UNDERSTANDING PATHOPHYSIOLOGY f f
6th EDITION HUETHER
f
f f
CHAPTER 1-42 TEST BANK f f f
Chapterf01:fCellularfBiology
Huetherf&fMcCance:fUnderstandingfPathophysiology,f6thfEdition
MULTIPLEfCHOICE
1. Afstudentfisfobservingfafcellfunderfthefmicroscope.fItfisfobservedftofhavefsupercoile
dfDNAwithfhistones.fWhichfofftheffollowingfwouldfalsofbefobservedfbyfthefstudent?
a. Afsinglefcircularfchromosome
b. Afnucleus
c. Free-floatingfnuclearfmaterial
d. Noforganelles
ANS:f B
Thefcellfdescribedfisfafeukaryoticfcell,fsofitfhasfhistonesfandfafsupercoiledfDNAfwit
hinfitsnucleus;fthus,fthefnucleusfshouldfbefobserved.fAfsinglefcircularfchromosom
efcalledfafprokaryotefcontainsffree-floatingfnuclearfmaterialfbutfhasfnoforganelles.
REF:f p.f2
2. Afnursefisfinstructingfthefstafffaboutfcellularffunctions.fWhichfcellularffunctionfisfthe
nursefdescribingfwhenfanfisolatedfcellfabsorbsfoxygenfandfusesfitftoftransformfnutrie
f
ntsftofenergy?
,a. Metabolicfabsorption
b. Communication
c. Secretion
d. Respiration
ANS:f D
Thefcell’sfabilityftofabsorbfoxygenfisfreferredftofasfrespirationfwhilefitsfcommunicati
onfabilityinvolvesfmaintenancefoffafsteadyfdynamicfstate,fmetabolicfabsorptionfpro
videsfnutrition,fandfsecretionfallowsfforfthefsynthesizingfoffnewfsubstances.
REF:f p.f2
,3. AfeukaryoticfcellfisfundergoingfDNAfreplication.fInfwhichfregionfoffthefcellfwouldfmo
stfofthefgeneticfinformationfbefcontained?
a. Mitochondria
b. Ribosome
c. Nucleolus
d. NucleusfCytoplasm
ANS:f C
Thefregionfoffthefcellfthatfcontainsfgeneticfmaterial,fincludingfaflargefamountfoffribon
ucleicacid,fmostfoffthefDNA,fandfDNA-
bindingfproteins,fisfthefnucleolus,fwhichfisflocatedfwithinthefcell’sfnucleus.fMitochon
driafisfassociatedfwithfcellularfrespiration,fwhilefribosomesfarefinvolvedfwithfproteinf
manufacturing.fCytoplasmfisfaffluidffillingfthatfisfafcomponentfoffthef cell.
REF:f p.f2
, 4. Whichfofftheffollowingfcanfremovefproteinsfattachedftofthefcell’sfbilayerfbyfdis
solvingfthelayerfitself?
a. Peripheralfmembranefproteins
b. Integralfmembranefproteins
c. Glycoproteins
d. Cellfadhesionfmolecules
ANS:f B
Proteinsfdirectlyfattachedftofthefmembranefbilayerfcanfbefremovedfbyfthefactionfoffint
egralmembranefproteinsfthatfdissolvefthefbilayer.fPeripheralfmembranefproteinsfresid
efatfthefsurfacefwhilefcellfadhesionfmoleculesfarefonfthefoutsidefoffthefmembrane.fGlyc
oproteinfmarksfcellsfandfdoesfnotf float.
REF:f p.f7
5. Whichfofftheffollowingfcanfbindftofplasmafmembranefreceptors?
a. Oxygen
b. Ribosomes
c. Amphipathicflipids
d. Ligands
ANS:f D
Ligandsfarefthefonlyfspecificfmoleculesfthatfcanfbindfwithfreceptorsfonfthefcellfmembrane.
REF:f p.f9
6. Afnursefisfreviewingfafreportffromfafpatientfwithfmetastaticfcancer.fWhatfalternati
onfinftheextracellularfmatrixfwouldfsupportfthefdiagnosisfoffmetastaticfcancer?
a. Decreasedffibronectin
b. Increasedfcollagen
c. Decreasedfelastin
d. Increasedfglycoproteins
ANS:f A
Onlyfafreducedfamountfofffibronectinfisffoundfinfsomeftypesfoffcancerousfcells,fallowingthe
mftoftravelforfmetastasize.
