the best prognosis? - ANSWER: ALL
What causes a hypermetabolic state leading to cachexia? - ANSWER: TNF (tumor
necrosis factor)
What are proto-onocogenes? - ANSWER: Normal cellular genes that promote
growth
What is the major cause of death from leukemic disease? - ANSWER: Infection
The primary source of erythropoietin is... - ANSWER: The kidney
What is the largest cyctoplasmic organelle? - ANSWER: Nucleus
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Which organelle contains the DNA? - ANSWER: Nucelus
Where is the nucleolus?****** - ANSWER: In the nucleus
Where is RNA stored?******* - ANSWER: Nucleolus
What is known as the GI tract of the cell and is coated with ribosomes? -
ANSWER: Rough endoplasmic reticulum
What do the ribosomes do? - ANSWER: Make proteins
Which organlle is responsible for lipid metabolism?******
Abdundant in the muscle for calcium release - ANSWER: Smooth ER
Which organelle stores calcium and detoxes alcohol from the cell? ****** -
ANSWER: Smooth ER
Which organelle is responsible for folding proteins and has cisternae? -
ANSWER: Golgi apparatus
Which organelle is the garbage collector and uses enzymes to digest cellular
waste? - ANSWER: Lysosomes
What organelle is located in the cytoplasm and is responsible for ATP production?
- ANSWER: Mitochondria
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What are the functions of the plasma membrane? - ANSWER: transport nutrients
and waste products, generate membrane potentials, recognition, communication
and growth regulation of cells
What composes the phospholipid bilayer? - ANSWER: Hydrophobic head and
hydrophillic tail
What can pass the bilayer by simple diffusion? - ANSWER: Gases, fat soluable
vitamins and water
what cant pass by simple diffusion? - ANSWER: glucose, sucrose and ions
(hydrogen, sodium, potassium, chloride and calcium)
what must polar charged molecules use to cross the bilayer? - ANSWER: carriers,
proteins or pumps
what is facilitated diffusion? - ANSWER: diffusion (high concentration to low
concentration) but with transmembrane proteins
What is a GLUT protein transporter to transport glucose an example of? -
ANSWER: Facilitated diffusion
Uses combined effects of concentration and electrical gradients - ANSWER:
Electrochemical gradient
What kind of cellular receptor is the sodium potassium pump? - ANSWER: Na K
Pump
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The three types of carrier proteins are - ANSWER: Symporter, antiporter and
uniporter
Moves molecules against concentration gradient using energy - ANSWER:
Primary active transport
Uses primary active transport as a tool - ANSWER: secondary active transport
resting membrane potential - ANSWER: -70mV
Action potential steps: - ANSWER: 1. resting potential
2. sodium rushes into cell (depolarization)
3. absolute refractory point is hit
4. potassium rushes out of cell to lower concentration (repolarization)
5. Na K pump pumps out 3 Na and 2 K to restore RMP
Cell signaling occurs through three methods: - ANSWER: Gap junctions
Cell to cell (antigen presentation)
Ligand (vessicles)
Ligands can be one of three: - ANSWER: Autocrine, paracrine, synaptic
intercellular channels that permit cell to cell transfer of ions and molecules -
ANSWER: gap junctions
Gap junctions found often in which type of cells? - ANSWER: cells where
synchronized functions occur: Cardiac cells, vascular tone and peristalsis