Tietz Fundamentals Of
n n
CLINICAL CHEMISTRY AND
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MOLECULAR DIAGNOSTICS n
7th Edition By Carl A. Burtis
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TEST BANK n
,TietznFundamentalsnofnClinicalnChemistrynandnMolecularnDiagnosticsn7thn EditionnTestnBank
Tablenofncontents:
I.nPrinciplesnOfnLaboratorynMedicine
Chaptern1.nClinicalnChemistry,nMolecularnDiagnostics,nandnLaboratorynMedicine
Chaptern2.nSelectionnandnAnalyticalnEvaluationnofnMethodsn—nWithnStatisticalnTechniques
Chaptern3.nClinicalnEvaluationnofnMethods
Chaptern4.nEvidence-BasednLaboratorynMedicine
Chaptern5.nEstablishmentnandnUsenofnReferencenValues
Chaptern6.nSpecimennCollection,nProcessing,nandnOthernPreanalyticalnVariables
Chaptern7.nQualitynManagement
II.nAnalyticalnTechniquesnAndnInstrumentation
Chaptern8.nPrinciplesnofnBasicnTechniquesnandnLaboratorynSafety
Chaptern9.nOpticalnTechniques
Chaptern10.nElectrochemistrynandnChemicalnSensors
Chaptern11.nElectrophoresis
Chaptern12.nChromatography
Chaptern13.nMassnSpectrometry
Chaptern14.nEnzymenandnRatenAnalyses
Chaptern15.nImmunochemicalnTechniques
Chaptern16nAutomation
Chaptern17.nPoint-of-CarenInstrumentation
III.n Analytes
Chaptern18.nAminonAcids,nPeptides,nandnProteins
Chaptern19.nSerumnEnzymes
Chaptern20.nTumornMarkersnandnCancernGenes
Chaptern21.nKidneynFunctionnTestsn—nCreatinine,nGFR,nUrea,nandnUricnAcid
Chaptern22.nCarbohydrates
Chaptern23.nLipids,nLipoproteins,nApolipoproteins,nandnOthernCardiacnRisknFactors
Chaptern24.nElectrolytesnandnBloodnGases
Chaptern25.nHormones
Chaptern26.n CatecholaminesnandnSerotonin
Chaptern27.n Vitamins,nTracenElements,nNutritionalnAssessment
Chaptern28.nHemoglobin,nIron,nandnBilirubin
Chaptern29.nPorphyrinsnandnPorphyrias
Chaptern30.nTherapeuticnDrugsnandnTheirnManagement
Chaptern31.nClinicalnToxicology
Chaptern32.n ToxicnMetals
IV.n Pathophysiology
Chaptern33.nDiabetes
,Chaptern34.n CardiovascularnDisease
Chaptern35.nKidneynDisease
Chaptern36.n PhysiologynandnDisordersnofnWater,n Electrolyte,nandnAcid-BasenMetabolism
Chaptern37.nnLivernDisease
Chaptern38.n GastrointestinalnandnPancreaticnDiseases
Chaptern39.n DisordersnofnBonenandnMineralnMetabolism
Chaptern40.n DisordersnofnthenPituitarynGland
Chaptern41.n DisordersnofnthenAdrenalnCortex
Chaptern42.n ThyroidnDisorders
Chaptern43.n Reproduction-RelatednDisorders
Chaptern44.nnPregnancynandnPrenatalnTesting
Chaptern45.n NewbornnScreeningnandn InbornnErrorsnofnMetabolism
Chaptern46.nPharmacogenetics
V.n MolecularnDiagnostics
Chaptern47.nPrinciplesnofnMolecularnBiology
Chaptern48.nNucleicnAcidnTechniquesnandnApplications
Chaptern49.nGenomesnandnNucleicnAcidnAlterations
, TietznFundamentalsnofnClinicalnChemistrynandnMolecularDiagnostics,n7enBurtisnTestnBank
Chaptern01:nClinicalnChemistry,nMolecularnDiagnostics,nandnLaboratorynMedicineTestn
Bank
MULTIPLEnCHOICE
1. Annindividualnworkingninnanclinicalnchemistrynlaboratorynisnmarriedntonansalesnrepresentativenw
honworksnfornancompanynthatnsellsnchemistrynlaboratorynsupplies.nWhennthenlaboratorynmanage
rnrequestsnanlistnofnneedednsupplies,ncostnofnsupplies,nandnvendors,nthisnindividualnonlynrecomme
ndsnthenspouse’sncompanynasnthenvendor.nThisnisnconsideredntonbena(n):
a. accountingnissue.
b. possiblenconflictnofninterest.
c. maintenancenofnconfidentialitynissue.
d. problemnwithnresourcenallocation.
ANS:n B
Concernnhasnbeennraisednoverntheninterrelationshipsnbetweennpractitionersninnthenmedicalnfieldna
ndncommercialnsuppliersnofndrugs,ndevices,nequipment,netc.,ntonthenmedicaln profession.
Similarly,nrelationshipsnhavenbeennscrutinizednbetweennclinicalnlaboratoriansnandnmanufacturer
snandnprovidersnofndiagnosticnequipmentnandnsupplies.nThesenconcernsnlednthenNationalnInstitute
snofnHealthn(NIH)ninn1995ntonrequirenofficialninstitutionalnreviewnofnfinancialndisclosurenbynresea
rchersnandnmanagementnofnsituationsninnwhichndisclosurenindicatesnpotentialnconflictsnofninterest.
DIF: 1 REF:nnnPagen4-5 OBJ:n 6n|n7
2. Anpatientnvisitsnhernphysiciannstatingnthatnhernprescribednpainkillernisnnotnworkingntonreducent
henpainnfollowingnhernrecentnsurgery.nAnfriendnofnthenpatientnclaimsnthatnthensamenpainkillern“
workednwonders”ntonreducenhernpainnafternthensamensurgery.nThenphysiciannstatesnthatnthendiff
erenceninntheneffectnofnthendrugnmightnbencausednby
,nwhichnisnstudiedninnpharmacogenetics.
a. epidemiology
b. anninheritedndisease
c. anconflictnofninterest
d. angeneticnvariationninndrug-metabolizingnenzymes
ANS:n D
Pharmacogeneticsnisnthenstudynofnthengeneticnvariationnofndrugnmetabolismnbetweenni
ndividuals.
DIF: 1 REF:nnn Pagen3 OBJ:n 1
3. Johnnworksninnanmolecularndiagnosticsnlaboratorynandnreceivesnanbloodnsamplenthatnhasnthenn
amenofnanclosenfriendnprintednonnthenbar-
codednlabel.nThengeneticntestnthatnisnorderednonnthenfriend’snsamplenwouldnprovidendiagnosticn
informationnaboutnandisordernthatnhasnanpoornprognosis,nandnthentestnisnusuallynperformednbynJ
ohn.nHenasksnanfellownemployeentonanalyzenthensamplenfornhimnandnnotndivulgenthenresults.nTh
isnethicalnissuenconcerns:
a. confidentialitynofnpatientngeneticnandnmedicalninformation.
b. anconflictnofninterest.
c. resourcenallocation.
d. diagnosticnaccuracy.