6th EDITION HUETHER
f
f f
CHAPTER 1-42 TEST BANK f f f
Chapterf01:fCellularfBiology
Huetherf&fMcCance:fUnderstandingfPathophysiology,f6thfEdition
MULTIPLEfCHOICE
1. Afstudentfisfobservingfafcellfunderfthefmicroscope.fItfisfobservedftofhavefsupercoile
dfDNAwithfhistones.fWhichfofftheffollowingfwouldfalsofbefobservedfbyfthefstudent?
a. Afsinglefcircularfchromosome
b. Afnucleus
c. Free-floatingfnuclearfmaterial
d. Noforganelles
ANS:f B
Thefcellfdescribedfisfafeukaryoticfcell,fsofitfhasfhistonesfandfafsupercoiledfDNAfwit
hinfitsnucleus;fthus,fthefnucleusfshouldfbefobserved.fAfsinglefcircularfchromosom
efcalledfafprokaryotefcontainsffree-floatingfnuclearfmaterialfbutfhasfnoforganelles.
REF:f p.f2
2. Afnursefisfinstructingfthefstafffaboutfcellularffunctions.fWhichfcellularffunctionfisfthe
nursefdescribingfwhenfanfisolatedfcellfabsorbsfoxygenfandfusesfitftoftransformfnutrie
f
ntsftofenergy?
,a. Metabolicfabsorption
b. Communication
c. Secretion
d. Respiration
ANS:f D
Thefcell’sfabilityftofabsorbfoxygenfisfreferredftofasfrespirationfwhilefitsfcommunicati
onfabilityinvolvesfmaintenancefoffafsteadyfdynamicfstate,fmetabolicfabsorptionfpro
videsfnutrition,fandfsecretionfallowsfforfthefsynthesizingfoffnewfsubstances.
REF:f p.f2
,3. AfeukaryoticfcellfisfundergoingfDNAfreplication.fInfwhichfregionfoffthefcellfwouldfmo
stfofthefgeneticfinformationfbefcontained?
a. Mitochondria
b. Ribosome
c. Nucleolus
d. NucleusfCytoplasm
ANS:f C
Thefregionfoffthefcellfthatfcontainsfgeneticfmaterial,fincludingfaflargefamountfoffribon
ucleicacid,fmostfoffthefDNA,fandfDNA-
bindingfproteins,fisfthefnucleolus,fwhichfisflocatedfwithinthefcell’sfnucleus.fMitochon
driafisfassociatedfwithfcellularfrespiration,fwhilefribosomesfarefinvolvedfwithfproteinf
manufacturing.fCytoplasmfisfaffluidffillingfthatfisfafcomponentfoffthef cell.
REF:f p.f2
, 4. Whichfofftheffollowingfcanfremovefproteinsfattachedftofthefcell’sfbilayerfbyfdis
solvingfthelayerfitself?
a. Peripheralfmembranefproteins
b. Integralfmembranefproteins
c. Glycoproteins
d. Cellfadhesionfmolecules
ANS:f B
Proteinsfdirectlyfattachedftofthefmembranefbilayerfcanfbefremovedfbyfthefactionfoffint
egralmembranefproteinsfthatfdissolvefthefbilayer.fPeripheralfmembranefproteinsfresid
efatfthefsurfacefwhilefcellfadhesionfmoleculesfarefonfthefoutsidefoffthefmembrane.fGlyc
oproteinfmarksfcellsfandfdoesfnotf float.
REF:f p.f7
5. Whichfofftheffollowingfcanfbindftofplasmafmembranefreceptors?
a. Oxygen
b. Ribosomes
c. Amphipathicflipids
d. Ligands
ANS:f D
Ligandsfarefthefonlyfspecificfmoleculesfthatfcanfbindfwithfreceptorsfonfthefcellfmembrane.
REF:f p.f9
6. Afnursefisfreviewingfafreportffromfafpatientfwithfmetastaticfcancer.fWhatfalternati
onfinftheextracellularfmatrixfwouldfsupportfthefdiagnosisfoffmetastaticfcancer?
a. Decreasedffibronectin
b. Increasedfcollagen
c. Decreasedfelastin
d. Increasedfglycoproteins
ANS:f A
Onlyfafreducedfamountfofffibronectinfisffoundfinfsomeftypesfoffcancerousfcells,fallowingthe
mftoftravelforfmetastasize.
